eF-site ID 6fuj-B PDB Code 6fuj Chain B click to enlarge Title Complement factor D in complex with the inhibitor N-(3'-(aminomethyl)-[1,1'-biphenyl]-3-yl)-3-methylbutanamide Classification HYDROLASE Compound Complement factor D Source (CFAD_HUMAN) Sequence B:  ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAA HCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPD SQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPG TLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHH DGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSG SRVCGNRKKPGIYTRVASYAAWIDSVLA Description (1)  Complement factor D (E.C.3.4.21.46) Functional site 1) chain B residue 41 type sequence L description binding site for residue E8B B 301 source : AC2 2) chain B residue 57 type sequence H description binding site for residue E8B B 301 source : AC2 3) chain B residue 58 type sequence C description binding site for residue E8B B 301 source : AC2 4) chain B residue 189 type sequence D description binding site for residue E8B B 301 source : AC2 5) chain B residue 190 type sequence S description binding site for residue E8B B 301 source : AC2 6) chain B residue 191 type sequence C description binding site for residue E8B B 301 source : AC2 7) chain B residue 192 type sequence K description binding site for residue E8B B 301 source : AC2 8) chain B residue 195 type sequence S description binding site for residue E8B B 301 source : AC2 9) chain B residue 215 type sequence S description binding site for residue E8B B 301 source : AC2 10) chain B residue 218 type sequence R description binding site for residue E8B B 301 source : AC2 11) chain B residue 219 type sequence V description binding site for residue E8B B 301 source : AC2 12) chain B residue 220 type sequence C description binding site for residue E8B B 301 source : AC2 13) chain B residue 61 type sequence D description binding site for residue E8B C 301 source : AC3 14) chain B residue 96 type sequence P description binding site for residue E8B C 301 source : AC3 15) chain B residue 218 type sequence R description binding site for residue E8B C 301 source : AC3 16) chain B residue 57 type ACT_SITE sequence H description Charge relay system source Swiss-Prot : SWS_FT_FI1 17) chain B residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1 18) chain B residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1

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