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- PDB-4dv4: Crystal structure of the Thermus thermophilus 30S ribosomal subun... -

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基本情報

登録情報
データベース: PDB / ID: 4dv4
タイトルCrystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A914G
要素
  • (ribosomal protein ...) x 20
  • 16S rRNA
キーワードRIBOSOME (リボソーム) / decoding / Streptomycin (ストレプトマイシン) / RNA structure (核酸構造) / antibiotic resistance (抗微生物薬耐性)
機能・相同性
機能・相同性情報


small ribosomal subunit / tRNA binding / rRNA binding / リボソーム / structural constituent of ribosome / 翻訳 (生物学) / ribonucleoprotein complex / mRNA binding / zinc ion binding / metal ion binding / 細胞質
類似検索 - 分子機能
Ribosomal protein S4/S9, N-terminal domain / Ribosomal Protein S4 Delta 41; Chain A, domain 1 / S16 Ribosomal Protein; Chain: A; / Ribosomal protein S16 / Ribosomal protein S18 / 30s Ribosomal Protein S18 / 30s ribosomal protein s13; domain 2 / Ribosomal protein S13/S18, C-terminal domain / Ribosomal protein S20 / 30s Ribosomal Protein S19; Chain A ...Ribosomal protein S4/S9, N-terminal domain / Ribosomal Protein S4 Delta 41; Chain A, domain 1 / S16 Ribosomal Protein; Chain: A; / Ribosomal protein S16 / Ribosomal protein S18 / 30s Ribosomal Protein S18 / 30s ribosomal protein s13; domain 2 / Ribosomal protein S13/S18, C-terminal domain / Ribosomal protein S20 / 30s Ribosomal Protein S19; Chain A / Ribosomal protein S19/S15 / Ribosomal protein S3, C-terminal domain / Ribosomal Protein S14/S29 / 30s Ribosomal Protein S14; Chain N / Ribosomal Protein S8; Chain: A, domain 1 - #30 / RNA-binding S4 domain / Ribosomal Protein S7 / Ribosomal protein S7/S5 / Ribosomal protein S6/Translation elongation factor EF1B / Ribosomal protein S3 C-terminal domain / Helix hairpin bin / Dna Ligase; domain 1 - #10 / Ribosomal protein S11/S14 / Ribosomal protein S10 / Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A / S15/NS1, RNA-binding / K homology (KH) domain / Double Stranded RNA Binding Domain - #20 / Helicase, Ruva Protein; domain 3 - #50 / Glucose-6-phosphate isomerase like protein; domain 1 / Ribosomal Protein S8; Chain: A, domain 1 / Ribosomal Protein S5; domain 2 - #10 / 30S ribosomal protein Thx / 30S ribosomal protein Thx / 30S ribosomal protein / GMP Synthetase; Chain A, domain 3 / Ribosomal Protein S5; domain 2 / Double Stranded RNA Binding Domain / Ribosomal protein S14, type Z / Helicase, Ruva Protein; domain 3 / Nucleic acid-binding proteins / Dna Ligase; domain 1 / Methane Monooxygenase Hydroxylase; Chain G, domain 1 / Ribosomal protein S14/S29 / Ribosomal protein S3, bacterial-type / Ribosomal protein S6, conserved site / Ribosomal protein S6 signature. / Ribosomal protein S19, bacterial-type / Ribosomal protein S7, bacterial/organellar-type / Ribosomal protein S11, bacterial-type / Ribosomal protein S13, bacterial-type / Ribosomal protein S20 / Ribosomal protein S20 superfamily / Ribosomal protein S20 / Ribosomal protein S9, bacterial/plastid / Ribosomal protein S4, bacterial-type / 30S ribosomal protein S17 / Ribosomal protein S5, bacterial-type / Ribosomal protein S6, plastid/chloroplast / Ribosomal protein S2, bacteria/mitochondria/plastid / Ribosomal protein S18, conserved site / Ribosomal protein S18 signature. / Ribosomal protein S16 / Ribosomal protein S16 / Ribosomal protein S16 domain superfamily / Ribosomal protein S15, bacterial-type / Ribosomal protein S6 / Ribosomal protein S6 / Ribosomal protein S6 superfamily / Ribosomal protein S12, bacterial-type / Translation elongation factor EF1B/ribosomal protein S6 / Ribosomal protein S18 / Ribosomal protein S18 / Ribosomal protein S18 superfamily / KHドメイン / K homology RNA-binding domain / Ribosomal protein S3, conserved site / Ribosomal protein S14, conserved site / Ribosomal protein S10, conserved site / : / K Homology domain, type 2 / Ribosomal protein S3, C-terminal / Ribosomal protein S3, C-terminal domain superfamily / Ribosomal protein S15/S19, conserved site / KHドメイン / Few Secondary Structures / イレギュラー / Ribosomal protein S19/S15 / Ribosomal protein S19/S15, superfamily / Ribosomal protein S10 / Ribosomal protein S3, C-terminal domain / Ribosomal protein S3 signature. / Ribosomal protein S10 signature. / Ribosomal protein S14 signature. / Ribosomal protein S7, conserved site / Ribosomal protein S17, conserved site / K homology domain superfamily, prokaryotic type / Ribosomal protein S19 / Ribosomal protein S2 signature 1. / Ribosomal protein S13, conserved site
類似検索 - ドメイン・相同性
: / リボ核酸 / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Small ribosomal subunit protein uS12 / Small ribosomal subunit protein uS14 / Small ribosomal subunit protein uS17 / Small ribosomal subunit protein uS8 / Small ribosomal subunit protein uS7 ...: / リボ核酸 / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Small ribosomal subunit protein uS12 / Small ribosomal subunit protein uS14 / Small ribosomal subunit protein uS17 / Small ribosomal subunit protein uS8 / Small ribosomal subunit protein uS7 / Small ribosomal subunit protein uS2 / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS4 / Small ribosomal subunit protein uS9 / Small ribosomal subunit protein uS11 / Small ribosomal subunit protein uS13 / Small ribosomal subunit protein bS20 / Small ribosomal subunit protein uS12 / Small ribosomal subunit protein uS10 / Small ribosomal subunit protein uS19 / 30S ribosomal protein S17 / 30S ribosomal protein S14 type Z / 30S ribosomal protein S8 / Small ribosomal subunit protein uS5 / Small ribosomal subunit protein bTHX / Small ribosomal subunit protein uS15 / Small ribosomal subunit protein bS16 / Small ribosomal subunit protein bS6 / Small ribosomal subunit protein bS18
類似検索 - 構成要素
生物種Thermus thermophilus (サーマス・サーモフィルス)
手法X線回折 / シンクロトロン / フーリエ合成 / 解像度: 3.651 Å
データ登録者Demirci, H. / Murphy IV, F. / Murphy, E. / Gregory, S.T. / Dahlberg, A.E. / Jogl, G.
引用ジャーナル: To be Published
タイトル: A structural basis for streptomycin resistance
著者: Demirci, H. / Murphy IV, F. / Murphy, E. / Gregory, S.T. / Dahlberg, A.E. / Jogl, G.
履歴
登録2012年2月22日登録サイト: RCSB / 処理サイト: RCSB
改定 1.02013年2月27日Provider: repository / タイプ: Initial release

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構造の表示

構造ビューア分子:
MolmilJmol/JSmol

ダウンロードとリンク

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集合体

登録構造単位
A: 16S rRNA
B: ribosomal protein S2
C: ribosomal protein S3
D: ribosomal protein S4
E: ribosomal protein S5
F: ribosomal protein S6
G: ribosomal protein S7
H: ribosomal protein S8
I: ribosomal protein S9
J: ribosomal protein S10
K: ribosomal protein S11
L: ribosomal protein S12
M: ribosomal protein S13
N: ribosomal protein S14
O: ribosomal protein S15
P: ribosomal protein S16
Q: ribosomal protein S17
R: ribosomal protein S18
S: ribosomal protein S19
T: ribosomal protein S20
U: ribosomal protein THX
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)791,058310
ポリマ－783,95221
非ポリマー7,106289
水7,422412
1


  • 登録構造と同一
  • 登録者が定義した集合体
タイプ名称対称操作数
identity operation1_555x,y,z1
単位格子
Length a, b, c (Å)402.638, 402.638, 174.747
Angle α, β, γ (deg.)90.000, 90.000, 90.000
Int Tables number92
Space group name H-MP41212

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要素

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RNA鎖 , 1種, 1分子 A

#1: RNA鎖 16S rRNA /


分子量: 494186.781 Da / 分子数: 1 / 変異: A914G / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: GenBank: M26923.1

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Ribosomal protein ... , 20種, 20分子 BCDEFGHIJKLMNOPQRSTU

#2: タンパク質 ribosomal protein S2 /


分子量: 29317.703 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: P80371
#3: タンパク質 ribosomal protein S3 /


分子量: 26751.076 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: P80372
#4: タンパク質 ribosomal protein S4 /


分子量: 24373.447 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: P80373
#5: タンパク質 ribosomal protein S5 /


分子量: 17583.416 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: Q5SHQ5
#6: タンパク質 ribosomal protein S6 /


分子量: 11988.753 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: Q5SLP8
#7: タンパク質 ribosomal protein S7 /


分子量: 18050.973 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: P17291
#8: タンパク質 ribosomal protein S8 /


分子量: 15868.570 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: Q5SHQ2, UniProt: P0DOY9*PLUS
#9: タンパク質 ribosomal protein S9 /


分子量: 14410.614 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: P80374
#10: タンパク質 ribosomal protein S10 /


分子量: 11954.968 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: Q5SHN7
#11: タンパク質 ribosomal protein S11 /


分子量: 13737.868 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: P80376
#12: タンパク質 ribosomal protein S12 /


分子量: 14966.846 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: F6DEQ7, UniProt: Q5SHN3*PLUS
#13: タンパク質 ribosomal protein S13 /


分子量: 14338.861 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: P80377
#14: タンパク質 ribosomal protein S14 /


分子量: 7158.725 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: Q5SHQ1, UniProt: P0DOY6*PLUS
#15: タンパク質 ribosomal protein S15 /


分子量: 10578.407 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: Q5SJ76
#16: タンパク質 ribosomal protein S16 /


分子量: 10409.983 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: Q5SJH3
#17: タンパク質 ribosomal protein S17 /


分子量: 12324.670 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: Q5SHP7, UniProt: P0DOY7*PLUS
#18: タンパク質 ribosomal protein S18 /


分子量: 10258.299 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: Q5SLQ0
#19: タンパク質 ribosomal protein S19 / 40S ribosomal protein S19


分子量: 10605.464 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: Q5SHP2
#20: タンパク質 ribosomal protein S20 /


分子量: 11736.143 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: P80380
#21: タンパク質・ペプチド ribosomal protein THX / リボソーム


分子量: 3350.030 Da / 分子数: 1 / 由来タイプ: 天然
由来: (天然) Thermus thermophilus (サーマス・サーモフィルス)
株: HB8 / 参照: UniProt: Q5SIH3

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非ポリマー , 3種, 701分子

#22: 化合物...
ChemComp-MG / MAGNESIUM ION / マグネシウムジカチオン


分子量: 24.305 Da / 分子数: 287 / 由来タイプ: 合成 / 式: Mg
#23: 化合物 ChemComp-ZN / ZINC ION


分子量: 65.409 Da / 分子数: 2 / 由来タイプ: 合成 / 式: Zn
#24: 水 ChemComp-HOH / water / 水


分子量: 18.015 Da / 分子数: 412 / 由来タイプ: 天然 / 式: H2O

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実験情報

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実験

実験手法: X線回折 / 使用した結晶の数: 1

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試料調製

結晶マシュー密度: 4.52 Å3/Da / 溶媒含有率: 72.77 %
結晶化温度: 277 K / 手法: ハンギングドロップ法 / pH: 6.5 / 詳細: MPD, pH 6.5, HANGING DROP, temperature 277K

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データ収集

回折平均測定温度: 100 K
放射光源由来: シンクロトロン / サイト: APS / ビームライン: 24-ID-C / 波長: 0.98 Å
検出器タイプ: ADSC QUANTUM 315 / 検出器: CCD / 日付: 2010年11月7日
放射モノクロメーター: Kohzu HLD8-24 / プロトコル: SINGLE WAVELENGTH / 単色(M)・ラウエ(L): M / 散乱光タイプ: x-ray
放射波長波長: 0.98 Å / 相対比: 1
反射解像度: 3.65→35 Å / Num. all: 155290 / Num. obs: 155290 / % possible obs: 98.3 % / Observed criterion σ(F): -3 / Observed criterion σ(I): -3 / 冗長度: 3.2 % / Rmerge(I) obs: 0.08 / Χ2: 1.095 / Net I/σ(I): 13.5
反射 シェル
解像度 (Å)冗長度 (%)Rmerge(I) obsNum. unique allΧ2Diffraction-ID% possible all
3.65-3.783.20.686155211.027199.5
3.78-3.933.20.479155471.056199.5
3.93-4.113.20.345155621.077199.5
4.11-4.333.20.226155361.084199.3
4.33-4.63.20.152156031.128199.2
4.6-4.953.20.109155541.146199.1
4.95-5.453.20.082155961.013198.7
5.45-6.233.20.074155791.112198.4
6.23-7.843.20.065155581.209197.5
7.84-353.10.037152341.103192.7

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解析

ソフトウェア
名称バージョン分類NB
DENZOデータ削減
SCALEPACKデータスケーリング
PHENIXdev_978精密化
PDB_EXTRACT3.1データ抽出
HKL-2000データ収集
PHENIXdev_978位相決定
精密化構造決定の手法: フーリエ合成 / 解像度: 3.651→34.661 Å / Occupancy max: 1 / Occupancy min: 0.18 / FOM work R set: 0.8683 / SU ML: 0.28 / σ(F): 1.33 / 位相誤差: 20.06 / 立体化学のターゲット値: ML
Rfactor反射数%反射Selection details
Rfree0.2083 7744 4.99 %FROM PDB ENTRY 2VQE
Rwork0.1531 ---
obs0.1559 155190 98.2 %-
all-155190 --
溶媒の処理減衰半径: 0.86 Å / VDWプローブ半径: 1.1 Å / 溶媒モデル: FLAT BULK SOLVENT MODEL / Bsol: 108.135 Å2 / ksol: 0.253 e/Å3
原子変位パラメータBiso max: 512.42 Å2 / Biso mean: 168.7769 Å2 / Biso min: 23.96 Å2
Baniso -1Baniso -2Baniso -3
1--6.6447 Å2-0 Å20 Å2
2---6.6447 Å20 Å2
3---6.993 Å2
精密化ステップサイクル: LAST / 解像度: 3.651→34.661 Å
タンパク質核酸リガンド溶媒全体
原子数19088 32508 289 412 52297
拘束条件
Refine-IDタイプDev ideal数
X-RAY DIFFRACTIONf_bond_d0.01356351
X-RAY DIFFRACTIONf_angle_d1.6283602
X-RAY DIFFRACTIONf_chiral_restr0.09110413
X-RAY DIFFRACTIONf_plane_restr0.0094888
X-RAY DIFFRACTIONf_dihedral_angle_d19.90826123
LS精密化 シェル

Refine-ID: X-RAY DIFFRACTION / Total num. of bins used: 30

解像度 (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkNum. reflection all% reflection obs (%)
3.651-3.69250.34832770.29064708498596
3.6925-3.73580.32312560.273449305186100
3.7358-3.78130.30552920.260248905182100
3.7813-3.82920.31782100.24234940515099
3.8292-3.87950.26232640.229749645228100
3.8795-3.93250.29622680.231449145182100
3.9325-3.98870.27362470.209249655212100
3.9887-4.04810.25322800.20194874515499
4.0481-4.11130.25212850.19694916520199
4.1113-4.17850.23012410.17744966520799
4.1785-4.25050.25792530.17284932518599
4.2505-4.32760.23072600.16264896515699
4.3276-4.41070.20662750.15754934520999
4.4107-4.50050.20682920.14884906519899
4.5005-4.59820.20552550.14484946520199
4.5982-4.70490.20432380.14164938517699
4.7049-4.82230.19592270.12884992521999
4.8223-4.95230.19142800.12064912519299
4.9523-5.09760.17362560.1174945520199
5.0976-5.26160.16432380.10894933517199
5.2616-5.44890.17032530.11124958521199
5.4489-5.66620.18052650.1134931519699
5.6662-5.92290.16562540.10994949520398
5.9229-6.23340.17652460.11464941518798
6.2334-6.62150.18832540.12884926518098
6.6215-7.12860.18722540.12934937519198
7.1286-7.83850.18772520.124952520497
7.8385-8.95560.16032590.1224900515996
8.9556-11.21920.16862580.13374914517295
11.2192-34.66240.24922550.20874637489287
精密化 TLS

手法: refined / Refine-ID: X-RAY DIFFRACTION

IDL11 (°2)L12 (°2)L13 (°2)L22 (°2)L23 (°2)L33 (°2)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T11 (Å2)T12 (Å2)T13 (Å2)T22 (Å2)T23 (Å2)T33 (Å2)Origin x (Å)Origin y (Å)Origin z (Å)
10.46790.0607-0.17990.7321-0.04330.7272-0.0422-0.067-0.16040.23510.14470.15530.30320.1095-0.09410.94440.22360.14180.86230.00851.2228143.796783.4974-12.4037
23.2738-0.74520.56620.7278-0.03170.4253-0.1659-1.69220.54660.51810.2798-0.3263-0.1840.0154-0.1321.3611-0.17020.08362.6209-0.79021.7503223.1421129.26499.7966
34.57942.7112-0.94621.9399-0.65150.54140.0232-0.4971-1.07040.1344-0.0346-0.8330.26240.24830.02121.23960.19560.06321.2996-0.15581.5783167.142271.6603-25.8784
42.8592.23530.47115.8695-3.23073.2159-0.83390.43050.1598-1.04830.8783-1.0575-0.95090.72740.01541.9701-0.35550.6080.9360.1161.9136156.5959158.2079-34.432
56.03854.3746-4.02534.833-4.66294.5463-0.55950.33310.3309-1.9044-1.2453-1.44090.66670.50091.72592.12850.0120.59371.12470.20891.771153.0961150.8058-37.0977
66.43381.86012.97326.02133.68069.36250.4349-1.6531.2239-0.0286-0.24882.1538-0.2274-1.2061-0.14161.3478-0.57140.56071.105-0.15152.3589148.5263160.3437-19.9234
75.5644-1.93453.9173.11942.34868.63310.9505-0.04951.3052-0.7795-0.8409-0.6786-1.37251.6126-0.1191.4637-0.07550.77651.18390.14921.7489166.1889163.0068-17.7609
83.72742.072.34443.376-1.15874.24450.2426-0.66281.2170.34111.3079-0.7658-1.46521.135-1.4031.1922-0.07460.52381.3744-0.55941.7375174.5652156.3996-6.5609
90.1880.07380.2140.9003-0.28640.39920.0909-0.04890.90340.80660.5351-1.0666-0.72520.7713-0.55212.965-1.03930.72092.3574-1.01543.2481193.1362167.0842.3093
109.89645.51753.37383.75871.21893.2644-0.05190.10030.36520.33540.5354-0.5533-0.30020.8876-0.4231.2929-0.05460.50351.0147-0.57272.1997174.3299155.5796-10.7106
112.7815-2.17721.15442.81770.36912.83810.34790.1905-0.5512-1.49310.4885-0.9065-0.17110.766-0.65161.7394-0.18610.73260.7261-0.36622.0983157.4436151.8662-23.0595
127.1949-1.7602-2.52832.0824.46559.8582-0.25540.39120.8573-0.29620.0414-1.3981-1.23640.47650.05622.0632-0.13750.78120.78740.04632.2033158.1361167.9716-20.9763
130.0041-0.0104-0.04380.16860.51861.5879-0.5013-0.0259-0.16550.41830.7404-0.10150.70170.3444-0.14594.9441-0.36750.42171.4026-0.37363.558163.79174.6313-22.5827
14-0.00550.00320.00460.04570.25941.6761-0.16240.46730.0513-0.1873-0.05640.4158-0.72840.2207-0.11731.91640.2060.35773.218-1.54131.6458210.0473139.347527.5733
158.6827-2.93183.07895.8807-2.05957.5552-0.8845-0.82532.0287-0.1529-0.6924-0.29520.3727-1.92891.51981.69230.3606-0.06953.5427-0.30161.5227206.6954145.033135.2056
164.60480.18381.79292.52730.29310.8448-0.2265-0.48590.2580.59480.5359-0.2678-0.0952-0.1602-0.25932.3789-0.23110.40624.7311-0.9832.8754192.5431142.082144.8238
170.05360.0879-0.00310.2514-0.08010.05050.0861-0.29040.11040.54090.1164-0.1627-0.29370.2207-0.05122.4375-0.0063-0.08632.8183-1.22020.7737207.1543140.018746.6629
185.2775-0.34854.50630.0709-0.2983.8444-1.2-1.26991.21010.7681-0.67550.1401-0.5645-1.89091.64782.5110.513-0.33763.6553-1.05652.0141192.5449146.599630.7334
191.3986-1.7880.40816.71760.02691.30150.0814-0.3099-0.12780.55340.36331.11450.2377-0.2273-0.32951.1389-0.02640.33123.6196-0.52011.6184187.085130.380619.2082
208.16097.5946-3.84578.2505-5.06753.68630.2278-0.77831.87911.0974-0.2972-0.4944-0.80870.57280.14591.2583-0.3174-0.32482.7217-0.82142.4849196.4708144.773810.0069
215.09724.4259-4.32725.9458-5.16374.6052-0.735-1.9897-0.03170.53810.09560.49430.5164-0.62380.54811.54180.25170.06153.8832-0.26541.3396195.2807126.614123.8892
224.9920.2698-2.14640.18190.4993.21120.92030.4855-0.0157-0.5798-0.0589-0.4526-0.45980.0907-0.50140.73860.0780.27933.1975-0.90441.8842194.6684138.119516.8234
235.8039-5.7583-1.95625.86152.82446.4520.1268-0.5174-0.3110.47241.05620.62750.269-0.0869-1.122.33290.0935-0.2971.29260.02751.5977153.6308111.347737.7086
244.81590.58520.01354.5625-1.89760.80160.5063-2.06941.45540.1714-0.5073-0.4383-0.33590.92910.07431.69140.09740.0321.6489-0.45360.9631159.6377112.855725.8186
257.7359-1.33072.54891.9756-0.53932.0168-0.12660.8899-0.4156-0.615-0.5174-0.62711.24430.11830.53891.27340.37740.28561.2337-0.39571.378138.9533105.724520.0003
266.4373-0.31223.31826.4345-1.11066.0475-0.0067-0.74970.41260.6787-0.30670.26630.005-0.91470.33761.62470.16090.58351.1055-0.00550.8819132.4034107.258439.6899
272.1921-1.388-2.1022.58732.5392.86510.23721.0150.65570.3962-0.77960.2789-1.08480.43620.44571.33160.10020.51111.09880.22951.3556147.3457112.985617.468
284.5188-2.348-2.95637.57532.89278.21980.0087-1.36951.41290.85860.3569-0.60660.52460.8193-0.45090.9276-0.0122-0.17051.8453-0.52311.3221165.13125.42497.2555
295.93583.1497-4.56673.7523-0.80634.79730.2044-0.476-0.39420.4715-0.5042-0.7485-0.66440.71810.26791.02680.0310.02262.2349-0.65481.5826185.8258122.5471-2.9561
304.2316-4.6002-4.47997.20172.73416.8974-0.2152-0.71571.10420.74780.1137-0.13070.2576-0.31680.08071.1488-0.35830.31321.2991-0.69331.3446162.5949129.18764.9831
315.095-5.62146.28856.2094-6.94347.7714-0.8452-1.24741.35711.18620.7302-0.595-1.55760.10820.0951.3127-0.12970.19471.3789-0.47421.3708168.3974133.04725.8064
324.18466.17381.06219.14541.31872.0980.7797-0.13731.41750.46-0.63651.4448-0.9188-0.2876-0.09920.93940.16040.35561.4833-0.03251.4889145.7663129.00870.8195
334.59391.0872-6.39954.4926-1.5659.0165-0.88840.2561-0.8579-0.51370.0052-0.32870.1013-0.72540.74791.10550.37080.02150.9719-0.41611.394148.4369117.5721-2.5257
349.19273.57925.5799.57232.03915.9228-0.3957-1.5759-0.4331.25390.31330.52221.38560.53920.0260.7349-0.03770.20970.80.04580.6971152.3544118.19322.3793
353.8928-5.826-2.0779.13254.06673.35110.73961.45130.7061-0.346-0.7212-0.4558-0.53621.003-0.01111.13160.01060.17321.3094-0.16590.6378155.7671124.677-4.5756
364.7966-3.50584.97543.4167-3.76615.1771-0.2635-1.45010.5941.3514-0.47131.5287-1.4494-2.01360.49491.0280.30410.37071.2771-0.01751.1912136.0148134.2321-8.7958
378.4635-1.229-5.77453.74011.39396.4189-0.1363-0.16530.29390.6692-0.21710.6492-0.71070.74340.28891.91-0.0126-0.04711.5709-0.1040.674168.1191117.0808-84.7339
381.63451.97792.55172.83634.64589.45580.4551.93160.8632-1.54660.222-0.8562-1.59831.7617-0.65962.250.51061.0642.59220.23721.9125187.2982116.8494-96.4528
395.52021.1627-6.76310.8537-1.55248.3006-0.93381.0669-0.2322-1.2710.4902-0.06640.26560.26340.29232.21030.2387-0.26212.0707-0.51010.5428174.336112.5356-98.4609
404.4821-0.6068-1.78097.9789-2.28153.46290.23890.14560.1748-0.27120.13160.1384-1.3344-0.2799-0.30762.4664-0.2285-0.06052.4120.34591.2365166.0317118.9797-91.4573
419.0688-4.14937.3763.7093-2.16758.61940.03060.84060.323-0.722-0.2926-0.1612-1.5661-0.18210.21662.5128-0.12750.80982.58350.0931.0112184.5456126.5323-88.8698
425.4029-4.85692.98164.7779-0.97119.0555-0.3851.3441-0.3804-1.10580.1935-2.32730.18421.92170.18961.1014-0.13410.09841.9475-0.07221.5156190.4506117.9308-83.1256
430.4658-0.7081.25382.6452-1.54733.7628-0.36830.2590.111-0.51140.66910.7894-0.6264-0.8666-0.30391.66620.3840.24521.58230.33380.9785172.1474119.3507-88.5309
443.1636-2.0303-0.74782.8199-2.86138.57320.309-0.1283-1.94820.74950.04590.59681.1011-0.1845-0.31492.21310.21240.52360.52960.02151.9269169.0448106.3997-85.3032
452.98393.4186-0.54515.3777-3.66136.40290.69380.8539-1.0515-0.623-0.7682-0.61420.54030.9064-0.02341.4483-0.05880.30092.2349-0.48291.0172177.8431112.7123-85.8996
464.55515.09114.72876.1425.92645.8058-0.88210.20011.5671-0.6749-0.0291.1168-0.3101-0.20110.9021.4024-0.0365-0.21451.70021.20372.2643165.8753131.478-73.491
474.05385.70541.42398.03821.96780.6611-0.68953.01833.68590.0583-0.19332.0486-0.52330.43190.74331.2606-0.3130.20812.0525-0.00883.4101217.949143.3084-22.5168
488.02432.197-0.01122.0265-1.75266.7517-0.2544-0.26431.32770.41780.15810.0526-0.2555-0.6561-0.01410.9813-0.08050.65151.7114-0.29822.4514239.842146.0514-22.1063
495.13912.6526.58577.18342.14719.5748-1.74873.08350.65270.31730.6902-0.6346-0.74121.67430.99321.6198-0.12790.33991.92840.18922.2883248.3481145.5091-29.834
502.74323.21051.46786.05641.49322.06630.3601-0.67980.52860.373-0.39010.67480.9032-1.12190.10081.5826-0.4322-0.20353.9503-0.16491.0856226.2467131.3325-38.3479
519.84168.1780.84098.39761.43864.6418-0.07880.42020.12650.05140.98390.86252.15950.1297-0.78592.27290.329-0.05992.78720.26691.4312219.868124.4762-38.0245
523.12292.2463.60921.81022.11835.5664-0.05140.52070.78680.4139-0.2438-0.05090.2708-0.59770.30281.1089-0.43390.31151.5927-0.27632.9441236.2705135.9484-30.2632
534.8049-2.2279-0.22262.153-0.71796.2255-0.19890.4474-0.8396-0.3930.2295-0.48340.31441.73760.17320.7947-0.18540.7431.7937-0.21822.1866251.5171135.7008-30.3005
544.99094.36611.44324.5209-0.98547.994-0.66881.8735-2.2799-0.8209-0.296-2.35691.09011.34990.89461.37780.14630.30841.83530.07482.0469238.5117129.4711-40.1487
559.58671.9899.6018.33241.0039.73720.6937-0.55151.7915-0.55830.6889-0.7536-0.71660.1878-1.21992.37890.01821.50352.161-0.3012.7386220.1606126.0246-44.4671
567.86062.2054-0.43055.7971-0.67182.3004-0.19010.0991-0.2886-0.40160.02660.04610.83130.53890.25251.30150.16571.04191.0408-0.32251.1203140.7536123.2702-30.3246
575.17043.97553.48864.63385.3639.51060.2378-0.31090.5446-0.27990.04211.4021-0.9124-1.3121-0.22370.88580.43310.31660.85220.37241.2904131.6766128.6396-28.5683
587.87310.6374.89549.19853.84184.623-0.69630.51331.4711-0.04160.31430.683-1.9462-0.7920.38161.0160.22760.22520.70060.17911.4196132.3355132.9524-34.4452
594.8482.98210.64593.3850.56131.7570.435-0.44110.68481.21150.1010.06630.09750.0652-0.47750.92720.32480.11450.87710.04980.8614141.5499126.4837-19.5875
605.16043.32550.98325.05680.64394.76530.0885-1.3089-0.40441.3894-0.08710.45540.12360.0544-0.0451.26570.27990.55811.00320.16120.9012129116.8117-13.8231
615.89134.92351.23944.17371.73917.2490.2726-1.03340.28170.6796-0.9610.09920.7191-0.00670.69741.01010.24770.17130.81150.13740.6875126.9765118.5558-17.0748
621.1956-1.01680.06515.31471.60321.94070.349-0.36420.9896-0.22960.2016-0.2693-0.53370.5361-0.4621.6118-0.5667-0.23591.8473-1.0243.4536241.8092166.284-3.5712
637.66223.7199-6.27392.2338-3.16385.16810.77140.34182.69430.0755-0.079-0.085-1.10670.2646-0.69151.4669-0.31070.93612.8705-0.95063.6084250.4003155.8662-7.8058
641.8442-0.32111.75760.21470.33414.7778-0.5940.20240.9548-0.1298-0.25190.0385-1.01670.14610.74011.9379-0.319-0.61251.7192-0.59973.8551242.6606164.5265-11.1249
656.92322.2661.22681.6519-0.35052.77010.42150.23710.1059-0.12090.57060.498-0.09930.5274-0.66630.9373-0.28060.23051.4786-0.93273.5898236.7428163.9201-7.8485
662.76211.0834-1.69260.4886-0.84193.55-0.63170.42360.4075-0.94650.1868-0.36880.4642-0.42150.39251.9021-0.47540.70992.0905-0.81154.434229.6272166.9468-14.5935
673.1627-3.73620.07067.1748-2.86913.90310.4539-0.192-0.1106-0.1432-0.4361.16750.0664-0.3038-0.02741.1362-0.48440.19612.5708-1.1651.9526223.8193131.8713-3.6778
680.197-0.01940.24460.1861-0.10780.34131.05450.4419-0.24910.0001-0.70470.67690.3202-0.2151-0.1072.66220.45680.16622.7651-1.70532.9843227.4607157.380328.8221
699.3124-2.2614-3.18066.7753-5.03376.7169-0.015-0.01380.85091.8420.5563-0.07-1.4739-0.8208-0.38561.82970.4535-0.26973.5928-1.61122.7791218.3103165.218227.4131
703.68790.9981-1.75053.0394-3.21733.54750.1603-0.45591.19441.38170.4296-1.4604-2.95290.8419-0.54212.6762-0.3548-0.21892.7208-1.72743.5305228.5488166.356523.6398
712.058-2.0118-0.9373.49572.76246.28840.1937-0.34590.72870.57210.07990.0603-0.07781.5977-0.46841.9272-0.34941.00663.5152-0.94762.1708224.4398139.992116.8071
721.1516-0.03660.07931.4066-1.65852.1858-0.75890.0629-0.098-0.88870.5012-0.7126-0.6738-0.52160.282.1963-0.32710.19443.2716-1.00271.9193219.0537136.530614.1054
730.2595-0.1404-0.00210.3014-0.07240.0249-0.2732-0.07030.0791.18450.34490.2036-0.9332-0.0482-0.01372.94460.1970.25872.7063-1.78193.0077227.2707171.080436.5778
740.01010.1-0.09770.9152-0.9010.88630.6558-2.30161.66751.2018-0.07940.4258-0.58910.4145-0.46561.5491-0.25630.09714.3964-1.81773.563217.0381159.985535.5205
750.09580.0647-0.08040.0554-0.09490.1872-0.74520.3013-0.3628-0.3281-0.19360.91040.1783-0.60430.78932.70890.3931-0.08183.584-1.84532.5589229.2788156.30733.9229
766.9752-1.50065.98616.6708-3.11365.9267-0.61240.64410.0785-0.22580.0269-0.3901-0.0763-0.71280.5361.1720.0460.40830.912-0.10281.7804213.3262118.7404-69.6454
778.47621.6358-3.11737.0762.09932.42240.06730.4590.4456-1.00820.625-1.8506-0.60062.0882-0.66450.9797-0.06450.50441.4088-0.04871.7137217.7317114.8645-66.4202
786.67081.12113.30399.3313-1.94218.92950.4780.38650.62161.1031-0.7471-1.32330.70940.62950.32380.8691-0.15880.21841.5509-0.39651.4217220.4299120.6477-61.799
795.6091-5.889-3.42518.96446.45025.0172-1.45291.3888-0.9351-2.3601-0.7175-0.76010.4452-0.4571.88461.0784-0.4170.21941.97540.23821.3512211.589124.9827-71.6836
804.70086.0221-3.89119.5811-4.34513.44120.7918-2.31040.69391.99260.1115-0.5876-1.79460.6794-0.79891.29290.2215-0.31821.9449-0.4211.0979211.4358126.4922-59.3473
816.15853.10415.13651.94763.09224.9423-0.1407-0.4691.38470.4549-1.712-1.3763-1.77941.87981.73391.3259-0.52190.04591.37570.52932.3119211.8708130.3499-69.5682
822.02711.15330.53125.1721-4.38646.02780.9310.6930.2085-0.3566-0.4329-0.7312-0.49140.8007-0.43771.5876-0.32290.74991.9083-0.54831.6583193.9026110.5739-57.909
835.16862.59523.73153.7344-0.24734.5492-0.02221.0343-0.2688-0.3078-0.0153-0.71480.18690.7290.05010.60520.19140.08521.1581-0.26621.6665145.038899.3176-27.5011
843.9648-6.1544.03379.7407-6.46194.38740.67661.2809-1.0784-0.9366-1.1101-0.62491.40961.84960.47041.05040.00910.08751.41430.09761.0567153.785290.0644-15.4226
857.5224-0.8136-3.27894.6592-4.11376.29610.3770.7489-0.2512-0.80220.66280.72371.1948-0.8185-1.01211.61810.5699-0.61021.56950.31971.6605161.164577.7041.3697
866.47676.28651.83489.26351.40666.3979-0.50561.39-0.76540.36470.8305-0.93351.3851.4789-0.30491.31150.38560.10961.40090.00861.4406176.454576.73344.1593
873.80085.2662-1.9677.9706-0.38289.68830.1379-0.1360.617-0.0044-1.0811-0.99380.2381.030.87471.3620.2617-0.191.33080.23451.3776173.828278.42028.3815
886.2902-1.3197-1.51657.0393-1.76232.31580.1743-1.48760.53910.1713-0.318-1.11930.82650.74130.06581.47560.4684-0.30021.97920.01961.382170.486181.250624.2805
898.5049-4.78594.02085.4665-4.53283.7584-0.7149-0.7558-0.0971-0.58930.11560.40781.3672-0.66610.44561.4963-0.1010.21991.9895-0.52652.3706274.5324116.2178-8.0306
903.34382.2838-0.41095.8585-1.94655.97410.4246-0.6771.7690.6903-0.92490.0527-0.47460.69790.47550.86610.1222-0.30272.3583-0.57032.1613275.3163120.86-0.1664
917.33940.9357-6.59155.4501-3.72287.5095-0.0441-0.9615-0.18090.1532-0.48760.3650.3541-0.27550.53351.5035-0.0087-0.38782.216-0.3351.4141257.444699.981310.9996
929.3161.1325-2.15526.471-0.54955.1484-0.835-0.4797-0.4229-0.0248-0.33090.8194-0.1144-0.16821.09020.9939-0.2706-0.15142.5382-0.03732.3619240.9939103.87592.0401
937.2466-1.5844-5.56787.1191-2.37016.17660.091-1.87790.63671.5207-0.21510.25530.28770.170.16862.26210.50580.30333.8276-1.08721.7129220.4743117.235334.0953
940.8481-1.24370.81152.8863-2.66812.8713-0.269-1.06110.44230.92170.27250.6544-0.3539-0.225-0.04771.49780.2272-0.08774.0972-0.50242.1733232.6846119.071235.3911
951.32192.07862.47144.25015.41967.018-0.03411.6429-0.5004-1.8658-1.4768-0.00650.6946-0.21811.41042.28080.36490.41332.4764-0.56011.8025219.1121123.4226.2808
961.1836-1.6989-2.02242.61142.534.7529-0.50410.56120.0137-0.2885-0.1813-1.0140.24870.83110.62821.5858-0.26170.16853.4452-0.41332.1063222.4618131.383524.1193
974.42453.7194-0.02945.6184-2.74646.2665-0.7169-0.24271.2932-0.0985-0.25470.9819-0.5734-0.79390.87691.12240.1205-0.4222.6296-0.85971.8233214.0273137.297518.5691
988.6055-4.18223.41516.3483-0.04314.50041.09061.67890.7366-2.03030.08210.0872-0.5479-0.3505-1.10221.3933-0.0290.11681.51870.44320.9466144.1669106.5699-68.8252
991.9471-3.35491.25516.8417-0.09214.85890.3736-2.7138-0.65610.5150.85450.07880.35741.022-1.1040.97870.1282-0.09671.6321-0.00650.7499143.9823101.9679-56.3298
1003.5067-0.9705-3.2873.08222.80964.363-0.37451.156-1.6082-0.00070.27512.10291.8774-1.83630.10271.5144-0.1613-0.26921.58060.02122.1962131.149598.2865-63.5793
1015.76850.71814.92475.89522.60937.4894-0.19260.1021-0.1692-0.18420.199-0.24750.25450.8244-0.06251.49350.35760.8150.96960.3611.4797112.441972.66639.9573
1027.41341.88615.84181.00320.87667.15440.14330.4053-0.17060.73160.2835-0.19660.26961.0822-0.49511.1740.20880.64121.2347-0.31211.5429118.706278.769815.2999
1035.1134-3.0089-2.51489.4401-2.96113.8291-0.28260.4-0.24260.49250.029-0.44930.7312-0.18670.23871.9953-0.01770.38221.1537-0.02531.3165117.919773.46024.7239
1044.65951.8892.51584.79674.36114.33390.7195-0.24772.13380.1890.99470.3176-1.95280.3422-1.45791.4693-0.39160.56771.17-0.06672.2889111.133284.60418.722
1052.45212.9371-1.97858.52853.11367.5999-0.54350.33930.901-0.6922-0.30810.7186-1.2215-0.25620.73681.42740.38960.40611.47960.96863.0398100.836779.95745.1457
1065.4438-3.88836.78918.0929-2.76851.99970.6844-0.1358-0.693-0.58420.3881.12231.3767-0.0934-1.09511.90550.32540.59950.58840.39561.9106104.160270.84147.6096
1078.15753.6589-0.96875.0974-3.87553.5420.8588-0.9986-0.60641.2819-0.524-0.02250.4694-0.5161-0.36812.3988-0.34150.70631.15140.51312.2014104.369974.632418.4544
1084.91225.79871.36499.478-0.68873.044-0.6066-0.5433-0.51950.7116-1.25242.13680.9855-2.56691.68811.7112-0.15930.97931.522-0.28652.452893.785579.611215.7879
1098.36960.3138-5.33919.82541.0113.5543-0.676-0.23240.46390.20320.71360.18010.2821-0.3718-0.0480.5860.11340.11040.97840.47171.6455119.569685.183-34.4009
1102.94431.84931.04636.4284-3.40143.50020.1331.7238-0.1325-0.64930.3717-0.4846-0.1945-0.5758-0.49591.42250.37480.24992.0367-0.55711.6255122.653672.8298-45.7443
1115.13092.32285.77532.53012.73226.5066-0.13420.2047-0.0523-0.09860.2840.2798-0.68160.6184-0.17990.7214-0.20650.19270.90530.26241.6725126.795588.1514-33.6153
1128.2912-0.48095.13232.0177-0.13633.2124-0.2472-0.8912-0.92260.7421-1.149-0.60750.64580.44671.20270.94470.01010.37081.14940.26130.8729137.932798.5233-21.4787
1130.04550.42970.46075.20275.30865.4232-1.0476-1.1170.475-0.23510.9340.94210.51580.5120.13560.82190.1034-0.02831.1050.18731.7595127.910985.8375-33.2223
1144.27384.2667-5.10958.8286-4.60616.1632-0.12182.42580.6009-1.83070.80332.6490.721-2.0985-0.60261.4495-0.2265-0.33481.69860.45561.8235116.237280.0956-46.1787
1155.19395.05942.02614.93572.06882.1832-0.0515-0.61230.66380.35-0.18350.3505-2.4727-0.86810.23710.76550.0097-0.04610.72130.21171.6368116.473884.8178-34.7735
1165.87-2.76171.92676.68322.82593.21270.0596-0.60740.38790.7084-0.9192-0.1172-0.29980.63860.82350.8923-0.35630.09381.37750.44191.1828117.946280.0702-36.389
1172.1108-3.90510.78167.86-3.45799.39790.45350.0340.6701-0.008-0.0382-0.067-0.13980.489-0.37721.4251-0.1380.29981.37040.03991.0227137.949585.8008-44.7991
1181.4919-2.926-0.98247.16710.77051.5818-0.2848-0.17841.5708-0.00620.0366-0.0422-0.96480.28920.2762.172-0.47460.63190.8144-0.18772.7776180.3871140.5082-64.3524
1197.20316.2623.91138.94085.31163.16390.05050.31720.7266-0.4966-0.90450.6963-1.1747-0.62660.80131.27840.063-0.07712.1640.62811.7032173.1217132.3238-75.65
1204.17384.61011.11586.09031.19567.22680.87621.17041.6432-0.92670.4458-0.5137-2.14160.6164-1.3371.41740.47040.8871.29510.65921.8909181.4794132.9864-74.7031
1216.7625-5.2199-0.95094.32131.69433.29510.5499-0.1241.2809-0.21470.4284-3.9955-0.45373.0207-0.92050.75330.07850.05752.1057-0.59091.8084186.6763128.4432-66.1456
1228.78421.9373-0.87332.60080.53537.07410.4652-0.19281.1702-0.4030.1031-0.5065-0.20641.1762-0.4941.61960.12650.71781.80620.12380.9544178.2956133.9744-60.9068
1232.9302-2.6978-4.79027.33152.16159.35021.4161-0.50250.39330.083-0.09880.8497-0.0669-0.9837-1.21861.3016-0.09920.2071.10550.26421.0479174.9408124.4369-69.0533
1247.1332.03174.71784.74242.9247.58290.45140.1256-0.0222-0.47240.0083-1.46350.59450.5869-0.45091.65140.21790.30571.23830.24921.5879192.3047125.5005-71.7756
1255.71511.5846-4.31447.1274-6.40747.6218-0.61861.8794-0.6177-1.45740.15471.34371.6539-1.38840.42922.23610.805-0.86673.2243-1.17172.3056252.8242112.889428.2785
1261.42571.7826-1.45793.24170.04196.5251-1.021-1.84540.89541.8308-0.6882-0.5171-0.8757-0.41651.482.57170.7484-0.75563.7556-0.63811.6589252.1958100.144342.5608
1273.078-2.4878-3.04413.78533.7894.0057-0.1090.13060.52740.15990.7495-0.7461-0.65231.4971-0.5972.14980.46370.04013.79150.05192.3711252.92488.853539.4864
1281.56282.4955-2.39645.0309-3.38973.8463-0.9196-0.563-0.16850.4684-0.27112.1151-1.0413-1.13461.02911.08370.4135-0.28873.76570.22562.3424245.0707101.275232.0973
1299.37723.86770.54471.83740.31010.0630.2157-0.45580.85870.0641-0.07260.7369-0.2046-0.6733-0.06491.68820.1571-0.11993.75870.13373.0074252.058396.529332.8935
1300.04480.5309-0.10296.4131-2.12573.3065-0.1559-0.7466-1.35710.86230.2262-0.2571-0.11590.4344-0.04561.72960.3931-0.22342.84910.20232.2712248.776893.548426.9649
1310.0920.0772-0.08910.0644-0.07540.08620.53331.25930.7567-1.5255-0.21740.4188-0.5396-0.0835-0.22522.6577-0.4211-0.5663.50771.44261.993253.5796103.136625.8899
1328.4899-6.71765.71516.0539-4.94744.0918-0.9482-0.4691-0.00771.5414-0.0958-1.6017-0.78491.35080.93382.18180.0173-0.18632.72220.52682.206241.920496.25817.1828
1333.26050.14223.14950.69510.83383.9488-0.3753-0.476-0.0960.20660.3960.37120.4673-0.0234-0.10321.4539-0.25750.29260.51660.1361.6141113.556441.5216-14.7732
1347.32952.4288-0.16533.10172.99974.08820.3602-1.21290.0281-0.4069-0.4460.89111.0727-0.29820.2941.8095-0.13170.01660.57330.64791.9254100.623345.0232-25.9153
1355.40640.38483.38676.17813.98794.4038-0.3290.69190.3379-0.0223-0.53950.7630.4411-0.31470.58891.5994-0.52640.31781.31660.53491.836199.600550.3784-35.1173
1369.4715-0.56858.14950.1171-0.37067.17890.40951.1774-0.7598-0.3021-0.39390.31490.40331.00930.0210.9561-0.11460.15482.602-0.25892.4845251.8433124.64192.7463
1377.54282.19312.79313.88911.30965.6840.3025-0.3919-0.00710.157-0.0586-0.3657-1.1240.932-0.1562.0515-0.1943-0.68232.2083-1.17521.9012252.0274131.42068.1749
精密化 TLSグループ
IDRefine-IDRefine TLS-IDSelection detailsAuth asym-IDAuth seq-ID
1X-RAY DIFFRACTION1chain 'A' and (resseq 5:920)A5 - 920
2X-RAY DIFFRACTION2chain 'A' and (resseq 921:1400)A921 - 1400
3X-RAY DIFFRACTION3chain 'A' and (resseq 1401:1544)A0
4X-RAY DIFFRACTION4chain 'B' and (resseq 7:25)B7 - 25
5X-RAY DIFFRACTION5chain 'B' and (resseq 26:43)B26 - 43
6X-RAY DIFFRACTION6chain 'B' and (resseq 44:63)B44 - 63
7X-RAY DIFFRACTION7chain 'B' and (resseq 64:87)B64 - 87
8X-RAY DIFFRACTION8chain 'B' and (resseq 88:121)B88 - 121
9X-RAY DIFFRACTION9chain 'B' and (resseq 122:131)B122 - 131
10X-RAY DIFFRACTION10chain 'B' and (resseq 132:180)B132 - 180
11X-RAY DIFFRACTION11chain 'B' and (resseq 181:207)B181 - 207
12X-RAY DIFFRACTION12chain 'B' and (resseq 208:226)B208 - 226
13X-RAY DIFFRACTION13chain 'B' and (resseq 227:240)B227 - 240
14X-RAY DIFFRACTION14chain 'C' and (resseq 2:50)C2 - 50
15X-RAY DIFFRACTION15chain 'C' and (resseq 51:70)C51 - 70
16X-RAY DIFFRACTION16chain 'C' and (resseq 71:82)C71 - 82
17X-RAY DIFFRACTION17chain 'C' and (resseq 83:101)C83 - 101
18X-RAY DIFFRACTION18chain 'C' and (resseq 102:112)C102 - 112
19X-RAY DIFFRACTION19chain 'C' and (resseq 113:169)C113 - 169
20X-RAY DIFFRACTION20chain 'C' and (resseq 170:182)C170 - 182
21X-RAY DIFFRACTION21chain 'C' and (resseq 183:193)C183 - 193
22X-RAY DIFFRACTION22chain 'C' and (resseq 194:207)C194 - 207
23X-RAY DIFFRACTION23chain 'D' and (resseq 2:34)D2 - 34
24X-RAY DIFFRACTION24chain 'D' and (resseq 35:68)D35 - 68
25X-RAY DIFFRACTION25chain 'D' and (resseq 69:99)D69 - 99
26X-RAY DIFFRACTION26chain 'D' and (resseq 100:194)D100 - 194
27X-RAY DIFFRACTION27chain 'D' and (resseq 195:209)D195 - 209
28X-RAY DIFFRACTION28chain 'E' and (resseq 5:16)E5 - 16
29X-RAY DIFFRACTION29chain 'E' and (resseq 17:27)E17 - 27
30X-RAY DIFFRACTION30chain 'E' and (resseq 28:50)E28 - 50
31X-RAY DIFFRACTION31chain 'E' and (resseq 51:63)E51 - 63
32X-RAY DIFFRACTION32chain 'E' and (resseq 64:79)E64 - 79
33X-RAY DIFFRACTION33chain 'E' and (resseq 80:103)E80 - 103
34X-RAY DIFFRACTION34chain 'E' and (resseq 104:127)E104 - 127
35X-RAY DIFFRACTION35chain 'E' and (resseq 128:141)E128 - 141
36X-RAY DIFFRACTION36chain 'E' and (resseq 142:154)E142 - 154
37X-RAY DIFFRACTION37chain 'F' and (resseq 1:10)F1 - 10
38X-RAY DIFFRACTION38chain 'F' and (resseq 11:15)F11 - 15
39X-RAY DIFFRACTION39chain 'F' and (resseq 16:32)F16 - 32
40X-RAY DIFFRACTION40chain 'F' and (resseq 33:42)F33 - 42
41X-RAY DIFFRACTION41chain 'F' and (resseq 43:47)F43 - 47
42X-RAY DIFFRACTION42chain 'F' and (resseq 48:56)F48 - 56
43X-RAY DIFFRACTION43chain 'F' and (resseq 57:68)F57 - 68
44X-RAY DIFFRACTION44chain 'F' and (resseq 69:81)F69 - 81
45X-RAY DIFFRACTION45chain 'F' and (resseq 82:92)F82 - 92
46X-RAY DIFFRACTION46chain 'F' and (resseq 93:101)F93 - 101
47X-RAY DIFFRACTION47chain 'G' and (resseq 2:11)G2 - 11
48X-RAY DIFFRACTION48chain 'G' and (resseq 12:35)G12 - 35
49X-RAY DIFFRACTION49chain 'G' and (resseq 36:69)G36 - 69
50X-RAY DIFFRACTION50chain 'G' and (resseq 70:78)G70 - 78
51X-RAY DIFFRACTION51chain 'G' and (resseq 79:92)G79 - 92
52X-RAY DIFFRACTION52chain 'G' and (resseq 93:110)G93 - 110
53X-RAY DIFFRACTION53chain 'G' and (resseq 111:129)G111 - 129
54X-RAY DIFFRACTION54chain 'G' and (resseq 130:144)G130 - 144
55X-RAY DIFFRACTION55chain 'G' and (resseq 145:156)G145 - 156
56X-RAY DIFFRACTION56chain 'H' and (resseq 1:19)H1 - 19
57X-RAY DIFFRACTION57chain 'H' and (resseq 20:42)H20 - 42
58X-RAY DIFFRACTION58chain 'H' and (resseq 43:62)H43 - 62
59X-RAY DIFFRACTION59chain 'H' and (resseq 63:95)H63 - 95
60X-RAY DIFFRACTION60chain 'H' and (resseq 96:116)H96 - 116
61X-RAY DIFFRACTION61chain 'H' and (resseq 117:138)H117 - 138
62X-RAY DIFFRACTION62chain 'I' and (resseq 2:32)I2 - 32
63X-RAY DIFFRACTION63chain 'I' and (resseq 33:40)I33 - 40
64X-RAY DIFFRACTION64chain 'I' and (resseq 41:69)I41 - 69
65X-RAY DIFFRACTION65chain 'I' and (resseq 70:88)I70 - 88
66X-RAY DIFFRACTION66chain 'I' and (resseq 89:106)I89 - 106
67X-RAY DIFFRACTION67chain 'I' and (resseq 107:128)I107 - 128
68X-RAY DIFFRACTION68chain 'J' and (resseq 3:12)J3 - 12
69X-RAY DIFFRACTION69chain 'J' and (resseq 13:29)J13 - 29
70X-RAY DIFFRACTION70chain 'J' and (resseq 30:42)J30 - 42
71X-RAY DIFFRACTION71chain 'J' and (resseq 43:49)J43 - 49
72X-RAY DIFFRACTION72chain 'J' and (resseq 50:71)J50 - 71
73X-RAY DIFFRACTION73chain 'J' and (resseq 72:84)J72 - 84
74X-RAY DIFFRACTION74chain 'J' and (resseq 85:94)J85 - 94
75X-RAY DIFFRACTION75chain 'J' and (resseq 95:100)J95 - 100
76X-RAY DIFFRACTION76chain 'K' and (resseq 11:34)K11 - 34
77X-RAY DIFFRACTION77chain 'K' and (resseq 35:52)K35 - 52
78X-RAY DIFFRACTION78chain 'K' and (resseq 53:75)K53 - 75
79X-RAY DIFFRACTION79chain 'K' and (resseq 76:86)K76 - 86
80X-RAY DIFFRACTION80chain 'K' and (resseq 87:99)K87 - 99
81X-RAY DIFFRACTION81chain 'K' and (resseq 100:110)K100 - 110
82X-RAY DIFFRACTION82chain 'K' and (resseq 111:126)K111 - 126
83X-RAY DIFFRACTION83chain 'L' and (resseq 5:12)L5 - 12
84X-RAY DIFFRACTION84chain 'L' and (resseq 13:22)L13 - 22
85X-RAY DIFFRACTION85chain 'L' and (resseq 23:32)L23 - 32
86X-RAY DIFFRACTION86chain 'L' and (resseq 33:69)L33 - 69
87X-RAY DIFFRACTION87chain 'L' and (resseq 70:101)L70 - 101
88X-RAY DIFFRACTION88chain 'L' and (resseq 102:128)L102 - 128
89X-RAY DIFFRACTION89chain 'M' and (resseq 2:14)M2 - 14
90X-RAY DIFFRACTION90chain 'M' and (resseq 15:66)M15 - 66
91X-RAY DIFFRACTION91chain 'M' and (resseq 67:94)M67 - 94
92X-RAY DIFFRACTION92chain 'M' and (resseq 95:119)M95 - 119
93X-RAY DIFFRACTION93chain 'N' and (resseq 2:11)N2 - 11
94X-RAY DIFFRACTION94chain 'N' and (resseq 12:21)N12 - 21
95X-RAY DIFFRACTION95chain 'N' and (resseq 22:31)N22 - 31
96X-RAY DIFFRACTION96chain 'N' and (resseq 32:40)N32 - 40
97X-RAY DIFFRACTION97chain 'N' and (resseq 41:61)N41 - 61
98X-RAY DIFFRACTION98chain 'O' and (resseq 2:49)O2 - 49
99X-RAY DIFFRACTION99chain 'O' and (resseq 50:73)O50 - 73
100X-RAY DIFFRACTION100chain 'O' and (resseq 74:88)O74 - 88
101X-RAY DIFFRACTION101chain 'P' and (resseq 1:8)P1 - 8
102X-RAY DIFFRACTION102chain 'P' and (resseq 9:23)P9 - 23
103X-RAY DIFFRACTION103chain 'P' and (resseq 24:33)P24 - 33
104X-RAY DIFFRACTION104chain 'P' and (resseq 34:52)P34 - 52
105X-RAY DIFFRACTION105chain 'P' and (resseq 53:61)P53 - 61
106X-RAY DIFFRACTION106chain 'P' and (resseq 62:67)P62 - 67
107X-RAY DIFFRACTION107chain 'P' and (resseq 68:76)P68 - 76
108X-RAY DIFFRACTION108chain 'P' and (resseq 77:83)P77 - 83
109X-RAY DIFFRACTION109chain 'Q' and (resseq 2:12)Q2 - 12
110X-RAY DIFFRACTION110chain 'Q' and (resseq 13:17)Q13 - 17
111X-RAY DIFFRACTION111chain 'Q' and (resseq 18:28)Q18 - 28
112X-RAY DIFFRACTION112chain 'Q' and (resseq 29:34)Q29 - 34
113X-RAY DIFFRACTION113chain 'Q' and (resseq 35:45)Q35 - 45
114X-RAY DIFFRACTION114chain 'Q' and (resseq 46:55)Q46 - 55
115X-RAY DIFFRACTION115chain 'Q' and (resseq 56:61)Q56 - 61
116X-RAY DIFFRACTION116chain 'Q' and (resseq 62:81)Q62 - 81
117X-RAY DIFFRACTION117chain 'Q' and (resseq 82:100)Q82 - 100
118X-RAY DIFFRACTION118chain 'R' and (resseq 19:24)R19 - 24
119X-RAY DIFFRACTION119chain 'R' and (resseq 25:36)R25 - 36
120X-RAY DIFFRACTION120chain 'R' and (resseq 37:43)R37 - 43
121X-RAY DIFFRACTION121chain 'R' and (resseq 44:52)R44 - 52
122X-RAY DIFFRACTION122chain 'R' and (resseq 53:59)R53 - 59
123X-RAY DIFFRACTION123chain 'R' and (resseq 60:75)R60 - 75
124X-RAY DIFFRACTION124chain 'R' and (resseq 76:88)R76 - 88
125X-RAY DIFFRACTION125chain 'S' and (resseq 2:12)S2 - 12
126X-RAY DIFFRACTION126chain 'S' and (resseq 13:25)S13 - 25
127X-RAY DIFFRACTION127chain 'S' and (resseq 26:30)S26 - 30
128X-RAY DIFFRACTION128chain 'S' and (resseq 31:40)S31 - 40
129X-RAY DIFFRACTION129chain 'S' and (resseq 41:52)S41 - 52
130X-RAY DIFFRACTION130chain 'S' and (resseq 53:66)S53 - 66
131X-RAY DIFFRACTION131chain 'S' and (resseq 67:71)S67 - 71
132X-RAY DIFFRACTION132chain 'S' and (resseq 72:81)S72 - 81
133X-RAY DIFFRACTION133chain 'T' and (resseq 8:45)T8 - 45
134X-RAY DIFFRACTION134chain 'T' and (resseq 46:75)T46 - 75
135X-RAY DIFFRACTION135chain 'T' and (resseq 76:106)T76 - 106
136X-RAY DIFFRACTION136chain 'U' and (resseq 2:8)U2 - 8
137X-RAY DIFFRACTION137chain 'U' and (resseq 9:25)U9 - 25

+
万見について

-
お知らせ

-
2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

-
2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

+
2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

+
2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

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