|
|
eF-site ID
|
3jzs-AP |
|
PDB Code
|
3jzs |
|
Chain
|
A, P |
|
click to enlarge
|
|
|
Title
|
Human MDM2 liganded with a 12mer peptide inhibitor (pDIQ) |
|
Classification
|
LIGASE |
|
Compound
|
E3 ubiquitin-protein ligase Mdm2 |
|
Source
|
Homo sapiens (Human) (3JZS) |
|
|
Sequence
|
A: |
TLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKR
LYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYR
NLV
|
| P: |
ETFEHWWSQLLS
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
51 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE EDO P 201
|
| source |
: AC1
|
|
|
2)
|
chain |
P |
| residue |
4 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE EDO P 201
|
| source |
: AC1
|
|
|
3)
|
chain |
P |
| residue |
8 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE EDO P 201
|
| source |
: AC1
|
|
|
4)
|
chain |
P |
| residue |
11 |
| type |
|
| sequence |
L
|
| description |
BINDING SITE FOR RESIDUE EDO P 201
|
| source |
: AC1
|
|
|
5)
|
chain |
P |
| residue |
11 |
| type |
|
| sequence |
L
|
| description |
BINDING SITE FOR RESIDUE EDO P 201
|
| source |
: AC1
|
|
|
|