eF-site ID 1kz7-D
PDB Code 1kz7
Chain D

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Title Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental Isoform of Human Cdc42
Classification SIGNALING PROTEIN
Compound GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS
Source Mus musculus (Mouse) (CDC42_HUMAN)
Sequence D:  MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNY
AVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLV
CFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSAL
TQKGLKNVFDEAILAAL
Description


Functional site

1) chain D
residue 1010
type BINDING
sequence G
description
source Swiss-Prot : SWS_FT_FI1

2) chain D
residue 1115
type BINDING
sequence T
description
source Swiss-Prot : SWS_FT_FI1

3) chain D
residue 1057
type BINDING
sequence D
description BINDING => ECO:0000250
source Swiss-Prot : SWS_FT_FI2

4) chain D
residue 1035
type CARBOHYD
sequence T
description (Microbial infection) O-linked (Glc) threonine; by C.difficile toxins TcdA and TcdB; alternate => ECO:0000269|PubMed:24905543, ECO:0000269|PubMed:7775453, ECO:0000269|PubMed:7777059
source Swiss-Prot : SWS_FT_FI9

5) chain D
residue 1032
type CARBOHYD
sequence Y
description (Microbial infection) O-linked (GlcNAc) tyrosine; by Photorhabdus PAU_02230; alternate => ECO:0000269|PubMed:24141704
source Swiss-Prot : SWS_FT_FI8

6) chain D
residue 1032
type MOD_RES
sequence Y
description (Microbial infection) O-AMP-tyrosine; by Haemophilus IbpA; alternate => ECO:0000269|PubMed:19362538, ECO:0000269|PubMed:20622875
source Swiss-Prot : SWS_FT_FI3

7) chain D
residue 1035
type MOD_RES
sequence T
description (Microbial infection) O-AMP-threonine; by Vibrio VopS => ECO:0000269|PubMed:19039103
source Swiss-Prot : SWS_FT_FI4

8) chain D
residue 1064
type MOD_RES
sequence Y
description Phosphotyrosine; by SRC => ECO:0000269|PubMed:14506284
source Swiss-Prot : SWS_FT_FI5


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