登録情報 | データベース: PDB / ID: 5ftu |
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タイトル | Tetrameric complex of Latrophilin 3, Unc5D and FLRT2 |
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要素 | - ADHESION G PROTEIN-COUPLED RECEPTOR L3
- LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2
- NETRIN RECEPTOR UNC5D
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キーワード | SIGNALING PROTEIN / SIGNALLING PROTEIN / LEUCINE-RICH REPEAT (ロイシンリッチリピート) / LRR / UNC5 / APOPTOSIS (アポトーシス) / UNCOORDINATED-5 / NETRIN RECEPTOR / FLRT / LATROPHILIN / ADHESION (接着) / REPULSION / GUIDANCE / BETA PROPELLOR / IMMUNOGLOBULIN (抗体) / THROMBOSPONDIN / OLFACTOMEDIN / LECTIN (レクチン) / TETRAMER (四量体) |
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機能・相同性 | 機能・相同性情報
cell adhesion involved in heart morphogenesis / Downstream signaling of activated FGFR1 / netrin receptor activity / locomotion involved in locomotory behavior / regulation of neuron migration / basement membrane organization / maintenance of postsynaptic specialization structure / cell-cell adhesion via plasma-membrane adhesion molecules / fibroblast growth factor receptor binding / pyramidal neuron differentiation ...cell adhesion involved in heart morphogenesis / Downstream signaling of activated FGFR1 / netrin receptor activity / locomotion involved in locomotory behavior / regulation of neuron migration / basement membrane organization / maintenance of postsynaptic specialization structure / cell-cell adhesion via plasma-membrane adhesion molecules / fibroblast growth factor receptor binding / pyramidal neuron differentiation / chemorepellent activity / positive regulation of synapse assembly / fibroblast growth factor receptor signaling pathway / heart morphogenesis / synapse assembly / response to cocaine / 軸索誘導 / G protein-coupled receptor activity / synapse organization / neuron migration / Schaffer collateral - CA1 synapse / adenylate cyclase-activating G protein-coupled receptor signaling pathway / cell-cell junction / postsynaptic membrane / carbohydrate binding / cell surface receptor signaling pathway / neuron projection / 神経繊維 / focal adhesion / シナプス / glutamatergic synapse / apoptotic process / calcium ion binding / endoplasmic reticulum membrane / 細胞膜 / extracellular space / 細胞膜類似検索 - 分子機能 UNC5D, Death domain / UPA domain / Netrin receptor UNC5 / UPA domain / GPCR, family 2, latrophilin, C-terminal / GPCR, family 2, latrophilin / Latrophilin Cytoplasmic C-terminal region / Leucine rich repeat C-terminal domain / D-galactoside/L-rhamnose binding SUEL lectin domain superfamily / GAIN domain, N-terminal ...UNC5D, Death domain / UPA domain / Netrin receptor UNC5 / UPA domain / GPCR, family 2, latrophilin, C-terminal / GPCR, family 2, latrophilin / Latrophilin Cytoplasmic C-terminal region / Leucine rich repeat C-terminal domain / D-galactoside/L-rhamnose binding SUEL lectin domain superfamily / GAIN domain, N-terminal / GPCR-Autoproteolysis INducing (GAIN) domain / D-galactoside/L-rhamnose binding SUEL lectin domain / ガラクトース結合性レクチンドメイン / SUEL-type lectin domain profile. / Olfactomedin-like domain / Olfactomedin-like domain / Olfactomedin-like domain profile. / Olfactomedin-like domains / Domain present in ZO-1 and Unc5-like netrin receptors / ZU5 domain / ZU5 domain / ZU5 domain profile. / GAIN domain superfamily / GPCR proteolysis site, GPS, motif / GPS motif / GPS domain profile. / G-protein-coupled receptor proteolytic site domain / Leucine-rich repeat N-terminal domain / Leucine rich repeat N-terminal domain / Thrombospondin type 1 domain / Thrombospondin type-1 (TSP1) repeat superfamily / Thrombospondin type-1 (TSP1) repeat profile. / Thrombospondin type 1 repeats / Thrombospondin type-1 (TSP1) repeat / DEATH domain, found in proteins involved in cell death (apoptosis). / Death domain / Cysteine-rich flanking region, C-terminal / Leucine rich repeat C-terminal domain / Death domain / Hormone receptor domain / GPCR, family 2, extracellular hormone receptor domain / G-protein coupled receptors family 2 profile 1. / Domain present in hormone receptors / GPCR family 2, extracellular hormone receptor domain superfamily / G-protein coupled receptors family 2 signature 2. / GPCR, family 2, secretin-like, conserved site / GPCR, family 2, secretin-like / 7 transmembrane receptor (Secretin family) / GPCR, family 2-like / G-protein coupled receptors family 2 profile 2. / ロイシンリッチリピート / Leucine-rich repeat, typical subtype / Leucine-rich repeats, typical (most populated) subfamily / Immunoglobulin I-set / Immunoglobulin I-set domain / Death-like domain superfamily / ロイシンリッチリピート / フィブロネクチンIII型ドメイン / Immunoglobulin subtype 2 / Immunoglobulin C-2 Type / Fibronectin type-III domain profile. / Leucine-rich repeat domain superfamily / Fibronectin type III / Fibronectin type III superfamily / Immunoglobulin subtype / 抗体 / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulin-like fold類似検索 - ドメイン・相同性 Netrin receptor UNC5D / Adhesion G protein-coupled receptor L3 / Leucine-rich repeat transmembrane protein FLRT2類似検索 - 構成要素 |
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生物種 | RATTUS NORVEGICUS (ドブネズミ) MUS MUSCULUS (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 6.01 Å |
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データ登録者 | Jackson, V.A. / Mehmood, S. / Chavent, M. / Roversi, P. / Carrasquero, M. / del Toro, D. / Seyit-Bremer, G. / Ranaivoson, F.M. / Comoletti, D. / Sansom, M.S.P. ...Jackson, V.A. / Mehmood, S. / Chavent, M. / Roversi, P. / Carrasquero, M. / del Toro, D. / Seyit-Bremer, G. / Ranaivoson, F.M. / Comoletti, D. / Sansom, M.S.P. / Robinson, C.V. / Klein, R. / Seiradake, E. |
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引用 | ジャーナル: Nat.Commun. / 年: 2016 タイトル: Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors 著者: Jackson, V.A. / Mehmood, S. / Chavent, M. / Roversi, P. / Carrasquero, M. / Del Toro, D. / Seyit-Bremer, G. / Ranaivoson, F.M. / Comoletti, D. / Sansom, M.S.P. / Robinson, C.V. / Klein, R. / Seiradake, E. |
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履歴 | 登録 | 2016年1月15日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2016年5月4日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2016年5月11日 | Group: Other |
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改定 1.2 | 2020年7月29日 | Group: Advisory / Data collection ...Advisory / Data collection / Derived calculations / Other / Structure summary カテゴリ: chem_comp / entity ...chem_comp / entity / pdbx_chem_comp_identifier / pdbx_database_status / pdbx_entity_nonpoly / pdbx_struct_conn_angle / pdbx_unobs_or_zero_occ_residues / struct_conn / struct_site / struct_site_gen Item: _chem_comp.name / _chem_comp.type ..._chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_database_status.status_code_sf / _pdbx_entity_nonpoly.name / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_comp_id / _pdbx_struct_conn_angle.ptnr2_auth_seq_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr2_label_atom_id / _pdbx_struct_conn_angle.ptnr2_label_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id 解説: Carbohydrate remediation / Provider: repository / タイプ: Remediation |
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改定 1.3 | 2024年1月10日 | Group: Advisory / Data collection ...Advisory / Data collection / Database references / Refinement description / Structure summary カテゴリ: chem_comp / chem_comp_atom ...chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_unobs_or_zero_occ_residues Item: _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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