eF-site ID 6fuj-C PDB Code 6fuj Chain C click to enlarge Title Complement factor D in complex with the inhibitor N-(3'-(aminomethyl)-[1,1'-biphenyl]-3-yl)-3-methylbutanamide Classification HYDROLASE Compound Complement factor D Source (CFAD_HUMAN) Sequence C:  ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAA HCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPD SQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPG TLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHH DGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSG SRVCGNRKKPGIYTRVASYAAWIDSVLA Description (1)  Complement factor D (E.C.3.4.21.46) Functional site 1) chain C residue 61 type sequence D description binding site for residue E8B B 301 source : AC2 2) chain C residue 96 type sequence P description binding site for residue E8B B 301 source : AC2 3) chain C residue 218 type sequence R description binding site for residue E8B B 301 source : AC2 4) chain C residue 57 type sequence H description binding site for residue E8B C 301 source : AC3 5) chain C residue 189 type sequence D description binding site for residue E8B C 301 source : AC3 6) chain C residue 190 type sequence S description binding site for residue E8B C 301 source : AC3 7) chain C residue 191 type sequence C description binding site for residue E8B C 301 source : AC3 8) chain C residue 192 type sequence K description binding site for residue E8B C 301 source : AC3 9) chain C residue 195 type sequence S description binding site for residue E8B C 301 source : AC3 10) chain C residue 215 type sequence S description binding site for residue E8B C 301 source : AC3 11) chain C residue 218 type sequence R description binding site for residue E8B C 301 source : AC3 12) chain C residue 219 type sequence V description binding site for residue E8B C 301 source : AC3 13) chain C residue 57 type ACT_SITE sequence H description Charge relay system source Swiss-Prot : SWS_FT_FI1 14) chain C residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1 15) chain C residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1

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