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- PDB-4dv6: Crystal structure of the Thermus thermophilus 30S ribosomal subun... -

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Basic information

Entry
Database: PDB / ID: 4dv6
TitleCrystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A915G
Components
  • (ribosomal protein ...) x 20
  • 16S rRNA
KeywordsRIBOSOME / decoding / Streptomycin / RNA structure / antibiotic resistance
Function / homology
Function and homology information


small ribosomal subunit / tRNA binding / rRNA binding / ribosome / structural constituent of ribosome / ribonucleoprotein complex / translation / mRNA binding / zinc ion binding / metal ion binding / cytoplasm
Similarity search - Function
Ribosomal protein S4/S9, N-terminal domain / Ribosomal Protein S4 Delta 41; Chain A, domain 1 / S16 Ribosomal Protein; Chain: A; / Ribosomal protein S16 / Ribosomal protein S18 / 30s Ribosomal Protein S18 / 30s ribosomal protein s13; domain 2 / Ribosomal protein S13/S18, C-terminal domain / Ribosomal protein S20 / 30s Ribosomal Protein S19; Chain A ...Ribosomal protein S4/S9, N-terminal domain / Ribosomal Protein S4 Delta 41; Chain A, domain 1 / S16 Ribosomal Protein; Chain: A; / Ribosomal protein S16 / Ribosomal protein S18 / 30s Ribosomal Protein S18 / 30s ribosomal protein s13; domain 2 / Ribosomal protein S13/S18, C-terminal domain / Ribosomal protein S20 / 30s Ribosomal Protein S19; Chain A / Ribosomal protein S19/S15 / Ribosomal protein S3, C-terminal domain / Ribosomal Protein S14/S29 / 30s Ribosomal Protein S14; Chain N / Ribosomal Protein S8; Chain: A, domain 1 - #30 / RNA-binding S4 domain / Ribosomal Protein S7 / Ribosomal protein S7/S5 / Ribosomal protein S6/Translation elongation factor EF1B / Ribosomal protein S3 C-terminal domain / Helix hairpin bin / Dna Ligase; domain 1 - #10 / Ribosomal protein S11/S14 / Ribosomal protein S10 / Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A / S15/NS1, RNA-binding / K homology (KH) domain / Double Stranded RNA Binding Domain - #20 / Helicase, Ruva Protein; domain 3 - #50 / Glucose-6-phosphate isomerase like protein; domain 1 / Ribosomal Protein S8; Chain: A, domain 1 / Ribosomal Protein S5; domain 2 - #10 / 30S ribosomal protein Thx / 30S ribosomal protein Thx / 30S ribosomal protein / GMP Synthetase; Chain A, domain 3 / Ribosomal Protein S5; domain 2 / Double Stranded RNA Binding Domain / Ribosomal protein S14, type Z / Helicase, Ruva Protein; domain 3 / Nucleic acid-binding proteins / Dna Ligase; domain 1 / Methane Monooxygenase Hydroxylase; Chain G, domain 1 / Ribosomal protein S14/S29 / Ribosomal protein S3, bacterial-type / Ribosomal protein S6, conserved site / Ribosomal protein S6 signature. / Ribosomal protein S19, bacterial-type / Ribosomal protein S7, bacterial/organellar-type / Ribosomal protein S11, bacterial-type / Ribosomal protein S13, bacterial-type / Ribosomal protein S20 / Ribosomal protein S20 superfamily / Ribosomal protein S20 / Ribosomal protein S9, bacterial/plastid / Ribosomal protein S4, bacterial-type / 30S ribosomal protein S17 / Ribosomal protein S5, bacterial-type / Ribosomal protein S6, plastid/chloroplast / Ribosomal protein S2, bacteria/mitochondria/plastid / Ribosomal protein S18, conserved site / Ribosomal protein S18 signature. / Ribosomal protein S16 / Ribosomal protein S16 / Ribosomal protein S16 domain superfamily / Ribosomal protein S15, bacterial-type / Ribosomal protein S6 / Ribosomal protein S6 / Ribosomal protein S6 superfamily / Ribosomal protein S12, bacterial-type / Translation elongation factor EF1B/ribosomal protein S6 / Ribosomal protein S18 / Ribosomal protein S18 / Ribosomal protein S18 superfamily / K Homology domain / K homology RNA-binding domain / Ribosomal protein S3, conserved site / Ribosomal protein S14, conserved site / Ribosomal protein S10, conserved site / : / K Homology domain, type 2 / Ribosomal protein S3, C-terminal / Ribosomal protein S3, C-terminal domain superfamily / Ribosomal protein S15/S19, conserved site / KH domain / Ribosomal protein S19/S15 / Ribosomal protein S19/S15, superfamily / Ribosomal protein S10 / Ribosomal protein S3, C-terminal domain / Few Secondary Structures / Irregular / Ribosomal protein S3 signature. / Ribosomal protein S10 signature. / Ribosomal protein S14 signature. / Ribosomal protein S7, conserved site / Ribosomal protein S17, conserved site / K homology domain superfamily, prokaryotic type / Ribosomal protein S19 / Ribosomal protein S2 signature 1. / Ribosomal protein S13, conserved site
Similarity search - Domain/homology
: / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Small ribosomal subunit protein uS12 / Small ribosomal subunit protein uS14 / Small ribosomal subunit protein uS17 / Small ribosomal subunit protein uS8 / Small ribosomal subunit protein uS7 ...: / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Small ribosomal subunit protein uS12 / Small ribosomal subunit protein uS14 / Small ribosomal subunit protein uS17 / Small ribosomal subunit protein uS8 / Small ribosomal subunit protein uS7 / Small ribosomal subunit protein uS2 / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS4 / Small ribosomal subunit protein uS9 / Small ribosomal subunit protein uS11 / Small ribosomal subunit protein uS13 / Small ribosomal subunit protein bS20 / Small ribosomal subunit protein uS12 / Small ribosomal subunit protein uS10 / Small ribosomal subunit protein uS19 / 30S ribosomal protein S17 / 30S ribosomal protein S14 type Z / 30S ribosomal protein S8 / Small ribosomal subunit protein uS5 / Small ribosomal subunit protein bTHX / Small ribosomal subunit protein uS15 / Small ribosomal subunit protein bS16 / Small ribosomal subunit protein bS6 / Small ribosomal subunit protein bS18
Similarity search - Component
Biological speciesThermus thermophilus (bacteria)
MethodX-RAY DIFFRACTION / SYNCHROTRON / FOURIER SYNTHESIS / Resolution: 3.297 Å
AuthorsDemirci, H. / Murphy IV, F. / Murphy, E. / Gregory, S.T. / Dahlberg, A.E. / Jogl, G.
CitationJournal: To be Published
Title: A structural basis for streptomycin resistance
Authors: Demirci, H. / Murphy IV, F. / Murphy, E. / Gregory, S.T. / Dahlberg, A.E. / Jogl, G.
History
DepositionFeb 22, 2012Deposition site: RCSB / Processing site: RCSB
Revision 1.0Feb 27, 2013Provider: repository / Type: Initial release

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

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Assembly

Deposited unit
A: 16S rRNA
B: ribosomal protein S2
C: ribosomal protein S3
D: ribosomal protein S4
E: ribosomal protein S5
F: ribosomal protein S6
G: ribosomal protein S7
H: ribosomal protein S8
I: ribosomal protein S9
J: ribosomal protein S10
K: ribosomal protein S11
L: ribosomal protein S12
M: ribosomal protein S13
N: ribosomal protein S14
O: ribosomal protein S15
P: ribosomal protein S16
Q: ribosomal protein S17
R: ribosomal protein S18
S: ribosomal protein S19
T: ribosomal protein S20
U: ribosomal protein THX
hetero molecules


Theoretical massNumber of molelcules
Total (without water)791,860343
Polymers783,95221
Non-polymers7,908322
Water10,233568
1


  • Idetical with deposited unit
  • defined by author
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Unit cell
Length a, b, c (Å)401.251, 401.251, 176.043
Angle α, β, γ (deg.)90.000, 90.000, 90.000
Int Tables number92
Space group name H-MP41212

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Components

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RNA chain , 1 types, 1 molecules A

#1: RNA chain 16S rRNA /


Mass: 494186.781 Da / Num. of mol.: 1 / Mutation: A915G / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: GenBank: M26923.1

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Ribosomal protein ... , 20 types, 20 molecules BCDEFGHIJKLMNOPQRSTU

#2: Protein ribosomal protein S2 /


Mass: 29317.703 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80371
#3: Protein ribosomal protein S3 /


Mass: 26751.076 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80372
#4: Protein ribosomal protein S4 /


Mass: 24373.447 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80373
#5: Protein ribosomal protein S5 /


Mass: 17583.416 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHQ5
#6: Protein ribosomal protein S6 /


Mass: 11988.753 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SLP8
#7: Protein ribosomal protein S7 /


Mass: 18050.973 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P17291
#8: Protein ribosomal protein S8 /


Mass: 15868.570 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHQ2, UniProt: P0DOY9*PLUS
#9: Protein ribosomal protein S9 /


Mass: 14410.614 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80374
#10: Protein ribosomal protein S10 /


Mass: 11954.968 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHN7
#11: Protein ribosomal protein S11 /


Mass: 13737.868 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80376
#12: Protein ribosomal protein S12 /


Mass: 14966.846 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: F6DEQ7, UniProt: Q5SHN3*PLUS
#13: Protein ribosomal protein S13 /


Mass: 14338.861 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80377
#14: Protein ribosomal protein S14 /


Mass: 7158.725 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHQ1, UniProt: P0DOY6*PLUS
#15: Protein ribosomal protein S15 /


Mass: 10578.407 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SJ76
#16: Protein ribosomal protein S16 /


Mass: 10409.983 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SJH3
#17: Protein ribosomal protein S17 /


Mass: 12324.670 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHP7, UniProt: P0DOY7*PLUS
#18: Protein ribosomal protein S18 /


Mass: 10258.299 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SLQ0
#19: Protein ribosomal protein S19 / 40S ribosomal protein S19


Mass: 10605.464 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHP2
#20: Protein ribosomal protein S20 /


Mass: 11736.143 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80380
#21: Protein/peptide ribosomal protein THX / Ribosome


Mass: 3350.030 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SIH3

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Non-polymers , 3 types, 890 molecules

#22: Chemical...
ChemComp-MG / MAGNESIUM ION


Mass: 24.305 Da / Num. of mol.: 320 / Source method: obtained synthetically / Formula: Mg
#23: Chemical ChemComp-ZN / ZINC ION


Mass: 65.409 Da / Num. of mol.: 2 / Source method: obtained synthetically / Formula: Zn
#24: Water ChemComp-HOH / water / Water


Mass: 18.015 Da / Num. of mol.: 568 / Source method: isolated from a natural source / Formula: H2O

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Experimental details

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Experiment

ExperimentMethod: X-RAY DIFFRACTION / Number of used crystals: 1

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Sample preparation

CrystalDensity Matthews: 4.52 Å3/Da / Density % sol: 72.78 %
Crystal growTemperature: 277 K / Method: hanging drop / pH: 6.5 / Details: MPD, pH 6.5, HANGING DROP, temperature 277K

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Data collection

DiffractionMean temperature: 100 K
Diffraction sourceSource: SYNCHROTRON / Site: APS / Beamline: 24-ID-C / Wavelength: 0.98 Å
DetectorType: ADSC QUANTUM 315 / Detector: CCD / Date: Nov 7, 2010
RadiationMonochromator: Kohzu HLD8-24 / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelengthWavelength: 0.98 Å / Relative weight: 1
ReflectionResolution: 3.297→35 Å / Num. all: 210600 / Num. obs: 210600 / % possible obs: 98.9 % / Observed criterion σ(F): -3 / Observed criterion σ(I): -3 / Redundancy: 3.8 % / Rmerge(I) obs: 0.097 / Χ2: 1.451 / Net I/σ(I): 13.5
Reflection shell
Resolution (Å)Redundancy (%)Rmerge(I) obsNum. unique allΧ2Diffraction-ID% possible all
3.297-3.423.80.731209351199.3
3.42-3.553.80.534210111.071199.7
3.55-3.723.80.375210331.214199.7
3.72-3.913.80.249210801.378199.7
3.91-4.163.80.178210431.447199.6
4.16-4.483.80.131210951.759199.4
4.48-4.933.80.106210771.75199.2
4.93-5.643.80.088211151.792199
5.64-7.093.80.074212161.738198.7
7.09-353.60.05209951.345195

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Processing

Software
NameVersionClassificationNB
DENZOdata reduction
SCALEPACKdata scaling
PHENIXdev_978refinement
PDB_EXTRACT3.1data extraction
HKL-2000data collection
PHENIXdev_978phasing
RefinementMethod to determine structure: FOURIER SYNTHESIS / Resolution: 3.297→34.55 Å / Occupancy max: 1 / Occupancy min: 0.01 / FOM work R set: 0.8562 / SU ML: 0.31 / σ(F): 1.33 / Phase error: 21.24 / Stereochemistry target values: ML
RfactorNum. reflection% reflectionSelection details
Rfree0.2076 10598 5.03 %FROM PDB ENTRY 2VQE
Rwork0.1632 ---
obs0.1654 210495 98.35 %-
all-210495 --
Solvent computationShrinkage radii: 0.83 Å / VDW probe radii: 1.1 Å / Solvent model: FLAT BULK SOLVENT MODEL / Bsol: 79.232 Å2 / ksol: 0.266 e/Å3
Displacement parametersBiso max: 488.46 Å2 / Biso mean: 131.6245 Å2 / Biso min: 35.19 Å2
Baniso -1Baniso -2Baniso -3
1--4.1015 Å2-0 Å20 Å2
2---4.1015 Å20 Å2
3---13.9121 Å2
Refinement stepCycle: LAST / Resolution: 3.297→34.55 Å
ProteinNucleic acidLigandSolventTotal
Num. atoms19088 32508 322 568 52486
Refine LS restraints
Refine-IDTypeDev idealNumber
X-RAY DIFFRACTIONf_bond_d0.00656509
X-RAY DIFFRACTIONf_angle_d0.97983904
X-RAY DIFFRACTIONf_chiral_restr0.06710413
X-RAY DIFFRACTIONf_plane_restr0.0054888
X-RAY DIFFRACTIONf_dihedral_angle_d17.99726123
LS refinement shell

Refine-ID: X-RAY DIFFRACTION / Total num. of bins used: 30

Resolution (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkNum. reflection all% reflection obs (%)
3.297-3.33450.33032970.29045518581582
3.3345-3.37370.32323450.28136666701199
3.3737-3.41480.30953810.273966247005100
3.4148-3.4580.33163530.272767097062100
3.458-3.50340.31073650.253867027067100
3.5034-3.55140.27464050.243966007005100
3.5514-3.6020.27153500.229767287078100
3.602-3.65580.26783420.218867167058100
3.6558-3.71280.24253850.210466597044100
3.7128-3.77360.25173740.194766377011100
3.7736-3.83860.21933150.185868187133100
3.8386-3.90830.24693600.185466607020100
3.9083-3.98340.22013380.176567157053100
3.9834-4.06460.22273770.169666927069100
4.0646-4.15280.20093480.155666907038100
4.1528-4.24920.21733500.152667287078100
4.2492-4.35530.18433700.14636676704699
4.3553-4.47280.18453710.14116701707299
4.4728-4.60410.18883580.13626730708899
4.6041-4.75240.18033170.13426738705599
4.7524-4.92180.18253490.1246709705899
4.9218-5.11820.16583420.12536706704899
5.1182-5.35040.16783520.12356778713099
5.3504-5.63130.19793460.13096710705699
5.6313-5.98240.18423540.13586756711099
5.9824-6.44160.19053330.1426753708699
6.4416-7.08480.19753590.13916775713499
7.0848-8.09850.17673420.13316774711698
8.0985-10.160.18133670.15366697706497
10.16-34.55170.21493530.19386532688591
Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

IDL11 (°2)L12 (°2)L13 (°2)L22 (°2)L23 (°2)L33 (°2)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T11 (Å2)T12 (Å2)T13 (Å2)T22 (Å2)T23 (Å2)T33 (Å2)Origin x (Å)Origin y (Å)Origin z (Å)
10.37780.0615-0.16720.4177-0.04570.47590.0068-0.0062-0.0670.14010.12910.14210.14620.0395-0.13130.72040.16270.14610.6843-0.0051.1588144.037983.7706-11.8822
21.9436-0.51970.10510.6144-0.10030.3295-0.0983-1.04180.50250.39830.2051-0.1568-0.23770.1696-0.091.0304-0.14020.13831.7718-0.65971.3236223.3012129.81059.5594
33.04031.7478-0.63571.2336-0.37560.2205-0.0187-0.2879-0.84190.11270.0711-0.67290.16810.0715-0.05840.97260.12110.05560.9672-0.00751.4818167.044771.8486-25.396
41.66942.71670.35325.8953-0.75331.2724-0.13490.06050.0607-0.89610.7282-1.3172-0.64830.1229-0.49551.79590.1380.45890.68780.16621.4534156.5091157.999-34.0628
58.29640.841-1.83824.43480.57646.8395-0.36950.68550.404-0.7103-0.5939-0.1641-0.11230.00490.90881.53190.04450.28740.91240.12511.7114152.9471150.7995-36.9541
69.02111.53965.27038.34722.84353.68060.2862-1.7355-0.0768-0.1571-0.35691.3042-0.1102-1.59850.12721.11750.03020.65530.86320.04911.9376148.4463160.2722-19.7982
72.8903-2.23841.51095.17483.31797.614-0.4559-0.01560.5192-0.1596-0.09780.1136-0.59520.37460.51541.2095-0.09990.34720.8887-0.09021.5997166.3212163.0523-17.7994
85.14263.12381.89449.819-3.45943.39640.4779-0.66830.54050.4180.7874-0.5974-1.55840.8012-1.21041.0851-0.13290.5471.1297-0.63931.5788174.6416156.6503-6.6757
90.07540-0.00760.09520.02550.0191-0.1282-0.23620.34810.78980.061-0.6144-0.09240.24970.07132.0713-0.85660.48922.4476-0.86943.1332194.086167.07121.6101
106.07324.37032.36443.55520.91252.45920.370.03010.41560.19630.2853-0.1026-0.59150.77-0.66461.18140.01830.47510.8674-0.38661.6094174.36155.7893-11.0226
112.4876-3.61141.26757.2471.07897.16480.2066-0.0539-0.0537-1.43020.2622-0.7897-0.44630.5531-0.43931.28230.02860.64380.681-0.16651.8811157.3248151.9456-23.0003
121.3581-0.44810.26265.44130.89781.48350.01260.15120.4317-0.116-0.0165-0.5654-0.57170.0688-0.03721.8431-0.05010.57630.32470.09821.958158.0607168.0029-20.8748
132.07912.6258-2.9453.6181-4.23545.16510.5763-0.0690.7170.3410.0218-0.0032-0.6391-0.1963-0.58532.5651-0.10190.50521.07760.06943.18163.3095174.8084-22.8705
140.7095-0.4044-0.01450.23070.14181.7251-0.13470.10950.364-0.11360.00740.0513-0.37910.4267-0.06431.3810.03710.21032.0289-1.01631.6111210.3969140.416827.2233
153.74840.5081-3.47374.3765-1.67613.55780.0225-1.17390.66880.2759-0.97790.00180.5258-2.38260.91321.40880.040.07262.3546-0.38981.0221207.2913146.146434.7121
164.83441.969-1.10246.49560.54871.3062-0.1836-0.21230.18120.81650.4084-0.989-0.4511.2303-0.19041.59-0.57560.33912.6656-1.18672.1467193.318143.404744.5744
170.09850.07780.47440.95420.04562.37890.1738-0.27510.15710.70170.107-0.1549-0.20570.0951-0.17971.67390.02570.03143.016-0.89641.0366207.8156141.802646.0178
182.29610.08532.11660.00350.0781.9501-0.7013-1.40511.52521.4399-0.65580.4577-0.478-1.74521.29751.89670.3885-0.12622.3814-0.89231.4853192.9427147.602830.4103
192.489-1.4277-0.71156.1416-0.30381.9116-0.1573-0.4542-0.14350.17080.37540.4753-0.1445-0.698-0.21230.95820.03890.37782.011-0.58811.4144187.4134131.105619.2765
202.07494.3173-1.18079.0842-2.90658.17110.1994-1.04271.98590.91480.0627-0.116-1.08920.2089-0.24981.0542-0.02070.02821.5596-0.83312196.9699145.55329.2632
219.78757.6754-7.6256.2762-6.09555.9798-0.1225-0.583-0.12160.24710.13980.16540.03890.16510.0241.15950.14480.15943.0239-0.48381.2592195.6654127.559123.9033
223.47350.2123-2.56970.0876-0.10142.29720.1248-0.39750.1593-0.549-0.4016-0.7336-0.06380.09160.21590.85830.15780.22282.2735-0.86651.5807195.1773138.811716.6489
236.0732-5.4885-2.90475.67840.36458.58480.5393-0.63330.32450.00480.41090.939-0.35430.1236-1.01791.43690.07350.06841.0293-0.18061.3919154.2314111.950537.9093
248.41131.72251.57124.6005-3.08993.04070.1082-1.08370.87750.4153-0.0844-0.12-0.00910.7653-0.00461.15920.09670.07960.8915-0.18730.7233159.984113.43225.8943
254.9222-1.4153.61245.9911-2.24676.699-0.1240.6983-0.7013-0.1021-0.1183-0.36161.07250.62170.1860.96370.27360.29520.8595-0.25831.344139.3835106.299920.4085
265.4078-1.02782.47836.20161.01234.23570.1395-0.93670.38060.6437-0.14630.7011-0.387-0.4698-0.04951.15010.09450.49210.8761-0.0550.9515133.1141107.732540.1873
272.0311.7882-0.53514.74191.75956.69040.32690.89820.0123-0.0963-0.92720.7306-0.3760.0040.59380.83490.12730.26930.84280.01041.2161147.6501113.378617.7551
288.6904-6.9715-7.80729.31283.81048.6368-0.977-1.73111.01491.02130.70940.51320.1338-0.00430.23890.83980.2377-0.0091.7093-0.52250.9412165.3951125.81647.2525
295.66250.5151-5.62529.80980.57445.71190.3325-0.0771-0.35610.278-0.26880.121-0.5849-0.0701-0.01910.9252-0.06030.24171.5728-0.39621.3609186.0606122.9336-2.7655
304.0351-5.2972-2.80317.88022.11034.7917-0.348-0.611.08910.31850.18660.4737-0.37820.18730.13930.9297-0.15250.19930.8431-0.37271.2199162.7387129.73985.0368
316.8788-5.59574.64874.6934-4.57767.5809-0.5477-0.53471.5231.20320.9447-0.3923-1.20270.1393-0.39281.2903-0.23180.47090.7808-0.29991.2014168.462133.62325.7808
324.68926.016-0.57497.7286-0.81312.76370.6972-0.67691.96740.2146-0.23111.4169-0.8088-0.1628-0.53640.86730.21210.22540.9331-0.10521.2737146.0255129.30741.1143
336.77871.3658-6.32395.0999-1.47598.9419-0.54520.1566-0.2415-0.30340.281-0.31040.3225-0.42130.24860.77520.20170.27860.6433-0.06431.1064148.7333117.8754-2.2575
349.3220.91273.24633.9232.76034.2332-0.6284-0.618-1.0680.66250.32650.09180.7945-0.07740.27980.70530.02340.20890.5935-0.00690.7994152.6684118.59642.6025
354.6519-6.1457-0.81588.13831.08150.14410.16770.33290.4932-0.02890.0363-0.2281-0.38890.7752-0.17680.77150.01130.16790.9405-0.27610.6789155.9045124.977-4.5052
369.6131-6.06256.31044.1751-4.31264.461-0.5285-0.7611.40920.95660.07381.2355-2.0021-1.95410.39241.1620.3540.2390.9369-0.0661.4531136.1347134.2709-8.8072
375.82222.6848-3.76652.8119-0.2544.8097-0.16290.11910.20410.31060.26610.4108-0.44550.7763-0.07151.36320.097-0.03751.45190.110.7949168.1783116.8235-84.3358
384.91513.8775.4029.23061.97366.78440.07560.55220.0738-0.46890.1058-0.4872-0.08511.5789-0.16181.2397-0.1160.35752.2364-0.35671.947187.5541116.5016-95.8814
395.26622.5591-5.00793.638-1.12378.7006-0.77830.8858-0.0732-1.52160.37860.30720.0719-0.17150.37411.91250.2156-0.20012.0459-0.44550.8068174.1705112.3386-97.936
402.6683-0.4991.73186.814-1.54751.35750.00950.23830.1766-0.53350.23360.2066-0.3165-0.2907-0.23861.53850.22740.13892.18280.13241.177166.1089118.9506-91.0307
414.3467-3.67340.47883.1381-0.4050.0698-0.07460.46110.4027-0.3609-0.1361-0.2321-0.74530.51080.19532.22420.11970.46881.92050.20671.0647184.5327125.9989-88.5252
428.8842-1.15317.39742.2011-2.22556.93890.20041.4687-0.2977-1.88640.0394-2.34810.48751.8037-0.23630.95530.07630.36921.791-0.0961.2953190.5202117.5556-82.8969
433.93971.69123.62827.38210.01036.7499-0.24591.25980.2054-1.32620.08480.2976-0.7509-0.14720.15851.19180.20250.08431.55120.04640.9485172.1626119.0635-88.2096
443.89173.4148-2.273.1752-2.09972.2015-0.1420.4545-3.189-0.01560.0174-0.67772.5828-0.11650.12781.66630.13670.15470.8803-0.16191.4229169.2535106.2035-84.9291
459.74684.2693.70018.0386-2.06614.1167-0.1498-0.1321-0.5898-0.7680.0275-0.74080.53320.95750.1681.19090.1180.35291.6463-0.20950.888178.017112.4428-85.4316
463.00762.38614.14049.03045.38927.324-0.7075-0.03571.3563-0.607-0.10840.4455-1.3401-0.75610.80081.54230.3528-0.20191.66120.85131.7764166.209131.3133-73.2867
477.78717.53-0.55177.5299-0.66210.10770.26510.1552.86770.3964-0.75262.2473-0.6231-0.49010.41240.8686-0.095-0.00681.2993-0.4392.1075217.8955142.8554-23.485
482.9870.4491.98722.7491-2.26575.0588-0.3916-0.29330.50940.28630.18490.2435-0.2795-0.77230.19460.9964-0.10210.45431.0864-0.39751.8812239.7973145.3619-23.028
497.96730.21762.66125.2574-0.23325.6441-0.08780.74481.3547-0.13020.4343-0.9996-1.19781.4795-0.29120.9629-0.23140.22681.1726-0.28211.9825248.1732144.5173-30.8117
509.21783.36048.17269.256.36968.67630.1674-0.31311.12991.1406-1.03851.96141.1743-1.56520.75421.1096-0.18540.25171.6104-0.24661.1618225.773130.4794-38.5903
512.85893.32061.68433.98212.80816.85740.7865-0.46630.07370.89940.00250.28291.1178-0.1035-0.72281.45610.22350.0251.7162-0.0361.3803219.1954123.7943-38.4042
522.15520.56792.22160.87571.09782.6681-0.1656-0.2669-0.73-0.0818-0.19120.25560.2928-0.3970.34830.9596-0.37330.41861.0635-0.22911.9697236.0833134.9656-30.8702
537.1727-5.29594.9865.0196-3.48787.80440.48080.99150.1279-0.57850.0818-0.6933-0.01582.352-0.4120.9386-0.19380.6081.2322-0.32321.9467251.2749134.7369-30.9579
544.20584.37564.17226.35654.3014.1403-0.45062.1765-2.4345-0.76240.1374-0.90981.5180.290.2871.1910.0520.29851.2995-0.49911.3744238.1375128.3358-40.4767
556.8944-2.13642.37557.52460.66935.85310.3157-1.59911.62541.1631-0.07191.0355-0.9775-0.5435-0.29061.681-0.24080.35752.0394-0.29631.9035220.0144125.1145-44.7518
566.69784.0132-0.01887.93-1.8790.63410.2469-0.1423-0.4748-0.41740.3496-0.20390.10710.9904-0.5280.70720.2460.28080.8493-0.04860.7819140.8919123.3243-29.9686
574.21770.23621.07746.16654.38166.19390.16150.00030.1676-0.26720.10930.4534-0.5479-0.6087-0.25120.77250.33320.36350.66420.27331.1671131.8771128.6081-28.3291
584.94331.26514.09273.80421.96043.6355-0.55380.51750.9334-0.1153-0.02810.7431-1.3189-0.29610.53860.83930.07830.19310.60.09591.4061132.5187132.8435-34.2159
593.75251.79250.25544.81330.25261.73110.0995-0.31220.91250.90880.31650.1323-0.234-0.1451-0.40150.80830.20930.20960.75350.0571.0247141.7296126.6219-19.3688
606.43335.59544.29926.55073.47585.8587-0.0031-1.3178-0.40640.8477-0.13820.48220.195-0.36560.12580.80780.18230.38550.76980.08350.9668129.2128116.9715-13.4907
614.5475.8451-1.62827.5186-2.04561.20720.4232-1.36220.37650.1936-0.570.61950.14830.24410.12530.73380.1560.22880.86080.09720.9901127.18118.6834-16.7854
622.92052.054-0.10395.66570.78781.66810.5692-0.41971.17960.29840.02290.276-0.54250.1032-0.4791.4223-0.5120.0951.3599-0.66462.5086242.1135166.046-5.0607
639.64537.17050.27626.6032-1.42652.206-0.2184-0.19411.21420.13130.3052-1.6746-1.6651.1456-0.11231.5299-0.25470.43881.427-0.54022.876250.517155.5019-9.2791
641.8842-1.30541.33311.8486-0.23282.5924-0.0970.02381.0010.3075-0.7864-0.9795-0.57340.65120.87161.2173-0.42710.16471.5136-0.40022.338242.8648164.1349-12.5291
654.78084.30280.12424.6591-0.65342.2129-0.0130.25540.551-0.09990.37810.6415-0.26670.2192-0.28980.9053-0.32940.11341.1557-0.60162.8734237.0897163.7098-9.3262
663.56124.35110.04297.7292-0.22022.2395-0.01670.6070.7918-0.3340.3402-0.6301-0.68250.5629-0.28361.3929-0.37210.36181.5315-0.56953.3491229.802166.6529-15.8906
674.1372-3.2193-0.24713.8208-2.58275.87280.5614-0.25960.48570.5179-0.60371.11670.3307-0.43340.11150.8602-0.36940.1922.0858-0.7991.4345223.8328132.0783-4.0492
680.00240.00330.00330.0052-0.00460.00730.1537-0.12140.5465-0.14190.4316-0.4199-0.2450.7658-0.5441.7308-0.1324-0.02821.6582-0.91942.3287228.1144158.627.5479
690.0924-0.1810.12870.3863-0.25840.2395-0.1457-0.63730.70421.57290.9392-2.2303-1.46590.7891-0.75611.97-0.0292-0.48852.2717-0.97192.207219.482166.594925.7017
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719.45057.45280.4895.87790.38630.0250.1795-0.83780.34631.1779-0.85990.43890.6332-0.25230.5811.2836-0.09040.46772.2131-0.56151.5528224.8699140.692416.2849
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765.42520.08433.94269.2985-5.97426.8258-0.0660.75910.2462-0.35820.5551-0.4561-0.4737-0.262-0.48480.8732-0.08590.37790.8364-0.17441.5559213.4362118.2985-69.2899
772.92271.1823-2.17721.43751.68718.98550.40730.47310.1468-0.37840.234-0.7752-0.0061.5421-0.56670.81330.04650.29130.8059-0.06331.3998217.67114.3146-65.9967
783.08291.82690.38386.471-5.71256.6449-0.1970.2398-0.16810.025-0.4174-1.30280.36340.37680.61340.78620.01920.15571.2946-0.17581.3577220.4561120.0868-61.555
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814.57664.67064.99194.84635.14445.47430.0521-0.1151.142-0.4489-0.5784-1.8822-1.94031.66680.5411.0348-0.38450.15611.06830.30771.8365211.8045129.6587-69.4789
826.72340.37743.2582.9149-3.19365.56571.00461.0662-0.6447-0.0833-0.5266-0.3074-0.31690.5625-0.46180.98940.08420.29240.9202-0.2521.1541194.0128110.2534-57.4229
832.32612.3594-1.93425.43981.0724.6311-0.00270.6572-0.5043-0.15960.1323-0.68320.06610.4915-0.14510.48540.20410.09930.93340.05670.8835145.273199.4371-27.0596
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874.55064.64930.25519.6607-3.60667.24240.51250.6016-0.3663-0.9302-0.9955-1.08640.25160.59980.46180.91770.430.15491.10970.07281.0438174.07978.92418.6109
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1125.8404-0.18653.98561.807-1.35953.6390.1827-0.0607-0.274-0.2476-0.7316-0.43040.28010.4750.51080.74010.15990.2150.75250.07591.0669138.215498.7504-20.9613
1130.4563-1.3746-1.67234.52875.58346.8959-0.3578-0.1299-0.2518-0.01130.7249-0.48820.24690.5085-0.41160.6360.10950.08550.74620.16521.3865128.060885.9648-32.6175
1146.47755.3432-5.7634.4789-5.18477.73630.36230.91070.288-0.38650.50291.35290.4627-0.9094-0.78971.1942-0.0235-0.20491.09760.20211.6533116.454180.1721-45.4729
1158.56574.9276-4.05229.40071.29733.9221-0.03090.17231.5104-0.0636-0.0371-0.1417-1.2941-0.47390.10630.77230.1086-0.04380.77420.331.0279116.669385-34.1236
1161.6033-2.45571.93437.0985-2.02912.8315-0.00770.29650.8260.01080.11390.137-0.6120.3486-0.09160.7885-0.27230.15581.10120.31921.4118.031880.3018-35.6809
1172.4422-3.4161-0.32886.4548-1.89738.72630.13430.06430.2767-0.43720.19850.0510.19710.8341-0.34271.0055-0.14890.11581.0498-0.10271.1432138.096285.9177-44.1832
1186.7809-2.6149-0.55743.07971.58296.4215-0.8813-1.37572.4448-0.53120.1578-0.5216-2.7551-0.59550.69681.86840.1020.61630.9183-0.60352.4391180.5439140.2071-64.0277
1196.70965.42624.29314.95045.29318.6511-0.10430.28350.7066-1.0065-0.5841.1059-1.2245-0.75290.63431.26620.2232-0.07871.64350.31311.4844173.3574132.1098-75.4128
1209.33676.2127.56094.13265.03016.12230.16241.46040.8736-1.77750.2511-1.055-1.98751.0237-0.39791.40690.25020.74711.05820.29421.6227181.7236132.7372-74.3095
1214.8859-3.9919-4.70653.26133.84554.5350.31720.26380.2071-1.21250.1841-2.7374-0.7692.1882-0.4751.11720.00680.21031.4146-0.31511.4111187.069128.2219-65.8579
1228.91543.9032-6.11619.0529-0.38357.33270.3584-1.23910.21840.31750.173-0.42960.06381.4661-0.49371.52940.16080.46081.6147-0.11380.5919178.5878133.7104-60.7435
1235.4597-0.1806-5.38440.49370.1075.31740.7998-0.06780.52790.44370.4420.6672-1.346-1.029-1.16250.99460.11010.27120.93560.06120.9623175.1367124.1961-68.7501
1243.0162.7393.49973.71732.24174.7711-0.06670.06020.0046-0.15990.234-0.60020.23130.8327-0.14371.24180.33080.22721.48340.20331.2359192.5419125.2417-71.4346
1253.84694.1456-3.74194.5293-4.0973.9733-0.95072.0904-0.2998-1.94740.55240.91011.6345-1.61890.36671.54210.3173-0.44522.3017-0.52661.2701252.5937113.743428.0104
1263.2590.8272-0.25511.17881.50722.8036-0.6692-0.80450.12381.0518-0.04610.0944-0.5687-0.3620.62372.0760.1921-0.14443.3008-0.24151.3171252.529101.136242.7792
1271.51750.73462.50870.82151.46684.2850.24940.4724-1.55350.24090.2981-0.98651.09570.9284-0.52312.42330.39150.37062.4889-0.01642.3289252.509489.604940.2043
1280.00850.0607-0.00050.62510.1810.1522-0.4252-0.5310.730.0680.21151.1734-0.5352-1.36310.19271.0268-0.1766-0.30793.5068-0.25131.5769245.1788102.332.3733
1296.06221.626-2.76571.95030.13641.83450.2820.15630.06510.94370.3427-0.47670.10240.3722-0.57741.46490.4557-0.17362.9085-0.34041.9453252.131497.885133.2131
1304.9843-2.3363-0.42881.567-0.84352.3206-0.0621-1.1902-0.48020.1755-0.2079-0.77210.0961.16390.26271.16370.3563-0.13662.4884-0.05211.5254248.738994.957527.5603
1310.05430.5515-0.42788.0053-6.20194.8179-0.13092.80430.7646-1.53470.4751-0.1143-0.1610.1752-0.29171.95520.29130.22792.67010.39831.2193253.5124104.063125.8291
1323.4168-1.39792.36139.71170.42021.8445-0.46930.6638-0.97730.0618-0.2839-0.3778-0.21281.07430.6551.2712-0.04050.06222.1328-0.15831.4706241.82497.06817.8327
1334.45280.8494.75351.16130.96315.0376-0.0539-0.04360.0083-0.08290.23590.39770.16810.2927-0.12331.0454-0.0990.21120.56880.09721.4134113.651342.0481-14.0241
1346.66110.9448-0.2013.7898-2.31525.79310.2401-1.1397-0.47270.1604-0.251.33991.39-0.5210.05660.87220.00370.09840.70990.41651.42100.711845.5909-24.9947
1351.9618-0.11372.85794.84024.33028.38-0.64850.59820.5366-0.2762-0.4550.80870.3158-0.00720.91051.0411-0.34970.08241.14680.55641.884899.669650.8621-34.1057
1367.9029-1.59025.0780.5877-0.23725.5656-0.09480.56620.4460.1728-0.129-0.62910.22751.52160.25240.73360.1234-0.03952.2575-0.76161.8847251.8168124.8932.3391
1375.3249-1.3230.65193.8372-1.80797.83230.2309-1.04260.85610.35980.4208-0.6855-0.79221.1095-0.5961.2857-0.2401-0.24781.6919-0.62211.4685251.9155131.99287.2947
Refinement TLS group
IDRefine-IDRefine TLS-IDSelection detailsAuth asym-IDAuth seq-ID
1X-RAY DIFFRACTION1chain 'A' and (resseq 5:920)A5 - 920
2X-RAY DIFFRACTION2chain 'A' and (resseq 921:1400)A921 - 1400
3X-RAY DIFFRACTION3chain 'A' and (resseq 1401:1544)A0
4X-RAY DIFFRACTION4chain 'B' and (resseq 7:25)B7 - 25
5X-RAY DIFFRACTION5chain 'B' and (resseq 26:43)B26 - 43
6X-RAY DIFFRACTION6chain 'B' and (resseq 44:63)B44 - 63
7X-RAY DIFFRACTION7chain 'B' and (resseq 64:87)B64 - 87
8X-RAY DIFFRACTION8chain 'B' and (resseq 88:121)B88 - 121
9X-RAY DIFFRACTION9chain 'B' and (resseq 122:131)B122 - 131
10X-RAY DIFFRACTION10chain 'B' and (resseq 132:180)B132 - 180
11X-RAY DIFFRACTION11chain 'B' and (resseq 181:207)B181 - 207
12X-RAY DIFFRACTION12chain 'B' and (resseq 208:226)B208 - 226
13X-RAY DIFFRACTION13chain 'B' and (resseq 227:240)B227 - 240
14X-RAY DIFFRACTION14chain 'C' and (resseq 2:50)C2 - 50
15X-RAY DIFFRACTION15chain 'C' and (resseq 51:70)C51 - 70
16X-RAY DIFFRACTION16chain 'C' and (resseq 71:82)C71 - 82
17X-RAY DIFFRACTION17chain 'C' and (resseq 83:101)C83 - 101
18X-RAY DIFFRACTION18chain 'C' and (resseq 102:112)C102 - 112
19X-RAY DIFFRACTION19chain 'C' and (resseq 113:169)C113 - 169
20X-RAY DIFFRACTION20chain 'C' and (resseq 170:182)C170 - 182
21X-RAY DIFFRACTION21chain 'C' and (resseq 183:193)C183 - 193
22X-RAY DIFFRACTION22chain 'C' and (resseq 194:207)C194 - 207
23X-RAY DIFFRACTION23chain 'D' and (resseq 2:34)D2 - 34
24X-RAY DIFFRACTION24chain 'D' and (resseq 35:68)D35 - 68
25X-RAY DIFFRACTION25chain 'D' and (resseq 69:99)D69 - 99
26X-RAY DIFFRACTION26chain 'D' and (resseq 100:194)D100 - 194
27X-RAY DIFFRACTION27chain 'D' and (resseq 195:209)D195 - 209
28X-RAY DIFFRACTION28chain 'E' and (resseq 5:16)E5 - 16
29X-RAY DIFFRACTION29chain 'E' and (resseq 17:27)E17 - 27
30X-RAY DIFFRACTION30chain 'E' and (resseq 28:50)E28 - 50
31X-RAY DIFFRACTION31chain 'E' and (resseq 51:63)E51 - 63
32X-RAY DIFFRACTION32chain 'E' and (resseq 64:79)E64 - 79
33X-RAY DIFFRACTION33chain 'E' and (resseq 80:103)E80 - 103
34X-RAY DIFFRACTION34chain 'E' and (resseq 104:127)E104 - 127
35X-RAY DIFFRACTION35chain 'E' and (resseq 128:141)E128 - 141
36X-RAY DIFFRACTION36chain 'E' and (resseq 142:154)E142 - 154
37X-RAY DIFFRACTION37chain 'F' and (resseq 1:10)F1 - 10
38X-RAY DIFFRACTION38chain 'F' and (resseq 11:15)F11 - 15
39X-RAY DIFFRACTION39chain 'F' and (resseq 16:32)F16 - 32
40X-RAY DIFFRACTION40chain 'F' and (resseq 33:42)F33 - 42
41X-RAY DIFFRACTION41chain 'F' and (resseq 43:47)F43 - 47
42X-RAY DIFFRACTION42chain 'F' and (resseq 48:56)F48 - 56
43X-RAY DIFFRACTION43chain 'F' and (resseq 57:68)F57 - 68
44X-RAY DIFFRACTION44chain 'F' and (resseq 69:81)F69 - 81
45X-RAY DIFFRACTION45chain 'F' and (resseq 82:92)F82 - 92
46X-RAY DIFFRACTION46chain 'F' and (resseq 93:101)F93 - 101
47X-RAY DIFFRACTION47chain 'G' and (resseq 2:11)G2 - 11
48X-RAY DIFFRACTION48chain 'G' and (resseq 12:35)G12 - 35
49X-RAY DIFFRACTION49chain 'G' and (resseq 36:69)G36 - 69
50X-RAY DIFFRACTION50chain 'G' and (resseq 70:78)G70 - 78
51X-RAY DIFFRACTION51chain 'G' and (resseq 79:92)G79 - 92
52X-RAY DIFFRACTION52chain 'G' and (resseq 93:110)G93 - 110
53X-RAY DIFFRACTION53chain 'G' and (resseq 111:129)G111 - 129
54X-RAY DIFFRACTION54chain 'G' and (resseq 130:144)G130 - 144
55X-RAY DIFFRACTION55chain 'G' and (resseq 145:156)G145 - 156
56X-RAY DIFFRACTION56chain 'H' and (resseq 1:19)H1 - 19
57X-RAY DIFFRACTION57chain 'H' and (resseq 20:42)H20 - 42
58X-RAY DIFFRACTION58chain 'H' and (resseq 43:62)H43 - 62
59X-RAY DIFFRACTION59chain 'H' and (resseq 63:95)H63 - 95
60X-RAY DIFFRACTION60chain 'H' and (resseq 96:116)H96 - 116
61X-RAY DIFFRACTION61chain 'H' and (resseq 117:138)H117 - 138
62X-RAY DIFFRACTION62chain 'I' and (resseq 2:32)I2 - 32
63X-RAY DIFFRACTION63chain 'I' and (resseq 33:40)I33 - 40
64X-RAY DIFFRACTION64chain 'I' and (resseq 41:69)I41 - 69
65X-RAY DIFFRACTION65chain 'I' and (resseq 70:88)I70 - 88
66X-RAY DIFFRACTION66chain 'I' and (resseq 89:106)I89 - 106
67X-RAY DIFFRACTION67chain 'I' and (resseq 107:128)I107 - 128
68X-RAY DIFFRACTION68chain 'J' and (resseq 3:12)J3 - 12
69X-RAY DIFFRACTION69chain 'J' and (resseq 13:29)J13 - 29
70X-RAY DIFFRACTION70chain 'J' and (resseq 30:42)J30 - 42
71X-RAY DIFFRACTION71chain 'J' and (resseq 43:49)J43 - 49
72X-RAY DIFFRACTION72chain 'J' and (resseq 50:71)J50 - 71
73X-RAY DIFFRACTION73chain 'J' and (resseq 72:84)J72 - 84
74X-RAY DIFFRACTION74chain 'J' and (resseq 85:94)J85 - 94
75X-RAY DIFFRACTION75chain 'J' and (resseq 95:100)J95 - 100
76X-RAY DIFFRACTION76chain 'K' and (resseq 11:34)K11 - 34
77X-RAY DIFFRACTION77chain 'K' and (resseq 35:52)K35 - 52
78X-RAY DIFFRACTION78chain 'K' and (resseq 53:75)K53 - 75
79X-RAY DIFFRACTION79chain 'K' and (resseq 76:86)K76 - 86
80X-RAY DIFFRACTION80chain 'K' and (resseq 87:99)K87 - 99
81X-RAY DIFFRACTION81chain 'K' and (resseq 100:110)K100 - 110
82X-RAY DIFFRACTION82chain 'K' and (resseq 111:126)K111 - 126
83X-RAY DIFFRACTION83chain 'L' and (resseq 5:12)L5 - 12
84X-RAY DIFFRACTION84chain 'L' and (resseq 13:22)L13 - 22
85X-RAY DIFFRACTION85chain 'L' and (resseq 23:32)L23 - 32
86X-RAY DIFFRACTION86chain 'L' and (resseq 33:69)L33 - 69
87X-RAY DIFFRACTION87chain 'L' and (resseq 70:101)L70 - 101
88X-RAY DIFFRACTION88chain 'L' and (resseq 102:128)L102 - 128
89X-RAY DIFFRACTION89chain 'M' and (resseq 2:14)M2 - 14
90X-RAY DIFFRACTION90chain 'M' and (resseq 15:66)M15 - 66
91X-RAY DIFFRACTION91chain 'M' and (resseq 67:94)M67 - 94
92X-RAY DIFFRACTION92chain 'M' and (resseq 95:119)M95 - 119
93X-RAY DIFFRACTION93chain 'N' and (resseq 2:11)N2 - 11
94X-RAY DIFFRACTION94chain 'N' and (resseq 12:21)N12 - 21
95X-RAY DIFFRACTION95chain 'N' and (resseq 22:31)N22 - 31
96X-RAY DIFFRACTION96chain 'N' and (resseq 32:40)N32 - 40
97X-RAY DIFFRACTION97chain 'N' and (resseq 41:61)N41 - 61
98X-RAY DIFFRACTION98chain 'O' and (resseq 2:49)O2 - 49
99X-RAY DIFFRACTION99chain 'O' and (resseq 50:73)O50 - 73
100X-RAY DIFFRACTION100chain 'O' and (resseq 74:88)O74 - 88
101X-RAY DIFFRACTION101chain 'P' and (resseq 1:8)P1 - 8
102X-RAY DIFFRACTION102chain 'P' and (resseq 9:23)P9 - 23
103X-RAY DIFFRACTION103chain 'P' and (resseq 24:33)P24 - 33
104X-RAY DIFFRACTION104chain 'P' and (resseq 34:52)P34 - 52
105X-RAY DIFFRACTION105chain 'P' and (resseq 53:61)P53 - 61
106X-RAY DIFFRACTION106chain 'P' and (resseq 62:67)P62 - 67
107X-RAY DIFFRACTION107chain 'P' and (resseq 68:76)P68 - 76
108X-RAY DIFFRACTION108chain 'P' and (resseq 77:83)P77 - 83
109X-RAY DIFFRACTION109chain 'Q' and (resseq 2:12)Q2 - 12
110X-RAY DIFFRACTION110chain 'Q' and (resseq 13:17)Q13 - 17
111X-RAY DIFFRACTION111chain 'Q' and (resseq 18:28)Q18 - 28
112X-RAY DIFFRACTION112chain 'Q' and (resseq 29:34)Q29 - 34
113X-RAY DIFFRACTION113chain 'Q' and (resseq 35:45)Q35 - 45
114X-RAY DIFFRACTION114chain 'Q' and (resseq 46:55)Q46 - 55
115X-RAY DIFFRACTION115chain 'Q' and (resseq 56:61)Q56 - 61
116X-RAY DIFFRACTION116chain 'Q' and (resseq 62:81)Q62 - 81
117X-RAY DIFFRACTION117chain 'Q' and (resseq 82:100)Q82 - 100
118X-RAY DIFFRACTION118chain 'R' and (resseq 19:24)R19 - 24
119X-RAY DIFFRACTION119chain 'R' and (resseq 25:36)R25 - 36
120X-RAY DIFFRACTION120chain 'R' and (resseq 37:43)R37 - 43
121X-RAY DIFFRACTION121chain 'R' and (resseq 44:52)R44 - 52
122X-RAY DIFFRACTION122chain 'R' and (resseq 53:59)R53 - 59
123X-RAY DIFFRACTION123chain 'R' and (resseq 60:75)R60 - 75
124X-RAY DIFFRACTION124chain 'R' and (resseq 76:88)R76 - 88
125X-RAY DIFFRACTION125chain 'S' and (resseq 2:12)S2 - 12
126X-RAY DIFFRACTION126chain 'S' and (resseq 13:25)S13 - 25
127X-RAY DIFFRACTION127chain 'S' and (resseq 26:30)S26 - 30
128X-RAY DIFFRACTION128chain 'S' and (resseq 31:40)S31 - 40
129X-RAY DIFFRACTION129chain 'S' and (resseq 41:52)S41 - 52
130X-RAY DIFFRACTION130chain 'S' and (resseq 53:66)S53 - 66
131X-RAY DIFFRACTION131chain 'S' and (resseq 67:71)S67 - 71
132X-RAY DIFFRACTION132chain 'S' and (resseq 72:81)S72 - 81
133X-RAY DIFFRACTION133chain 'T' and (resseq 8:45)T8 - 45
134X-RAY DIFFRACTION134chain 'T' and (resseq 46:75)T46 - 75
135X-RAY DIFFRACTION135chain 'T' and (resseq 76:106)T76 - 106
136X-RAY DIFFRACTION136chain 'U' and (resseq 2:8)U2 - 8
137X-RAY DIFFRACTION137chain 'U' and (resseq 9:25)U9 - 25

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