eF-site ID 3s9y-D PDB Code 3s9y Chain D click to enlarge Title Crystal Structure of P. falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP in space group P21, produced from 5-fluoro-6-azido-UMP Classification LYASE Compound Orotidine 5'-phosphate decarboxylase Source Plasmodium falciparum (isolate 3D7) (Q8IJH3_PLAF7) Sequence D:  GFKVKLEKRRNAINTCLCIGLDPDEKDIENFMKNEKENNY NNIKKNLKEKYINNVSIKKDILLKAPDNIIREEKSEEFFY FFNHFCFYIINETNKYALTFKMNFAFYIPYGSVGIDVLKN VFDYLYELNIPTILDMKINDIGNTVKNYRKFIFEYLKSDS CTVNIYMGTNMLKDICYDEEKNKYYSAFVLVKTTNPDSAI FQKNLSLDNKQAYVIMAQEALNMSSYLNLEQNNEFIGFVV GANSYDEMNYIRTYFPNCYILSPGIGAQNGDLHKTLTNGY HKSYEKILINIGRAITKNPYPQKAAQMYYDQINAILKQNM Description Functional site 1) chain D residue 141 type sequence D description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 2) chain D residue 142 type sequence I description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 3) chain D residue 145 type sequence T description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 4) chain D residue 23 type sequence D description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 5) chain D residue 102 type sequence K description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 6) chain D residue 104 type sequence N description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 7) chain D residue 136 type sequence D description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 8) chain D residue 138 type sequence K description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 9) chain D residue 191 type sequence L description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 10) chain D residue 194 type sequence T description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 11) chain D residue 195 type sequence T description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 12) chain D residue 240 type sequence V description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 13) chain D residue 264 type sequence P description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 14) chain D residue 269 type sequence Q description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 15) chain D residue 293 type sequence G description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 16) chain D residue 294 type sequence R description BINDING SITE FOR RESIDUE FNU D 324 source : AC9

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