5CZ6

Yeast 20S proteasome beta5-T1A mutant in complex with Syringolin A, propeptide expressed in trans

Summary for 5CZ6

• Entry DOI: 10.2210/pdb5cz6/pdb
• Related: 5CZ4
• Descriptor: Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (18 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, proteasome, mutant, inhibitor, binding analysis, hydrolase/hydrolase inhibitor
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); More
• Total number of polymer chains: 28
• Total formula weight: 732267.56

Authors

Huber, E.M.,Groll, M. (deposition date: 2015-07-31, release date: 2016-03-23, Last modification date: 2024-01-10)

• Primary citation: Huber, E.M.,Heinemeyer, W.,Li, X.,Arendt, C.S.,Hochstrasser, M.,Groll, M.; A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.; Nat Commun, 7:10900-10900, 2016; PubMed: 26964885; DOI: 10.1038/ncomms10900

Experimental method

X-RAY DIFFRACTION (2.7 Å)