eF-site ID 5oww-C PDB Code 5oww Chain C click to enlarge Title Crystal structure of human BRD4(1) bromodomain in complex with UT22B Classification DNA BINDING PROTEIN Compound Bromodomain-containing protein 4 Source (BRD4_HUMAN) Sequence C:  SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAW PFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWN AQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI NELPTEE Description Functional site 1) chain C residue 78 type sequence Q description binding site for residue B0Q A 201 source : AC1 2) chain C residue 81 type sequence W description binding site for residue B0Q C 201 source : AC3 3) chain C residue 82 type sequence P description binding site for residue B0Q C 201 source : AC3 4) chain C residue 85 type sequence Q description binding site for residue B0Q C 201 source : AC3 5) chain C residue 87 type sequence V description binding site for residue B0Q C 201 source : AC3 6) chain C residue 92 type sequence L description binding site for residue B0Q C 201 source : AC3 7) chain C residue 139 type sequence Y description binding site for residue B0Q C 201 source : AC3 8) chain C residue 140 type sequence N description binding site for residue B0Q C 201 source : AC3 9) chain C residue 140 type SITE sequence N description Acetylated histone binding => ECO:0000269|PubMed:22464331 source Swiss-Prot : SWS_FT_FI1 10) chain C residue 99 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI2

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