eF-site ID 5ecg-C PDB Code 5ecg Chain C click to enlarge Title Crystal structure of the BRCT domains of 53BP1 in complex with p53 and H2AX-pSer139 (gammaH2AX) Classification ANTITUMOR PROTEIN Compound Cellular tumor antigen p53 Source Homo sapiens (Human) (5ECG) Sequence C:  ALEEQRGPLPLNKTLFLGYAFLLTMATTIPPFNKQYTESQ LRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCL ASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRI LDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAAS VKQHHSSAIALGVFDVVVTDPSCPASVLKCAEALQLPVVS QEWVIQCLIVGERIGFKQHPKYKHDYV Description Functional site 1) chain C residue 1737 type sequence T description binding site for Di-peptide SEP F 139 and GLN F 140 source : AC4 2) chain C residue 1738 type sequence M description binding site for Di-peptide SEP F 139 and GLN F 140 source : AC4 3) chain C residue 1740 type sequence T description binding site for Di-peptide SEP F 139 and GLN F 140 source : AC4 4) chain C residue 1773 type sequence K description binding site for Di-peptide SEP F 139 and GLN F 140 source : AC4 5) chain C residue 1812 type sequence T description binding site for Di-peptide SEP F 139 and GLN F 140 source : AC4 6) chain C residue 1814 type sequence K description binding site for Di-peptide SEP F 139 and GLN F 140 source : AC4 7) chain C residue 1778 type MOD_RES sequence S description Phosphoserine => ECO:0000269|PubMed:19176521, ECO:0000269|PubMed:21144835 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links