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6UGW

Crystal structure of the Fc fragment of PF06438179/GP1111 an infliximab biosimilar in a C-centered orthorhombic crystal form, Lot A

Summary for 6UGW
Entry DOI10.2210/pdb6ugw/pdb
DescriptorPF-06438179/GP1111 Fc, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (5 entities in total)
Functional Keywordsantibody, biologic, biosimilar, infliximab, fragment crystallizable, immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains1
Total formula weight30038.82
Authors
Mayclin, S.J.,Edwards, T.E. (deposition date: 2019-09-26, release date: 2019-11-13, Last modification date: 2023-10-11)
Primary citationLerch, T.F.,Sharpe, P.,Mayclin, S.J.,Edwards, T.E.,Polleck, S.,Rouse, J.C.,Zou, Q.,Conlon, H.D.
Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34:77-87, 2020
Cited by
PubMed: 31650490
DOI: 10.1007/s40259-019-00390-1
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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