eF-site ID 3s9y-C PDB Code 3s9y Chain C click to enlarge Title Crystal Structure of P. falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP in space group P21, produced from 5-fluoro-6-azido-UMP Classification LYASE Compound Orotidine 5'-phosphate decarboxylase Source Plasmodium falciparum (isolate 3D7) (Q8IJH3_PLAF7) Sequence C:  MGFKVKLEKRRNAINTCLCIGLDPDEKDIENFMKNEKENN YNNIKKNLKEKYINNVSIKKDILLKAPDNIIREEKSEEFF YFFNHFCFYIINETNKYALTFKMNFAFYIPYGSVGIDVLK NVFDYLYELNIPTILDMKINDIGNTVKNYRKFIFEYLKSD SCTVNIYMGTNMLKDICYDEEKNKYYSAFVLVKTTNPDSA IFQKNLSLDNKQAYVIMAQEALNMSSYLNLEQNNEFIGFV VGANSYDEMNYIRTYFPNCYILSPGIGAQNGDLHKTLTNG YHKSYEKILINIGRAITKNPYPQKAAQMYYDQINAILKQN M Description Functional site 1) chain C residue 299 type sequence N description BINDING SITE FOR RESIDUE PGE B 3000 source : AC4 2) chain C residue 301 type sequence Y description BINDING SITE FOR RESIDUE PGE B 3000 source : AC4 3) chain C residue 305 type sequence A description BINDING SITE FOR RESIDUE PGE B 3000 source : AC4 4) chain C residue 308 type sequence M description BINDING SITE FOR RESIDUE PGE B 3000 source : AC4 5) chain C residue 174 type sequence K description BINDING SITE FOR RESIDUE P6G B 3003 source : AC6 6) chain C residue 224 type sequence M description BINDING SITE FOR RESIDUE P6G B 3003 source : AC6 7) chain C residue 227 type sequence Y description BINDING SITE FOR RESIDUE P6G B 3003 source : AC6 8) chain C residue 23 type sequence D description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 9) chain C residue 102 type sequence K description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 10) chain C residue 104 type sequence N description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 11) chain C residue 136 type sequence D description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 12) chain C residue 138 type sequence K description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 13) chain C residue 191 type sequence L description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 14) chain C residue 194 type sequence T description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 15) chain C residue 195 type sequence T description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 16) chain C residue 240 type sequence V description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 17) chain C residue 264 type sequence P description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 18) chain C residue 269 type sequence Q description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 19) chain C residue 293 type sequence G description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 20) chain C residue 294 type sequence R description BINDING SITE FOR RESIDUE FNU C 324 source : AC7 21) chain C residue 209 type sequence D description BINDING SITE FOR RESIDUE P6G C 3002 source : AC8 22) chain C residue 251 type sequence Y description BINDING SITE FOR RESIDUE P6G C 3002 source : AC8 23) chain C residue 255 type sequence Y description BINDING SITE FOR RESIDUE P6G C 3002 source : AC8 24) chain C residue 141 type sequence D description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 25) chain C residue 142 type sequence I description BINDING SITE FOR RESIDUE FNU D 324 source : AC9 26) chain C residue 145 type sequence T description BINDING SITE FOR RESIDUE FNU D 324 source : AC9

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