eF-site ID 4bxf-ABCD PDB Code 4bxf Chain A, B, C, D click to enlarge Title 60S ribosomal protein L27A histidine hydroxylase (MINA53 Y209C) in complex with MN(II), 2-oxoglutarate (2OG) and 60S ribosomal protein L27A (RPL27A G37C) peptide fragment Classification OXIDOREDUCTASE/TRANSLATION Compound BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA Source (RL27A_HUMAN) Sequence A:  PSALNFDSPSSLFESLISPIKTETFFKEFWEQKPLLIQRD DPALATYYGSLFKLTDLKSLCSRGMYYGRDVNVCRCVNGK KKVLNKDGKAHFLQLRKDFDQKRATIQFHQPQRFKDELWR IQEKLECYFGSLVGSNVYITPAGSQGLPPHYDDVEVFILQ LEGEKHWRLYHPTVPLARECSVEAEERIGRPVHEFMLKPG DLLYFPRGTIHQADTPAGLAHSTHVTISTYQNNSWGDFLL DTISGLVFDTAKEDVELRTGIPRQLLLQVESTTVATRRLS GFLRTLADRLEGTKELLSSDMKKDFIMHRLPPYSAGDGAE LSTPGGKLPRLDSVVRLQFKDHIVLTVLPAQEKMVYIYHS LKNSRETHMMGNEFHGLRFPLSHLDALKQIWNSPAISVKD LKLTTDEEKESLVLSLWTECLIQVV B:  SALNFDSPSSLFESLISPIKTETFFKEFWEQKPLLIQRDD PALATYYGSLFKLTDLKSLCSRGMYYGRDVNVCRCVNGKK KVLNKDGKAHFLQLRKDFDQKRATIQFHQPQRFKDELWRI QEKLECYFGSLVGSNVYITPAGSQGLPPHYDDVEVFILQL EGEKHWRLYHPTVPLARECSVEAEERIGRPVHEFMLKPGD LLYFPRGTIHQADTPAGLAHSTHVTISTYQNNSWGDFLLD TISGLVFDTAKEDVELRTGIPRQLLLQVESTTVATRRLSG FLRTLADRLEGTKELLSSDMKKDFIMHRLPPYSAGDGAEL STPGGKLPRLDSVVRLQFKDHIVLTVLPQEKMVYIYHSLK NSRETHMMTEFHGLRFPLSHLDALKQIWNSPAISVKDLKL TTDEEKESLVLSLWTECLIQVV C:  GCLHHHRIN D:  GCLHHHRI Description Functional site 1) chain A residue 179 type sequence H description BINDING SITE FOR RESIDUE MN A 601 source : AC1 2) chain A residue 181 type sequence D description BINDING SITE FOR RESIDUE MN A 601 source : AC1 3) chain A residue 240 type sequence H description BINDING SITE FOR RESIDUE MN A 601 source : AC1 4) chain A residue 167 type sequence Y description BINDING SITE FOR RESIDUE AKG A 901 source : AC2 5) chain A residue 179 type sequence H description BINDING SITE FOR RESIDUE AKG A 901 source : AC2 6) chain A residue 181 type sequence D description BINDING SITE FOR RESIDUE AKG A 901 source : AC2 7) chain A residue 194 type sequence K description BINDING SITE FOR RESIDUE AKG A 901 source : AC2 8) chain A residue 240 type sequence H description BINDING SITE FOR RESIDUE AKG A 901 source : AC2 9) chain A residue 253 type sequence H description BINDING SITE FOR RESIDUE AKG A 901 source : AC2 10) chain A residue 255 type sequence T description BINDING SITE FOR RESIDUE AKG A 901 source : AC2 11) chain B residue 179 type sequence H description BINDING SITE FOR RESIDUE MN B 601 source : AC3 12) chain B residue 181 type sequence D description BINDING SITE FOR RESIDUE MN B 601 source : AC3 13) chain B residue 240 type sequence H description BINDING SITE FOR RESIDUE MN B 601 source : AC3 14) chain B residue 179 type sequence H description BINDING SITE FOR RESIDUE AKG B 901 source : AC4 15) chain B residue 181 type sequence D description BINDING SITE FOR RESIDUE AKG B 901 source : AC4 16) chain B residue 194 type sequence K description BINDING SITE FOR RESIDUE AKG B 901 source : AC4 17) chain B residue 240 type sequence H description BINDING SITE FOR RESIDUE AKG B 901 source : AC4 18) chain B residue 253 type sequence H description BINDING SITE FOR RESIDUE AKG B 901 source : AC4 19) chain B residue 255 type sequence T description BINDING SITE FOR RESIDUE AKG B 901 source : AC4 20) chain C residue 39 type MOD_RES sequence H description (3S)-3-hydroxyhistidine => ECO:0000269|PubMed:23103944 source Swiss-Prot : SWS_FT_FI1 21) chain D residue 39 type MOD_RES sequence H description (3S)-3-hydroxyhistidine => ECO:0000269|PubMed:23103944 source Swiss-Prot : SWS_FT_FI1 22) chain B residue 181 type MOD_RES sequence D description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2 23) chain B residue 240 type MOD_RES sequence H description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2 24) chain A residue 309 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:20068231 source Swiss-Prot : SWS_FT_FI3 25) chain B residue 309 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:20068231 source Swiss-Prot : SWS_FT_FI3

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