eF-site ID 5oww-D PDB Code 5oww Chain D click to enlarge Title Crystal structure of human BRD4(1) bromodomain in complex with UT22B Classification DNA BINDING PROTEIN Compound Bromodomain-containing protein 4 Source (BRD4_HUMAN) Sequence D:  SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAW PFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWN AQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI NELPTEE Description Functional site 1) chain D residue 78 type sequence Q description binding site for residue B0Q B 201 source : AC2 2) chain D residue 82 type sequence P description binding site for residue B0Q D 201 source : AC4 3) chain D residue 85 type sequence Q description binding site for residue B0Q D 201 source : AC4 4) chain D residue 87 type sequence V description binding site for residue B0Q D 201 source : AC4 5) chain D residue 92 type sequence L description binding site for residue B0Q D 201 source : AC4 6) chain D residue 140 type sequence N description binding site for residue B0Q D 201 source : AC4 7) chain D residue 140 type SITE sequence N description Acetylated histone binding => ECO:0000269|PubMed:22464331 source Swiss-Prot : SWS_FT_FI1 8) chain D residue 99 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links