|
|
eF-site ID
|
1gzh-C |
|
PDB Code
|
1gzh |
|
Chain
|
C |
|
click to enlarge
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Title
|
Crystal structure of the BRCT domains of human 53BP1 bound to the p53 tumor supressor |
|
Classification
|
GENE REGULATION |
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Compound
|
CELLULAR TUMOR ANTIGEN P53 |
|
Source
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null (P53_HUMAN) |
|
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Sequence
|
C: |
SSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMF
CQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVR
RCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRH
SVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTI
ITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLR
|
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Description
|
|
Functional site
|
|
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1)
|
chain |
C |
| residue |
183 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE SO4 B 2972
|
| source |
: AC2
|
|
|
2)
|
chain |
C |
| residue |
176 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 1290
|
| source |
: AC3
|
|
|
3)
|
chain |
C |
| residue |
179 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN C 1290
|
| source |
: AC3
|
|
|
4)
|
chain |
C |
| residue |
238 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 1290
|
| source |
: AC3
|
|
|
5)
|
chain |
C |
| residue |
242 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 1290
|
| source |
: AC3
|
|
|
6)
|
chain |
C |
| residue |
237-249 |
| type |
prosite |
| sequence |
MCNSSCMGGMNRR
|
| description |
P53 p53 family signature. MCNSSCMGGMNRR
|
| source |
prosite : PS00348
|
|
|
|