eF-site ID 1gkd-B PDB Code 1gkd Chain B click to enlarge Title MMP9 active site mutant-inhibitor complex Classification HYDROLASE Compound 92 KDA TYPE IV COLLAGENASE Source Homo sapiens (Human) (MM09_HUMAN) Sequence B:  LKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTP LTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFP PGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHQFGHALG LDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY Description Functional site 1) chain B residue 182 type sequence D description BINDING SITE FOR RESIDUE CA B1444 source : AC7 2) chain B residue 183 type sequence G description BINDING SITE FOR RESIDUE CA B1444 source : AC7 3) chain B residue 185 type sequence D description BINDING SITE FOR RESIDUE CA B1444 source : AC7 4) chain B residue 187 type sequence L description BINDING SITE FOR RESIDUE CA B1444 source : AC7 5) chain B residue 205 type sequence D description BINDING SITE FOR RESIDUE CA B1444 source : AC7 6) chain B residue 208 type sequence E description BINDING SITE FOR RESIDUE CA B1444 source : AC7 7) chain B residue 165 type sequence D description BINDING SITE FOR RESIDUE CA B1445 source : AC8 8) chain B residue 197 type sequence G description BINDING SITE FOR RESIDUE CA B1445 source : AC8 9) chain B residue 199 type sequence Q description BINDING SITE FOR RESIDUE CA B1445 source : AC8 10) chain B residue 201 type sequence D description BINDING SITE FOR RESIDUE CA B1445 source : AC8 11) chain B residue 131 type sequence D description BINDING SITE FOR RESIDUE CA B1446 source : AC9 12) chain B residue 206 type sequence D description BINDING SITE FOR RESIDUE CA B1446 source : AC9 13) chain B residue 208 type sequence E description BINDING SITE FOR RESIDUE CA B1446 source : AC9 14) chain B residue 211 type sequence S description BINDING SITE FOR RESIDUE CA B1447 source : BC1 15) chain B residue 212 type sequence L description BINDING SITE FOR RESIDUE CA B1447 source : BC1 16) chain B residue 213 type sequence G description BINDING SITE FOR RESIDUE CA B1447 source : BC1 17) chain B residue 214 type sequence K description BINDING SITE FOR RESIDUE CA B1447 source : BC1 18) chain B residue 215 type sequence G description BINDING SITE FOR RESIDUE CA B1447 source : BC1 19) chain B residue 401 type sequence H description BINDING SITE FOR RESIDUE ZN B1450 source : BC2 20) chain B residue 405 type sequence H description BINDING SITE FOR RESIDUE ZN B1450 source : BC2 21) chain B residue 411 type sequence H description BINDING SITE FOR RESIDUE ZN B1450 source : BC2 22) chain B residue 175 type sequence H description BINDING SITE FOR RESIDUE ZN B1451 source : BC3 23) chain B residue 177 type sequence D description BINDING SITE FOR RESIDUE ZN B1451 source : BC3 24) chain B residue 190 type sequence H description BINDING SITE FOR RESIDUE ZN B1451 source : BC3 25) chain B residue 203 type sequence H description BINDING SITE FOR RESIDUE ZN B1451 source : BC3 26) chain B residue 187 type sequence L description BINDING SITE FOR RESIDUE STN B1448 source : BC6 27) chain B residue 188 type sequence L description BINDING SITE FOR RESIDUE STN B1448 source : BC6 28) chain B residue 189 type sequence A description BINDING SITE FOR RESIDUE STN B1448 source : BC6 29) chain B residue 402 type sequence Q description BINDING SITE FOR RESIDUE STN B1448 source : BC6 30) chain B residue 405 type sequence H description BINDING SITE FOR RESIDUE STN B1448 source : BC6 31) chain B residue 411 type sequence H description BINDING SITE FOR RESIDUE STN B1448 source : BC6 32) chain B residue 422 type sequence M description BINDING SITE FOR RESIDUE STN B1448 source : BC6 33) chain B residue 423 type sequence Y description BINDING SITE FOR RESIDUE STN B1448 source : BC6 34) chain B residue 186 type sequence G description BINDING SITE FOR RESIDUE BUM B1449 source : BC7 35) chain B residue 421 type sequence P description BINDING SITE FOR RESIDUE BUM B1449 source : BC7 36) chain B residue 423 type sequence Y description BINDING SITE FOR RESIDUE BUM B1449 source : BC7 37) chain B residue 131 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 38) chain B residue 165 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 39) chain B residue 182 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 40) chain B residue 183 type BINDING sequence G description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 41) chain B residue 185 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 42) chain B residue 187 type BINDING sequence L description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 43) chain B residue 197 type BINDING sequence G description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 44) chain B residue 199 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 45) chain B residue 201 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 46) chain B residue 205 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 47) chain B residue 206 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 48) chain B residue 208 type BINDING sequence E description BINDING => ECO:0000269|PubMed:12051944 source Swiss-Prot : SWS_FT_FI2 49) chain B residue 190 type BINDING sequence H description BINDING => ECO:0000269|PubMed:12051944, ECO:0000269|PubMed:12077439 source Swiss-Prot : SWS_FT_FI3 50) chain B residue 203 type BINDING sequence H description BINDING => ECO:0000269|PubMed:12051944, ECO:0000269|PubMed:12077439 source Swiss-Prot : SWS_FT_FI3 51) chain B residue 175 type BINDING sequence H description BINDING => ECO:0000269|PubMed:12051944, ECO:0000269|PubMed:12077439 source Swiss-Prot : SWS_FT_FI3 52) chain B residue 177 type BINDING sequence D description BINDING => ECO:0000269|PubMed:12051944, ECO:0000269|PubMed:12077439 source Swiss-Prot : SWS_FT_FI3 53) chain B residue 120 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI4 54) chain B residue 127 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI4

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