4BXF

60S ribosomal protein L27A histidine hydroxylase (MINA53 Y209C) in complex with MN(II), 2-oxoglutarate (2OG) and 60S ribosomal protein L27A (RPL27A G37C) peptide fragment

Summary for 4BXF

• Entry DOI: 10.2210/pdb4bxf/pdb
• Related: 2XDV 4BU2 4CCJ 4CCK 4CCM 4CCN 4CCO 4DIQ
• Descriptor: BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA, 60S RIBOSOMAL PROTEIN L27A, MANGANESE (II) ION, ... (5 entities in total)
• Functional Keywords: oxidoreductase-translation complex, oxidoreductase, non-heme, iron-binding, dsbh, dioxygenase, jmjc domain, ribosome biogenesis, nuclear protein, beta-hydroxylation, transcription and epigenetic regulation, signaling, oxidoreductase/translation
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 4
• Total formula weight: 105705.63

Authors

Chowdhury, R.,Schofield, C.J. (deposition date: 2013-07-10, release date: 2014-05-14, Last modification date: 2023-12-20)

• Primary citation: Chowdhury, R.,Sekirnik, R.,Brissett, N.C.,Krojer, T.,Ho, C.H.,Ng, S.S.,Clifton, I.J.,Ge, W.,Kershaw, N.J.,Fox, G.C.,Muniz, J.R.C.,Vollmar, M.,Phillips, C.,Pilka, E.S.,Kavanagh, K.L.,von Delft, F.,Oppermann, U.,McDonough, M.A.,Doherty, A.J.,Schofield, C.J.; Ribosomal oxygenases are structurally conserved from prokaryotes to humans.; Nature, 510:422-426, 2014; PubMed: 24814345; DOI: 10.1038/nature13263

Experimental method

X-RAY DIFFRACTION (2.05 Å)