eF-site ID 4aq3-F PDB Code 4aq3 Chain F click to enlarge Title HUMAN BCL-2 WITH PHENYLACYLSULFONAMIDE INHIBITOR Classification APOPTOSIS Compound APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 1 Source Homo sapiens (Human) (BCLX_HUMAN) Sequence F:  YDNREIVMKYIHYKLSQRGYEWDAEVVHLALRQAGDDFSR RYRGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGR IVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLH TWIQDNGGWDAFVELYG Description (1)  APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 1 Functional site 1) chain F residue 58 type sequence Q description BINDING SITE FOR RESIDUE 398 C 1163 source : AC3 2) chain F residue 161 type sequence Y description BINDING SITE FOR RESIDUE 398 C 1163 source : AC3 3) chain F residue 162 type sequence G description BINDING SITE FOR RESIDUE 398 C 1163 source : AC3 4) chain F residue 63 type sequence F description BINDING SITE FOR RESIDUE 398 F 1163 source : AC6 5) chain F residue 67 type sequence Y description BINDING SITE FOR RESIDUE 398 F 1163 source : AC6 6) chain F residue 70 type sequence D description BINDING SITE FOR RESIDUE 398 F 1163 source : AC6 7) chain F residue 92 type sequence V description BINDING SITE FOR RESIDUE 398 F 1163 source : AC6 8) chain F residue 95 type sequence E description BINDING SITE FOR RESIDUE 398 F 1163 source : AC6 9) chain F residue 108 type sequence A description BINDING SITE FOR RESIDUE 398 F 1163 source : AC6 10) chain F residue 54 type MOD_RES sequence L description Phosphothreonine; by MAPK8 => ECO:0000269|PubMed:18570871 source Swiss-Prot : SWS_FT_FI1 11) chain F residue 55 type MOD_RES sequence A description Phosphoserine; by MAPK8 and PKC => ECO:0000269|PubMed:18570871 source Swiss-Prot : SWS_FT_FI2 12) chain F residue 72 type MOD_RES sequence A description Phosphoserine; by MAPK8 => ECO:0000269|PubMed:18570871 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links