1GKD

MMP9 active site mutant-inhibitor complex

Summary for 1GKD

Entry DOI	10.2210/pdb1gkd/pdb
Descriptor	92 KDA TYPE IV COLLAGENASE, CALCIUM ION, 2-{[FORMYL(HYDROXY)AMINO]METHYL}-4-METHYLPENTANOIC ACID, ... (6 entities in total)
Functional Keywords	matrix metalloprotease, hydrolase, glycoprotein
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Secreted, extracellular space, extracellular matrix (Probable): P14780
Total number of polymer chains	2
Total formula weight	38015.96
Authors	Rowsell, S.,Pauptit, R.A. (deposition date: 2001-08-10, release date: 2002-05-16, Last modification date: 2023-12-13)
Primary citation	Rowsell, S.,Hawtin, P.,Minshull, C.A.,Jepson, H.,Brockbank, S.,Barratt, D.,Slater, A.M.,Mcpheat, W.,Waterson, D.,Henney, A.,Pauptit, R.A. Crystal Structure of Mmp9 in Complex with a Reverse Hydroxamate Inhibitor J.Mol.Biol., 319:173-, 2002 Cited by PubMed: 12051944 DOI: 10.1016/S0022-2836(02)00262-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation