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eF-site ID
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4v1m-B |
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PDB Code
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4v1m |
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Chain
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B |
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click to enlarge
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Title
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Architecture of the RNA polymerase II-Mediator core transcription initiation complex |
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Classification
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TRANSCRIPTION |
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Compound
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DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 |
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Source
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ORGANISM_COMMON: BAKER'S YEAST; ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE; |
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Sequence
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B: |
DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTL
QDIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTK
PMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKRTYEA
IDELKYELGKVFIGRLPIMLRSKNCYLSEATESDLYKLKE
CPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPI
SHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLP
YIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEML
KPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKD
ILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKD
QDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQR
TVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMS
SRAGVSQVLNRYTYSSTLSHLRRTNTPIAKPRQLHNTHWG
LVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSE
WGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETL
RTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIV
EDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGL
VEYIDAEEEESILIAMQPEDLEPAEADVDPAKRIRVSHHA
TTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGK
QAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFR
ELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLF
FRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDD
DGLIAPGVRVSGEDVIIGKTTPISSKRDASTPLRSTENGI
VDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKG
TIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIE
CLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRG
FEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARAR
GPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLK
ERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNK
IDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF
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Description
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Functional site
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1)
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chain |
B |
| residue |
1163 |
| type |
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| sequence |
C
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| description |
BINDING SITE FOR RESIDUE ZN B 2225
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| source |
: AC4
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2)
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chain |
B |
| residue |
1166 |
| type |
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| sequence |
C
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| description |
BINDING SITE FOR RESIDUE ZN B 2225
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| source |
: AC4
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3)
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chain |
B |
| residue |
1182 |
| type |
|
| sequence |
C
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| description |
BINDING SITE FOR RESIDUE ZN B 2225
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| source |
: AC4
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4)
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chain |
B |
| residue |
1185 |
| type |
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| sequence |
C
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| description |
BINDING SITE FOR RESIDUE ZN B 2225
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| source |
: AC4
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5)
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chain |
B |
| residue |
837 |
| type |
catalytic |
| sequence |
D
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| description |
788
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| source |
MCSA : MCSA1
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6)
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chain |
B |
| residue |
977-989 |
| type |
prosite |
| sequence |
GDKFASRHGQKGT
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| description |
RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT
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| source |
prosite : PS01166
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7)
|
chain |
B |
| residue |
1185 |
| type |
BINDING |
| sequence |
C
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| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
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