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eF-site ID
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2zpx-ABC |
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PDB Code
|
2zpx |
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Chain
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A, B, C |
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click to enlarge
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Title
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TNF Receptor Subtype One-selective TNF Mutant with Antagonistic Activity; R1antTNF-T8 |
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Classification
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CYTOKINE |
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Compound
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Tumor necrosis factor |
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Source
|
Homo sapiens (Human) (TNFA_HUMAN) |
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Sequence
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A: |
PSDMPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQ
LVVPSEGLYLIYSQVLFSGQGCPSTHVLLTHTISRITPAI
NRPVNLLSAIRSPCQANPWYEPIYLGGVFQLEPGDRLSAE
INRPDYLDFAESGQVYFGIIAL
|
| B: |
PSDMPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQ
LVVPSEGLYLIYSQVLFSGQGCPSTHVLLTHTISRITPAI
NRPVNLLSAIRSPCQANPWYEPIYLGGVFQLEPGDRLSAE
INRPDYLDFAESGQVYFGIIAL
|
| C: |
PSDMPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQ
LVVPSEGLYLIYSQVLFSGQGCPSTHVLLTHTISRITPAI
NRPVNLLSAIRSPCQANPWYEPIYLGGVFQLEPGDRLSAE
INRPDYLDFAESGQVYFGIIAL
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Description
|
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Functional site
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|
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1)
|
chain |
A |
| residue |
48-64 |
| type |
prosite |
| sequence |
LVVPSEGLYLIYSQVLF
|
| description |
TNF_1 TNF family signature. LvVPsEGLYLIysQVlF
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| source |
prosite : PS00251
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