eF-site ID 5cz6-F
PDB Code 5cz6
Chain F

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Title Yeast 20S proteasome beta5-T1A mutant in complex with Syringolin A, propeptide expressed in trans
Classification HYDROLASE/HYDROLASE INHIBITOR
Compound Proteasome subunit alpha type-2
Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c);
Sequence F:  TGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDG
VVFAVEKLITSKLLVPQKNVKIQVVDRHIGCVYSGLIPDG
RHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTL
YNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAAT
GKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE
DNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQK
EIN
Description (1)  PROTEASOME SUBUNIT ALPHA TYPE-2 (E.C.3.4.25.1), PROTEASOME SUBUNIT ALPHA TYPE-3 (E.C.3.4.25.1), PROTEASOME SUBUNIT ALPHA TYPE-4 (E.C.3.4.25.1), PROTEASOME SUBUNIT ALPHA TYPE-5 (E.C.3.4.25.1), PROTEASOME SUBUNIT ALPHA TYPE-6 (E.C.3.4.25.1), PROBABLE PROTEASOME SUBUNIT ALPHA TYPE-7 (E.C.3.4.25.1), PROTEASOME SUBUNIT ALPHA TYPE-1 (E.C.3.4.25.1), PROTEASOME SUBUNIT BETA TYPE-2 (E.C.3.4.25.1), PROTEASOME SUBUNIT BETA TYPE-3 (E.C.3.4.25.1), PROTEASOME SUBUNIT BETA TYPE-4 (E.C.3.4.25.1), PROTEASOME SUBUNIT BETA TYPE-5 (E.C.3.4.25.1), PROTEASOME SUBUNIT BETA TYPE-6 (E.C.3.4.25.1), PROTEASOME SUBUNIT BETA TYPE-7 (E.C.3.4.25.1), PROTEASOME SUBUNIT BETA TYPE-1 (E.C.3.4.25.1), 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE


Functional site

1) chain F
residue 4-26
type prosite
ligand
sequence YDLSNSVFSPDGRNFQVEYAVKA
description Proteasome alpha-type subunits signature.[FYNAGS]-x(4)-[STNLV]-x-[FYW]-S-[PDS]-x(0,1)-G-[RKHDS]-x(2)-Q-[LIVA]-[DENR]-[YH]-[GSAD]-x(2)-[GSAG].
source prosite : PS00388


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