登録情報 | データベース: PDB / ID: 3kio |
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タイトル | mouse RNase H2 complex |
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要素 | - Ribonuclease H2 subunit A
- Ribonuclease H2 subunit B
- Ribonuclease H2 subunit C
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キーワード | HYDROLASE (加水分解酵素) / ribonuclease (リボヌクレアーゼ) / Aicardi-Goutieres syndrome / RNase H2 / protein complex (タンパク質複合体) / autoimmune disease / Endonuclease (エンドヌクレアーゼ) / Metal-binding / Nuclease (ヌクレアーゼ) / Nucleus (Nucleus) / Phosphoprotein / Acetylation (アセチル化) |
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機能・相同性 | 機能・相同性情報
ribonucleotide metabolic process / ribonuclease H2 complex / DNA replication, removal of RNA primer / regulation of DNA damage checkpoint / RNA catabolic process / リボヌクレアーゼH / DNAミスマッチ修復 / regulation of G2/M transition of mitotic cell cycle / positive regulation of fibroblast proliferation / RNA-DNA hybrid ribonuclease activity ...ribonucleotide metabolic process / ribonuclease H2 complex / DNA replication, removal of RNA primer / regulation of DNA damage checkpoint / RNA catabolic process / リボヌクレアーゼH / DNAミスマッチ修復 / regulation of G2/M transition of mitotic cell cycle / positive regulation of fibroblast proliferation / RNA-DNA hybrid ribonuclease activity / 遺伝子発現 / fibroblast proliferation / in utero embryonic development / negative regulation of gene expression / RNA binding / 核質 / metal ion binding / 細胞核 / 細胞質基質類似検索 - 分子機能 Lipocalin - #680 / Ribonuclease H2, subunit C / Ribonuclease H2 non-catalytic subunit (Ylr154p-like) / Ribonuclease H2 subunit B, wHTH domain / Ribonuclease H2 subunit B / Rnh202, triple barrel domain / Ydr279p protein family (RNase H2 complex component) wHTH domain / Ydr279p protein triple barrel domain / Ribonuclease hii. Domain 2 / Ribonuclease H2, subunit A ...Lipocalin - #680 / Ribonuclease H2, subunit C / Ribonuclease H2 non-catalytic subunit (Ylr154p-like) / Ribonuclease H2 subunit B, wHTH domain / Ribonuclease H2 subunit B / Rnh202, triple barrel domain / Ydr279p protein family (RNase H2 complex component) wHTH domain / Ydr279p protein triple barrel domain / Ribonuclease hii. Domain 2 / Ribonuclease H2, subunit A / Ribonuclease HII, helix-loop-helix cap domain superfamily / Ribonuclease (RNase) H type-2 domain profile. / Ribonuclease HII/HIII / Ribonuclease HII/HIII domain / Ribonuclease HII / Ribonuclease H-like superfamily/Ribonuclease H / Lipocalin / Nucleotidyltransferase; domain 5 / Arc Repressor Mutant, subunit A / Ribonuclease H superfamily / Ribonuclease H-like superfamily / Βバレル / 2-Layer Sandwich / Orthogonal Bundle / Mainly Beta / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 Ribonuclease H2 subunit B / Ribonuclease H2 subunit C / Ribonuclease H2 subunit A類似検索 - 構成要素 |
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生物種 | Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 多波長異常分散 / 解像度: 2.9 Å |
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データ登録者 | Shaban, N. / Harvey, S. / Perrino, F.W. / Hollis, T. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2010 タイトル: The structure of the mammalian RNase H2 complex provides insight into RNA:DNA hybrid processing to prevent immune dysfunction. 著者: Shaban, N.M. / Harvey, S. / Perrino, F.W. / Hollis, T. |
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履歴 | 登録 | 2009年11月2日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2009年11月17日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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