eF-site ID 1a94-D PDB Code 1a94 Chain D click to enlarge Title STRUCTURAL BASIS FOR SPECIFICITY OF RETROVIRAL PROTEASES Classification HYDROLASE/HYDROLASE INHIBITOR Compound PROTEASE Source Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) (POL_HV1BR) Sequence D:  PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPG RWEPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPT PVNIIGRNLLTQIGATLNF Description Functional site 1) chain D residue 8 type sequence R description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 2) chain D residue 23 type sequence L description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 3) chain D residue 25 type sequence D description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 4) chain D residue 27 type sequence G description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 5) chain D residue 28 type sequence A description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 6) chain D residue 29 type sequence D description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 7) chain D residue 46 type sequence M description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 8) chain D residue 48 type sequence G description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 9) chain D residue 49 type sequence G description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 10) chain D residue 50 type sequence I description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 11) chain D residue 81 type sequence P description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 12) chain D residue 82 type sequence V description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 13) chain D residue 84 type sequence I description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 14) chain D residue 64 type SITE sequence I description Cleavage; by viral protease => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 15) chain D residue 64 type MOD_RES sequence I description Phosphotyrosine; by host => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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