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| Title | Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1). |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 42, Page 971-980, Year 1999 |
| Publish date | Jul 27, 1998 (structure data deposition date) |
Authors | Ettmayer, P. / France, D. / Gounarides, J. / Jarosinski, M. / Martin, M.S. / Rondeau, J.M. / Sabio, M. / Topiol, S. / Weidmann, B. / Zurini, M. / Bair, K.W. |
External links | J. Med. Chem. / PubMed:10090780 |
| Methods | X-ray diffraction |
| Resolution | 1.8 - 2.1 Å |
| Structure data | ![]() PDB-1bm2: ![]() PDB-1bmb: |
| Chemicals | ![]() ChemComp-HOH: |
| Source |
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Keywords | HORMONE/GROWTH FACTOR / SH2 DOMAIN / SIGNAL TRANSDUCTION / ADAPTOR PROTEIN / RAS PATHWAY / CYCLIC PEPTIDE / HORMONE-GROWTH FACTOR COMPLEX |
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