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eF-site ID
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6ugw-A |
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PDB Code
|
6ugw |
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Chain
|
A |
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click to enlarge
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Title
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Crystal structure of the Fc fragment of PF06438179/GP1111 an infliximab biosimilar in a C-centered orthorhombic crystal form, Lot A |
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Classification
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IMMUNE SYSTEM |
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Compound
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PF-06438179/GP1111 Fc |
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Source
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(IGG1_HUMAN) |
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Sequence
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A: |
GPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFN
WYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNG
KEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRD
ELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPP
VLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHY
TQKSLSL
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Description
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Functional site
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1)
|
chain |
A |
| residue |
426-432 |
| type |
prosite |
| sequence |
FSCSVMH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FSCSVMH
|
| source |
prosite : PS00290
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2)
|
chain |
A |
| residue |
300 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:19358553
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| source |
Swiss-Prot : SWS_FT_FI1
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