eF-site ID 2qna-A PDB Code 2qna Chain A click to enlarge Title Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1 (1-65) Classification TRANSPORT PROTEIN Compound Importin subunit beta-1 Source Homo sapiens (Human) (SPN1_HUMAN) Sequence A:  SPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQ LQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFT KANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIM SLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSN VCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPI LTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVP HVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPL VIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAIN DVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAA DVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLR SSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMF NDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQS TAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIG LKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLL ENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLN TLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLK GDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVAC AAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNK AKTLATWATKELRKLKNQGLTRVD Description Functional site 1) chain A residue 830 type sequence G description BINDING SITE FOR RESIDUE SO4 A 1 source : AC1 2) chain A residue 831 type sequence K description BINDING SITE FOR RESIDUE SO4 A 1 source : AC1 3) chain A residue 875 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 1 source : AC1 4) chain A residue 831 type sequence K description BINDING SITE FOR RESIDUE SO4 A 2 source : AC2 5) chain A residue 835 type sequence K description BINDING SITE FOR RESIDUE SO4 A 2 source : AC2 6) chain A residue 835 type MOD_RES sequence K description N-acetylmethionine => ECO:0007744|PubMed:20068231 source Swiss-Prot : SWS_FT_FI1 7) chain A residue 867 type MOD_RES sequence K description N-acetylmethionine => ECO:0007744|PubMed:20068231 source Swiss-Prot : SWS_FT_FI1

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