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TitleCrystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 A resolution: hydration at the platinated site.
Journal, issue, pagesNucleic Acids Res., Vol. 27, Page 1837-1846, Year 1999
Publish dateJan 5, 1998 (structure data deposition date)
AuthorsCoste, F. / Malinge, J.M. / Serre, L. / Shepard, W. / Roth, M. / Leng, M. / Zelwer, C.
External linksNucleic Acids Res. / PubMed:10101191
MethodsX-ray diffraction
Resolution1.63 Å
Structure data

PDB-1a2e:
CRYSTAL STRUCTURE OF A DOUBLE-STRANDED DNA DECAMER CONTAINING A CISPLATIN INTERSTRAND CROSS-LINK ADDUCT
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

Chemicals

ChemComp-CPT:
Cisplatin / medication, chemotherapy*YM

ChemComp-HOH:
WATER

KeywordsDNA / ANTITUMOR DRUG / CIS-DDP / INTERSTRAND CROSS-LINK

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