+
Open data
-
Basic information
Entry | Database: PDB / ID: 6d9o | ||||||
---|---|---|---|---|---|---|---|
Title | NMR solution structure of tamapin, mutant E25A | ||||||
![]() | Potassium channel toxin alpha-KTx 5.4 | ||||||
![]() | ![]() | ||||||
Function / homology | Scorpion short toxins signature. / Scorpion short chain toxin, potassium channel inhibitor / Scorpion short toxin, BmKK2 / ![]() ![]() ![]() | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() | ||||||
![]() | del Rio Portilla, F. / Melchor Meneses, C.M. / Titaux Delgado, G.A. / Mayorga Flores, M. | ||||||
![]() | ![]() Title: Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells Authors: Flores, M. / Chantome, A. / Melchor-Meneses, C.M. / Domingo, I. / Titaux Delgado, G.A. / Galindo-Murillo, R. / Vandier, C. / del Rio Portilla, F. | ||||||
History |
|
-
Structure visualization
Structure viewer | Molecule: ![]() ![]() |
---|
-
Downloads & links
-
Download
PDBx/mmCIF format | ![]() | 181.2 KB | Display | ![]() |
---|---|---|---|---|
PDB format | ![]() | 154.7 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
---|
-Related structure data
Related structure data | ![]() 6d3tC ![]() 6d8hC ![]() 6d8qC ![]() 6d8rC ![]() 6d8sC ![]() 6d8tC ![]() 6d8uC ![]() 6d8yC ![]() 6d93C ![]() 6d9pC C: citing same article ( |
---|---|
Similar structure data | |
Other databases |
|
-
Links
-
Assembly
Deposited unit | ![]()
| |||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 |
| |||||||||
NMR ensembles |
|
-
Components
#1: Protein/peptide | Mass: 3412.150 Da / Num. of mol.: 1 / Mutation: E25A Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() Production host: ![]() ![]() ![]() |
---|
-Experimental details
-Experiment
Experiment | Method: ![]() | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NMR experiment |
|
-
Sample preparation
Details | Type: solution Contents: 1.8 mM Potassium channel toxin alpha_KTx 5.4, 95% H2O/5% D2O Label: 1H_sample / Solvent system: 95% H2O/5% D2O |
---|---|
Sample | Conc.: 1.8 mM / Component: Potassium channel toxin alpha_KTx 5.4 / Isotopic labeling: natural abundance |
Sample conditions | Ionic strength: 0 Not defined / Label: 1 / pH: 6.8 / Pressure: 1 atm / Temperature: 298 K |
-NMR measurement
NMR spectrometer | Type: Varian INOVA / Manufacturer: Varian / Model![]() |
---|
-
Processing
NMR software |
| ||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Refinement | Method: ![]() | ||||||||||||||||||||||||
NMR representative | Selection criteria: lowest energy | ||||||||||||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 200 / Conformers submitted total number: 20 |