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eF-site ID
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3ml4-ACDEFGH |
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PDB Code
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3ml4 |
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Chain
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A, C, D, E, F, G, H |
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click to enlarge
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Title
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Crystal structure of a complex between Dok7 PH-PTB and the MuSK juxtamembrane region |
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Classification
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SIGNALING PROTEIN |
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Compound
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Protein Dok-7 |
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Source
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Mus musculus (Mouse) (MUSK_MOUSE) |
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Sequence
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A: |
EAALVEGQVKLRKWKSRWLVLRKPSPVADCLLXLVYKDKC
ERSKGLRERSSLTLEDICGLEPALPYEGLAHTLAIICLSQ
AVXLGFDSHEAXCAWDTRIRYALGEVHRFHVTVAPGTKLE
SGPATLHLCNDILVLARDIPPTVXGQWKLSDLRRYGAVPN
GFIFEGGTRCGYWAGVFFLSSAEGEQXSFLFDCIVRGISP
TKGPF
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| C: |
EAALVEGQVKLRDGKKWKSRWLVLRKPSPVADCLLXLVYK
DKCERSKGLRERSSLTLEDICGLEPALPYEGLAHTLAIIC
LSQAVXLGFDSHEAXCAWDTRIRYALGEVHRFHVTVAPGT
KLESGPATLHLCNDILVLARDIPPTVXGQWKLSDLRRYGA
VPNGFIFEGGTRCGYWAGVFFLSSAEGEQXSFLFDCIVRG
ISPTKGPF
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| D: |
EAALVEGQVKLRDKWKSRWLVLRKPSPVADCLLXLVYKDK
CERSKGLRERSSLTLEDICGLEPALPYEGLAHTLAIICLS
QAVXLGFDSHEAXCAWDTRIRYALGEVHRFHVTVAPGTKL
ESGPATLHLCNDILVLARDIPPTVXGQWKLSDLRRYGAVP
NGFIFEGGTRCGYWAGVFFLSSAEGEQXSFLFDCIVRGIS
PTKGPF
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| E: |
LHPNPMXQR
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| F: |
LHPNPMXQR
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| G: |
LHPNPMXQR
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| H: |
LHPNPMXQR
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Description
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(1) |
Protein Dok-7, Muscle, skeletal receptor tyrosine-protein kinase
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Functional site
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1)
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chain |
E |
| residue |
553 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:16794080, ECO:0000269|PubMed:20603078
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
F |
| residue |
553 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:16794080, ECO:0000269|PubMed:20603078
|
| source |
Swiss-Prot : SWS_FT_FI1
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3)
|
chain |
G |
| residue |
553 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:16794080, ECO:0000269|PubMed:20603078
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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4)
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chain |
H |
| residue |
553 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:16794080, ECO:0000269|PubMed:20603078
|
| source |
Swiss-Prot : SWS_FT_FI1
|
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