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TitleCrystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with (m7GpppA)pUpU (Cap-0) and S-Adenosyl-L-homocysteine (SAH).
Journal, issue, pagesTo Be Published
Publish dateJun 19, 2025 (structure data deposition date)
AuthorsMinasov, G. / Shuvalova, L. / Maltseva, N. / Kim, Y. / Kiryukhina, O. / Joachimiak, A. / Satchell, K.J.F. / Center for Structural Biology of Infectious Diseases (CSBID)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-9p6p:
Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with (m7GpppA)pUpU (Cap-0) and S-Adenosyl-L-homocysteine (SAH).
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-CL:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-ZN:
Unknown entry

ChemComp-MGT:
7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

Source
  • severe acute respiratory syndrome coronavirus 2
KeywordsTRANSFERASE / Viral Protein / Center for Structural Biology of Infectious Diseases (CSBID) / 2'-O-Methyltransferase / Structural Genomics

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