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Yorodumi- PDB-6h77: E1 enzyme for ubiquitin like protein activation in complex with UBL -
+Open data
-Basic information
Entry | Database: PDB / ID: 6h77 | ||||||
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Title | E1 enzyme for ubiquitin like protein activation in complex with UBL | ||||||
Components |
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Keywords | SIGNALING PROTEIN / Ubiquitin like protein activating enzyme | ||||||
Function / homology | Function and homology information UFM1 activating enzyme activity / protein ufmylation / protein K69-linked ufmylation / megakaryocyte differentiation / regulation of intracellular estrogen receptor signaling pathway / reticulophagy / neuromuscular process / negative regulation of protein import into nucleus / localization / response to endoplasmic reticulum stress ...UFM1 activating enzyme activity / protein ufmylation / protein K69-linked ufmylation / megakaryocyte differentiation / regulation of intracellular estrogen receptor signaling pathway / reticulophagy / neuromuscular process / negative regulation of protein import into nucleus / localization / response to endoplasmic reticulum stress / erythrocyte differentiation / brain development / Antigen processing: Ubiquitination & Proteasome degradation / intracellular membrane-bounded organelle / endoplasmic reticulum membrane / negative regulation of apoptotic process / Golgi apparatus / endoplasmic reticulum / protein homodimerization activity / zinc ion binding / ATP binding / nucleus / cytosol / cytoplasm Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.1 Å | ||||||
Authors | Soudah, N. / Padala, P. / Hassouna, F. / Mashahreh, B. / Lebedev, A.A. / Isupov, M.N. / Cohen-Kfir, E. / Wiener, R. | ||||||
Citation | Journal: J.Mol.Biol. / Year: 2019 Title: An N-Terminal Extension to UBA5 Adenylation Domain Boosts UFM1 Activation: Isoform-Specific Differences in Ubiquitin-like Protein Activation. Authors: Soudah, N. / Padala, P. / Hassouna, F. / Kumar, M. / Mashahreh, B. / Lebedev, A.A. / Isupov, M.N. / Cohen-Kfir, E. / Wiener, R. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 6h77.cif.gz | 334 KB | Display | PDBx/mmCIF format |
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PDB format | pdb6h77.ent.gz | 268.9 KB | Display | PDB format |
PDBx/mmJSON format | 6h77.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/h7/6h77 ftp://data.pdbj.org/pub/pdb/validation_reports/h7/6h77 | HTTPS FTP |
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-Related structure data
Related structure data | 6h78SC S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Component-ID: 0 / Refine code: 0
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