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- PDB-3hfa: Crystal Structure of Mycobacterium Tuberculosis Proteasome open-g... -

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基本情報

登録情報
データベース: PDB / ID: 3hfa
タイトルCrystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant
要素
  • Proteasome (Alpha subunit) PrcA
  • Proteasome (Beta subunit) PrcB
キーワードHYDROLASE (加水分解酵素) / Mycobacterium tuberculosis (結核菌) / Proteasome Endopeptidase / open gate / mutant (ミュータント (人類)) / Proteasome (プロテアソーム)
機能・相同性
機能・相同性情報


symbiont-mediated perturbation of host defenses / 細胞壁 / proteasome endopeptidase complex / proteasome core complex, beta-subunit complex / proteasome core complex, alpha-subunit complex / threonine-type endopeptidase activity / proteasomal protein catabolic process / peptidoglycan-based cell wall / proteolysis involved in protein catabolic process / modification-dependent protein catabolic process ...symbiont-mediated perturbation of host defenses / 細胞壁 / proteasome endopeptidase complex / proteasome core complex, beta-subunit complex / proteasome core complex, alpha-subunit complex / threonine-type endopeptidase activity / proteasomal protein catabolic process / peptidoglycan-based cell wall / proteolysis involved in protein catabolic process / modification-dependent protein catabolic process / proteasome-mediated ubiquitin-dependent protein catabolic process / 細胞膜 / 細胞質基質 / 細胞質
類似検索 - 分子機能
Proteasome, alpha subunit, bacterial / Proteasome subunit beta, actinobacteria / Aminohydrolase, N-terminal nucleophile (Ntn) domain / Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 / Proteasome alpha-type subunit / Proteasome alpha-type subunit profile. / Proteasome B-type subunit / Proteasome beta-type subunit profile. / Proteasome subunit / Proteasome, subunit alpha/beta ...Proteasome, alpha subunit, bacterial / Proteasome subunit beta, actinobacteria / Aminohydrolase, N-terminal nucleophile (Ntn) domain / Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 / Proteasome alpha-type subunit / Proteasome alpha-type subunit profile. / Proteasome B-type subunit / Proteasome beta-type subunit profile. / Proteasome subunit / Proteasome, subunit alpha/beta / Nucleophile aminohydrolases, N-terminal / 4-Layer Sandwich / Alpha Beta
類似検索 - ドメイン・相同性
N,N-ジメチルホルムアミド / Proteasome subunit alpha / Proteasome subunit beta / Proteasome subunit alpha
類似検索 - 構成要素
生物種Mycobacterium tuberculosis (結核菌)
手法X線回折 / シンクロトロン / 分子置換 / 解像度: 2.504 Å
データ登録者Li, D. / Li, H.
引用ジャーナル: Nature / : 2009
タイトル: Inhibitors selective for mycobacterial versus human proteasomes.
著者: Lin, G. / Li, D. / de Carvalho, L.P. / Deng, H. / Tao, H. / Vogt, G. / Wu, K. / Schneider, J. / Chidawanyika, T. / Warren, J.D. / Li, H. / Nathan, C.
履歴
登録2009年5月11日登録サイト: RCSB / 処理サイト: RCSB
改定 1.02009年9月15日Provider: repository / タイプ: Initial release
改定 1.12011年7月13日Group: Version format compliance
改定 1.22019年7月24日Group: Data collection / Refinement description / カテゴリ: software
Item: _software.classification / _software.name / _software.version
改定 1.32023年9月6日Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description
カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim / struct_ref_seq_dif / struct_site
Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
改定 1.42023年11月29日Group: Database references / カテゴリ: pdbx_database_related / Item: _pdbx_database_related.db_name

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構造の表示

構造ビューア分子:
MolmilJmol/JSmol

ダウンロードとリンク

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集合体

登録構造単位
H: Proteasome (Beta subunit) PrcB
C: Proteasome (Beta subunit) PrcB
E: Proteasome (Beta subunit) PrcB
G: Proteasome (Beta subunit) PrcB
J: Proteasome (Beta subunit) PrcB
L: Proteasome (Beta subunit) PrcB
N: Proteasome (Beta subunit) PrcB
P: Proteasome (Beta subunit) PrcB
R: Proteasome (Beta subunit) PrcB
T: Proteasome (Beta subunit) PrcB
V: Proteasome (Beta subunit) PrcB
X: Proteasome (Beta subunit) PrcB
Z: Proteasome (Beta subunit) PrcB
2: Proteasome (Beta subunit) PrcB
D: Proteasome (Alpha subunit) PrcA
A: Proteasome (Alpha subunit) PrcA
B: Proteasome (Alpha subunit) PrcA
F: Proteasome (Alpha subunit) PrcA
I: Proteasome (Alpha subunit) PrcA
K: Proteasome (Alpha subunit) PrcA
M: Proteasome (Alpha subunit) PrcA
O: Proteasome (Alpha subunit) PrcA
Q: Proteasome (Alpha subunit) PrcA
S: Proteasome (Alpha subunit) PrcA
U: Proteasome (Alpha subunit) PrcA
W: Proteasome (Alpha subunit) PrcA
Y: Proteasome (Alpha subunit) PrcA
1: Proteasome (Alpha subunit) PrcA
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)721,68786
ポリマ-717,44728
非ポリマー4,23958
37,9942109
1


  • 登録構造と同一
  • 登録者が定義した集合体
タイプ名称対称操作
identity operation1_555x,y,z1
単位格子
Length a, b, c (Å)119.158, 221.437, 137.120
Angle α, β, γ (deg.)90.00, 104.89, 90.00
Int Tables number4
Space group name H-MP1211
非結晶学的対称性 (NCS)NCSドメイン:
IDEns-ID詳細
11H
21C
31E
41G
51J
61L
71N
81P
91R
101T
111V
121X
131Z
1412
12D
22A
32F
42I
52K
62M
72O
82Q
92S
102U
112W
122Y
1321

NCSドメイン領域:
Dom-IDComponent-IDEns-IDBeg auth comp-IDBeg label comp-IDEnd auth comp-IDEnd label comp-IDSelection detailsAuth asym-IDLabel asym-IDAuth seq-IDLabel seq-ID
111THRTHRSERSERchain H and (resseq 301:522 )HA301 - 5221 - 222
211THRTHRSERSERchain C and (resseq 301:522 )CB301 - 5221 - 222
311THRTHRSERSERchain E and (resseq 301:522 )EC301 - 5221 - 222
411THRTHRSERSERchain G and (resseq 301:522 )GD301 - 5221 - 222
511THRTHRSERSERchain J and (resseq 301:522 )JE301 - 5221 - 222
611THRTHRSERSERchain L and (resseq 301:522 )LF301 - 5221 - 222
711THRTHRSERSERchain N and (resseq 301:522 )NG301 - 5221 - 222
811THRTHRSERSERchain P and (resseq 301:522 )PH301 - 5221 - 222
911THRTHRSERSERchain R and (resseq 301:522 )RI301 - 5221 - 222
1011THRTHRSERSERchain T and (resseq 301:522 )TJ301 - 5221 - 222
1111THRTHRSERSERchain V and (resseq 301:522 )VK301 - 5221 - 222
1211THRTHRSERSERchain X and (resseq 301:522 )XL301 - 5221 - 222
1311THRTHRSERSERchain Z and (resseq 301:522 )ZM301 - 5221 - 222
1411THRTHRSERSERchain 2 and (resseq 301:522 )2N301 - 5221 - 222
112METMETALAALAchain D and (resseq 9:190 or resseq 204:230 )DO9 - 1901 - 182
122GLYGLYLEULEUchain D and (resseq 9:190 or resseq 204:230 )DO204 - 230196 - 222
212METMETALAALAchain A and (resseq 9:190 or resseq 204:230 )AP9 - 1901 - 182
222GLYGLYLEULEUchain A and (resseq 9:190 or resseq 204:230 )AP204 - 230196 - 222
312METMETALAALAchain F and (resseq 9:190 or resseq 204:230 )FR9 - 1901 - 182
322GLYGLYLEULEUchain F and (resseq 9:190 or resseq 204:230 )FR204 - 230196 - 222
412METMETALAALAchain I and (resseq 9:190 or resseq 204:230 )IS9 - 1901 - 182
422GLYGLYLEULEUchain I and (resseq 9:190 or resseq 204:230 )IS204 - 230196 - 222
512METMETALAALAchain K and (resseq 9:190 or resseq 204:230 )KT9 - 1901 - 182
522GLYGLYLEULEUchain K and (resseq 9:190 or resseq 204:230 )KT204 - 230196 - 222
612METMETALAALAchain M and (resseq 9:190 or resseq 204:230 )MU9 - 1901 - 182
622GLYGLYLEULEUchain M and (resseq 9:190 or resseq 204:230 )MU204 - 230196 - 222
712METMETALAALAchain O and (resseq 9:190 or resseq 204:230 )OV9 - 1901 - 182
722GLYGLYLEULEUchain O and (resseq 9:190 or resseq 204:230 )OV204 - 230196 - 222
812METMETALAALAchain Q and (resseq 9:190 or resseq 204:230 )QW9 - 1901 - 182
822GLYGLYLEULEUchain Q and (resseq 9:190 or resseq 204:230 )QW204 - 230196 - 222
912METMETALAALAchain S and (resseq 9:190 or resseq 204:230 )SX9 - 1901 - 182
922GLYGLYLEULEUchain S and (resseq 9:190 or resseq 204:230 )SX204 - 230196 - 222
1012METMETALAALAchain U and (resseq 9:190 or resseq 204:230 )UY9 - 1901 - 182
1022GLYGLYLEULEUchain U and (resseq 9:190 or resseq 204:230 )UY204 - 230196 - 222
1112METMETALAALAchain W and (resseq 9:190 or resseq 204:230 )WZ9 - 1901 - 182
1122GLYGLYLEULEUchain W and (resseq 9:190 or resseq 204:230 )WZ204 - 230196 - 222
1212METMETALAALAchain Y and (resseq 9:190 or resseq 204:230 )YAA9 - 1901 - 182
1222GLYGLYLEULEUchain Y and (resseq 9:190 or resseq 204:230 )YAA204 - 230196 - 222
1312METMETALAALAchain 1 and (resseq 9:190 or resseq 204:230 )1BA9 - 1901 - 182
1322GLYGLYLEULEUchain 1 and (resseq 9:190 or resseq 204:230 )1BA204 - 230196 - 222

NCSアンサンブル:
ID
1
2

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要素

#1: タンパク質
Proteasome (Beta subunit) PrcB / Proteasome / beta subunit


分子量: 25274.264 Da / 分子数: 14 / 由来タイプ: 組換発現
由来: (組換発現) Mycobacterium tuberculosis (結核菌)
遺伝子: MT2170, prcB, Rv2110c / プラスミド: pACYCDuet / 発現宿主: Escherichia coli (大腸菌) / 株 (発現宿主): bl21(de3)
参照: UniProt: O33245, UniProt: P9WHU1*PLUS, proteasome endopeptidase complex
#2: タンパク質
Proteasome (Alpha subunit) PrcA


分子量: 25971.975 Da / 分子数: 14 / 由来タイプ: 組換発現 / 詳細: prcA-prcB-His6
由来: (組換発現) Mycobacterium tuberculosis (結核菌)
遺伝子: prcA, Rv2109c / プラスミド: pACYCDuet / 発現宿主: Escherichia coli (大腸菌) / 株 (発現宿主): bl21(de3)
参照: UniProt: O33244, UniProt: P9WHU1*PLUS, proteasome endopeptidase complex
#3: 化合物...
ChemComp-DMF / DIMETHYLFORMAMIDE / ジメチルホルムアミド / N,N-ジメチルホルムアミド


分子量: 73.094 Da / 分子数: 58 / 由来タイプ: 合成 / : C3H7NO
#4: 水 ChemComp-HOH / water /


分子量: 18.015 Da / 分子数: 2109 / 由来タイプ: 天然 / : H2O

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実験情報

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実験

実験手法: X線回折 / 使用した結晶の数: 1

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試料調製

結晶マシュー密度: 2.44 Å3/Da / 溶媒含有率: 49.52 %
結晶化温度: 277 K / 手法: 蒸気拡散法, シッティングドロップ法 / pH: 5.8
詳細: 13.5% PEG 6000, 60 mM sodium citrate, pH 5.8, 0.1M NaCl, VAPOR DIFFUSION, SITTING DROP, temperature 277K

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データ収集

回折平均測定温度: 100 K
放射光源由来: シンクロトロン / サイト: NSLS / ビームライン: X29A / 波長: 1.0809 Å
検出器タイプ: ADSC QUANTUM 315 / 検出器: CCD / 日付: 2008年4月2日 / 詳細: mirrors
放射モノクロメーター: Si 111 CHANNEL / プロトコル: SINGLE WAVELENGTH / 単色(M)・ラウエ(L): M / 散乱光タイプ: x-ray
放射波長波長: 1.0809 Å / 相対比: 1
反射解像度: 2.5→30 Å / Num. all: 235072 / Num. obs: 229825 / % possible obs: 97.8 % / Observed criterion σ(F): 2 / Observed criterion σ(I): 2 / 冗長度: 5.6 % / Biso Wilson estimate: 46.69 Å2 / Rmerge(I) obs: 0.104 / Net I/σ(I): 9.8
反射 シェル解像度: 2.5→2.59 Å / Rmerge(I) obs: 0.296 / Mean I/σ(I) obs: 1.92 / % possible all: 78.8

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解析

ソフトウェア
名称バージョン分類
PHENIX(phenix.refine)精密化
CNS精密化
CBASSデータ収集
HKL-2000データ削減
HKL-2000データスケーリング
CNS位相決定
精密化構造決定の手法: 分子置換
開始モデル: PDB ENTRY 2FHG
解像度: 2.504→29.864 Å / Occupancy max: 1 / Occupancy min: 1 / SU ML: 2.59 / 交差検証法: THROUGHOUT / σ(F): 1 / 位相誤差: 20.71 / 立体化学のターゲット値: ML
Rfactor反射数%反射Selection details
Rfree0.214 11454 4.98 %RANDOM
Rwork0.173 218332 --
obs0.175 229786 97.77 %-
溶媒の処理減衰半径: 0.9 Å / VDWプローブ半径: 1.11 Å / 溶媒モデル: FLAT BULK SOLVENT MODEL / Bsol: 47.955 Å2 / ksol: 0.337 e/Å3
原子変位パラメータBiso max: 196.58 Å2 / Biso mean: 47.737 Å2 / Biso min: 6 Å2
Baniso -1Baniso -2Baniso -3
1--1.631 Å2-0 Å2-0.501 Å2
2---2.39 Å20 Å2
3---3.317 Å2
精密化ステップサイクル: LAST / 解像度: 2.504→29.864 Å
タンパク質核酸リガンド溶媒全体
原子数46124 0 290 2109 48523
拘束条件
Refine-IDタイプDev ideal
X-RAY DIFFRACTIONf_bond_d0.00647045
X-RAY DIFFRACTIONf_angle_d0.98863603
X-RAY DIFFRACTIONf_chiral_restr0.0947213
X-RAY DIFFRACTIONf_plane_restr0.0038424
X-RAY DIFFRACTIONf_dihedral_angle_d16.14516891
Refine LS restraints NCS
Ens-IDDom-IDAuth asym-IDRefine-IDタイプRms dev position (Å)
11H1638X-RAY DIFFRACTIONPOSITIONAL0.054
12C1638X-RAY DIFFRACTIONPOSITIONAL0.054
13E1638X-RAY DIFFRACTIONPOSITIONAL0.056
14G1638X-RAY DIFFRACTIONPOSITIONAL0.055
15J1638X-RAY DIFFRACTIONPOSITIONAL0.052
16L1638X-RAY DIFFRACTIONPOSITIONAL0.052
17N1638X-RAY DIFFRACTIONPOSITIONAL0.058
18P1638X-RAY DIFFRACTIONPOSITIONAL0.05
19R1638X-RAY DIFFRACTIONPOSITIONAL0.051
110T1638X-RAY DIFFRACTIONPOSITIONAL0.057
111V1638X-RAY DIFFRACTIONPOSITIONAL0.056
112X1638X-RAY DIFFRACTIONPOSITIONAL0.05
113Z1638X-RAY DIFFRACTIONPOSITIONAL0.049
11421638X-RAY DIFFRACTIONPOSITIONAL0.052
21D1614X-RAY DIFFRACTIONPOSITIONAL0.049
22A1614X-RAY DIFFRACTIONPOSITIONAL0.049
23F1614X-RAY DIFFRACTIONPOSITIONAL0.043
24I1614X-RAY DIFFRACTIONPOSITIONAL0.065
25K1614X-RAY DIFFRACTIONPOSITIONAL0.037
26M1614X-RAY DIFFRACTIONPOSITIONAL0.046
27O1607X-RAY DIFFRACTIONPOSITIONAL0.06
28Q1614X-RAY DIFFRACTIONPOSITIONAL0.042
29S1614X-RAY DIFFRACTIONPOSITIONAL0.056
210U1614X-RAY DIFFRACTIONPOSITIONAL0.056
211W1614X-RAY DIFFRACTIONPOSITIONAL0.058
212Y1614X-RAY DIFFRACTIONPOSITIONAL0.049
21311614X-RAY DIFFRACTIONPOSITIONAL0.042
LS精密化 シェル

Refine-ID: X-RAY DIFFRACTION / Total num. of bins used: 30

解像度 (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkNum. reflection all% reflection obs (%)
2.504-2.5330.3423030.2725489579274
2.533-2.5620.3063220.2566613693589
2.562-2.5940.3193650.2476977734293
2.594-2.6260.2833770.2357032740995
2.626-2.6610.2933950.2277195759097
2.661-2.6970.2743850.2227268765398
2.697-2.7360.2853650.2137224758997
2.736-2.7770.2663860.217280766698
2.777-2.820.2744040.1997316772099
2.82-2.8660.2554300.197317774799
2.866-2.9160.263870.1917377776499
2.916-2.9690.253550.1917368772399
2.969-3.0260.2563770.1897363774099
3.026-3.0870.2333690.18374277796100
3.087-3.1540.2314190.18174067825100
3.154-3.2280.2323780.17874347812100
3.228-3.3080.2263700.17474177787100
3.308-3.3980.2213740.17374417815100
3.398-3.4970.2033500.15674497799100
3.497-3.610.1983880.15374347822100
3.61-3.7390.23870.16274017788100
3.739-3.8880.1933820.1574137795100
3.888-4.0650.1774080.14374477855100
4.065-4.2790.1633840.1474497833100
4.279-4.5460.1683740.13274377811100
4.546-4.8950.1583980.1374617859100
4.895-5.3850.1654360.14274207856100
5.385-6.1590.1973800.15474807860100
6.159-7.7370.1694230.14674367859100
7.737-29.8660.153830.1575617944100
精密化 TLS

手法: refined / Refine-ID: X-RAY DIFFRACTION

IDL112)L122)L132)L222)L232)L332)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T112)T122)T132)T222)T232)T332)Origin x (Å)Origin y (Å)Origin z (Å)
1-0.0676-0.02740.02310.016-0.0158-0.03930.57950.83330.0652-0.3249-0.21980.4226-0.1076-0.28170.01350.42010.0584-0.1070.83370.17150.353614.85254.8913-17.9442
20.1734-0.0484-0.13160.44180.13890.02080.22870.26750.83530.2989-0.0135-0.5874-0.305-0.0644-0.06510.2949-0.01920.09610.36080.18930.329940.20154.3839-13.6902
30.27620.3518-0.480.1809-0.1310.7802-0.0136-0.30270.55060.30280.2592-0.33940.08-0.14651.05120.1987-0.11570.05070.19670.2478-0.23534.712747.0124-3.7147
40.1601-0.1862-0.2260.47380.46950.2559-0.06040.086-0.13420.38460.0756-0.25910.60840.01690.03370.2719-0.1410.03360.22830.03090.163437.343629.4981-6.6782
51.57950.5334-0.24670.34710.47930.6151-0.11960.6529-0.124-0.2060.06240.02810.1047-0.3694-0.16580.208-0.10910.00720.45160.11570.024631.323342.9617-14.3092
60.35340.1370.04280.0494-0.09020.1017-0.05240.17220.6003-0.80020.32970.0011-0.1236-0.90530.00350.59060.11930.18480.67080.39260.444837.144255.3992-22.1169
70.2704-0.11210.06110.23810.01390.09830.05120.40580.4888-0.088-0.1739-0.677300.19510.02940.3392-0.07790.06940.53080.29330.388647.979357.049-19.5239
80.21560.0546-0.42860.1563-0.030.14170.0205-0.24160.04990.27340.2664-0.32530.0112-0.1439-0.05050.2588-0.1090.01420.23470.06590.288849.7849.9646-6.4347
90.4967-0.5365-0.35070.3799-0.12770.3717-0.0380.1334-0.0465-0.2463-0.04360.1268-0.20290.0357-0.01030.2857-0.0919-0.05080.19380.04580.107350.682521.772213.5657
100.0607-0.0993-0.33840.9599-0.22640.4155-0.07540.0424-0.0152-0.03090.0042-0.23-0.2675-0.163-0.21190.328-0.0581-0.0650.14660.07760.05139.587236.728311.1933
110.2406-0.3605-0.18450.42990.30121.0331-0.2012-0.0201-0.0053-0.25310.1703-0.0186-0.30070.16550.01430.2325-0.1492-0.02680.1980.03480.101851.140129.609723.0631
120.64370.5062-0.72470.80680.38680.1504-0.00890.1566-0.1666-0.11410.0976-0.3682-0.09440.42410.73720.1688-0.13810.06310.27990.03660.087260.436719.63115.5864
13-0.0291-0.1095-0.04220.15760.10820.0202-0.19180.16050.3259-0.2446-0.1019-0.4144-0.57360.5135-0.01710.4136-0.26370.06040.34460.07590.212367.74619.769612.9846
140.39940.01610.3053-0.10040.41910.5615-0.39460.0238-0.4668-0.1785-0.19760.5108-1.4399-0.45030.0370.70220.112-0.30680.53510.37591.064-23.975555.836412.1957
15-0.0405-0.02340.1293-0.02480.1093-0.0465-0.59130.0858-0.29270.01790.28740.1505-0.5314-0.23970.02750.5760.1732-0.47060.93750.28671.4221-34.986242.260716.4738
160.13830.30460.0166-0.0237-0.01830.1635-0.0925-0.28930.2724-0.31210.079-0.36940.1406-0.39160.00460.25110.0373-0.19510.4970.38690.8785-24.884443.679224.0025
170.0764-0.1327-0.2228-0.0228-0.07060.09530.3548-0.1101-0.6356-0.28090.40850.70580.5746-0.4653-0.01660.3102-0.1358-0.33590.40210.44061.066-19.725240.789316.9917
180.0642-0.2072-0.0012-0.0695-0.07250.0323-0.18-0.20110.181-0.253-0.06940.1620.2448-0.1030.08670.1897-0.0177-0.21790.35490.1060.8545-12.964540.971433.4194
190.0550.0278-0.02080.1209-0.03330.14020.3949-0.10820.1504-0.16240.02090.2573-0.02360.2178-0.04580.2989-0.0745-0.02690.34270.30160.6857-12.94349.513321.0232
200.8054-0.03690.36940.56840.54660.15490.14830.0934-0.0239-0.1760.08540.2623-1.0168-0.6045-0.00150.48320.0721-0.06750.42910.29650.9383-20.193552.253622.8749
210.36940.3535-0.11540.32630.76071.02530.0251-0.00210.2711-0.30610.09810.1329-0.2916-1.315-0.10120.35610.3246-0.18920.96770.4181.2093-36.961150.913525.9996
220.5075-0.5255-0.02120.1432-0.58371.1351-0.05590.1376-0.0527-0.22150.93170.26020.1127-1.6428-0.28160.2953-0.3409-0.18321.35190.69080.6232-28.049533.7673-8.1761
23-0.0736-0.0484-0.0218-0.05190.19860.04640.0172-0.2663-0.1524-0.37390.41760.55580.3897-0.60190.01820.2413-0.3995-0.28991.18830.67620.7746-28.027122.49863.607
240.3582-0.0447-0.14970.1471-0.1529-0.128-0.0386-0.268-0.1287-0.25280.48690.18580.6255-0.7174-0.06710.269-0.2089-0.14010.66970.38150.3807-18.906525.67-0.9369
25-0.00670.0756-0.07710.12720.1051-0.0407-0-0.58560.2336-0.19190.0069-0.2352-0.1355-0.52790.01760.3564-0.2086-0.23351.04840.42550.5331-22.536421.597316.52
260.0172-0.2472-0.28330.1730.14640.3052-0.2240.06830.3143-0.27530.86080.16790.0297-1.2993-0.37540.1542-0.1543-0.1090.88980.30260.4343-21.689134.91571.94
270.12680.04510.00690.31160.06690.18050.4854-0.07290.1983-0.0298-0.45980.15380.5904-0.43720.03050.4269-0.3214-0.13451.61960.67180.6809-37.62926.383710.963
280.0752-0.16680.14370.19470.0855-0.0505-0.6582-0.19580.0713-0.43150.79820.2062-0.5228-1.20780.01020.1801-0.0536-0.12951.61590.78090.7162-38.885635.2662-2.2373
29-0.0271-0.0172-0.02170.06770.08930.05970.4419-0.1101-0.0982-0.3778-0.32840.5772-0.0492-0.1405-0.02860.6091-0.6296-0.65221.67920.91451.2669-45.096126.4976-9.6184
300.8913-0.4448-0.01060.78460.22360.0224-0.1727-0.3762-0.23860.1712-0.0885-0.52220.29830.06640.05740.6377-0.8517-0.40291.51950.89510.623-35.627819.8321-13.1867
31-0.15010.12940.03810.12290.04410.0485-0.0861-0.5074-0.8593-0.2080.42830.60980.29690.1910.03230.7281-0.7806-0.53221.51430.81760.8795-37.31514.9387-1.0698
32-0.19680.99070.24980.6872-0.26430.5153-0.25370.3130.4141-0.16340.56410.7743-0.0836-0.0527-0.07810.1938-0.1348-0.20830.48190.36630.5684-17.6919-2.158720.3501
330.5923-0.7176-0.46320.27460.29160.52440.1094-0.0140.029-0.40160.09740.207-0.00080.04020.06790.409-0.3433-0.3410.55770.39360.4052-13.62943.58546.8365
340.0224-0.1016-0.03120.226-0.1313-0.098-0.46230.25020.1491-0.49830.44320.21360.01880.03480.02590.3603-0.2721-0.25850.55880.21970.3929-8.6961-8.712111.4025
350.48450.56530.85970.38550.34910.4201-0.18670.15920.1493-0.03950.76560.8929-0.5788-0.96651.1299-0.2196-0.364-0.27010.44090.33120.5022-23.554-12.836319.9265
360.0361-0.0210.10740.1147-0.01860.1332-0.01720.38650.136-0.32480.4210.31340.09510.42260.0130.1302-0.1595-0.20590.4440.13880.4698-28.2273-20.983927.8541
370.46680.13820.025-0.44760.2720.24250.0744-0.9176-1.14660.12070.0905-0.00950.3186-0.28330.07260.3174-0.0020.09520.29810.17110.449713.1242-55.174876.6806
380.0264-0.0098-0.04750.0747-0.04560.036-0.5232-0.4319-0.32520.06430.00970.06490.38870.10180.0310.3327-0.00640.06960.5340.03880.24941.6017-43.624783.024
390.3808-0.21590.0192-0.0486-0.00040.0782-0.0852-0.06080.2032-0.14390.0287-0.0259-0.0313-0.20290.00880.23850.040.05550.1513-0.00980.21446.9703-41.777269.3578
400.3804-0.01390.0728-0.01430.02720.2915-0.41040.6575-0.5417-0.61760.2741-0.0290.4057-0.34970.05330.3152-0.07060.12850.2004-0.05610.16933.759-41.328154.0741
410.56990.0322-0.42730.3968-0.52290.7182-0.26050.0268-0.7144-0.24450.1512-0.17210.3268-0.06260.11430.2618-0.03690.12190.1154-0.01330.29579.6172-51.236566.0445
420.00780.0935-0.12590.173-0.23730.1602-0.0244-0.5444-0.8780.1949-0.03530.17530.8493-0.49810.03790.6257-0.17280.13440.39450.18270.7439-3.4136-60.167377.5664
430.08970.08640.07980.16210.05640.0503-0.62-0.18760.2170.01030.22750.3478-0.09530.47510.04180.29060.02580.02380.45710.09490.3356-7.5472-45.237971.2099
440.04050.05970.10240.07430.00190.0259-0.4979-0.7407-0.073-0.04990.54560.0593-0.2875-0.3971-0.02420.3240.23550.11840.64710.01580.2992-10.1476-44.470977.1223
450.202-0.2850.3054-0.0263-0.64770.75930.06690.1133-0.0370.01020.21120.34930.29860.0203-0.17790.1564-0.0007-0.05960.12660.04770.2915-8.7726-20.279750.1843
46-0.0171-0.23930.36820.25410.16970.1154-0.09310.1134-0.09070.17630.1474-0.07610.0670.1747-0.03770.18970.05350.01190.1619-0.02170.1551.8061-24.893665.3467
47-0.05840.28790.02810.7925-0.25390.79740.01060.05220.21230.15250.12520.2623-0.08770.066-0.05280.1254-0.00360.06420.12850.03640.2115-6.656-12.35959.3788
480.86710.062-0.59061.12870.22930.26740.06420.0787-0.013-0.1180.10450.56850.0143-0.2566-0.03560.0527-0.0433-0.03040.1430.11830.4084-20.5532-15.983451.2357
490.12250.1073-0.03460.30020.24341.18960.1115-0.09650.13990.3025-0.20920.1586-0.0237-0.4071-0.14090.1524-0.1666-0.01740.280.24630.5007-27.17-19.443347.1986
500.01-0.05260.00570.06730.01550.04660.3264-0.2997-0.34380.5666-0.1289-0.16690.18610.0360.02970.69190.1410.02450.43220.14990.368854.0005-38.234985.1507
51-0.02440.18680.02220.95290.52620.2542-0.1808-0.03670.13960.01190.132-0.79370.00730.04220.06210.1590.0729-0.04930.17810.00780.301868.4734-20.552572.9742
520.4867-0.22030.21420.1057-0.02610.57710.0655-0.12150.1606-0.1850.0301-0.20080.2844-0.0713-0.09410.17390.0694-0.01610.37760.03490.198153.8231-10.693172.8394
531.0517-0.5365-0.33990.04720.13940.88-0.0075-0.53540.00020.1972-0.2392-0.48050.1110.01040.10910.23690.0466-0.10010.30990.00030.216261.1702-17.211980.0045
540.0812-0.08440.0413-0.03220.0141-0.1459-0.2963-0.43450.35260.6468-0.1404-0.48770.7968-0.40380.05830.62980.197-0.30420.4854-0.01890.647274.2741-20.837787.8359
550.00380.0673-0.13420.6896-0.3130.1953-0.1354-0.11220.42960.2392-0.3195-1.6205-0.01730.57570.15230.19960.0951-0.22040.44130.15940.830981.2236-14.990480.0366
560.04630.05520.0141-0.0183-0.04190.0515-0.50550.27820.2572-0.432-0.224-0.2929-0.07040.32150.07130.24640.0133-0.09630.3132-0.06460.48970.1798-2.841470.2834
570.0762-0.03180.1044-0.0531-0.08540.2018-0.62970.42630.0186-0.6479-0.1215-0.89141.28740.21170.03110.26020.18590.19550.88040.35241.090683.0692-11.949969.5718
58-0.0705-0.0325-0.06760.7345-0.1441-0.1456-0.3550.0937-0.09420.28960.11070.06790.0120.03210.04570.12960.0206-0.0120.17290.00590.17456.375913.736349.5534
59-0.0331-0.0133-0.23030.2751-0.19030.23070.05750.03130.10180.0173-0.08030.0860.02840.039-0.00970.16230.05540.00680.18620.03420.115858.9303-4.705453.6615
600.0374-0.6859-0.14690.83460.47320.28090.01960.1404-0.0896-0.11860.02580.07240.17360.0055-0.02270.04330.0172-0.01310.1971-0.00440.173359.6152-1.406443.0427
61-0.03510.3435-0.6670.88670.32930.0020.02-0.01390.04730.10980.0188-0.0675-0.1193-0.04750.01720.1263-0.0288-0.05540.240.00350.176963.347616.360444.0574
620.3753-0.70590.18870.57810.14110.11230.24010.04350.35830.0801-0.023-0.9327-0.48450.30220.5219-0.0824-0.0424-0.2720.2818-0.09340.18767.222524.229350.0922
630.18260.04030.62870.1990.02990.2998-0.38720.42370.7232-0.0570.09250.2839-0.33290.3184-0.00420.0831-0.0344-0.08490.17030.10750.4542-15.529816.825948.3256
640.3380.4207-0.1380.06360.09290.2556-0.37540.20610.6468-0.29880.16190.4223-0.05120.11320.05630.2241-0.1092-0.29040.24760.28150.7035-18.86424.536631.1581
650.41140.2260.37730.83510.53431.0935-0.17620.12650.1781-0.16550.20540.5298-0.00110.2027-0.160.0588-0.0875-0.11460.25680.18990.4641-18.496513.119832.3227
660.51210.0788-0.07920.23020.6530.0236-0.0689-0.07150.11960.11260.00280.2718-0.0736-0.0348-0.13540.04820.04340.03710.12280.10090.448-22.313911.051150.2888
670.1161-0.18090.1250.25940.16081.0935-0.3311-0.06160.33510.30890.12010.1968-0.0373-0.6419-0.1290.03290.12260.03010.22130.0550.6404-26.319615.136559.0289
68-0.07270.0334-0.10870.32160.11650.1794-0.124-0.2718-0.1546-1.00870.74640.3555-0.07830.2314-0.05350.4255-0.1635-0.12370.37030.15040.1849-10.56739.6421-22.5386
691.467-1.3762-0.56981.41680.71771.30850.6571-0.77970.085-1.30050.1197-0.23310.1302-0.06050.15120.7532-0.3008-0.38320.18170.20140.2573-6.922815.2379-30.1128
700.27510.1584-0.25510.97860.19820.57560.0204-0.2985-0.2488-0.45010.47820.08530.5454-0.42770.36790.3573-0.3442-0.29780.48820.31840.2719-5.305714.4231-13.5884
710.465-0.39-0.02110.3267-0.1380.19470.0108-0.3738-0.0537-0.31470.26240.19080.2217-0.202-0.04580.3088-0.3016-0.19020.46340.24350.1997-9.614125.7825-14.8443
720.2931-0.2210.1250.00480.04340.21480.3675-0.0293-0.42910.2968-0.1928-0.36570.3757-0.4783-0.06410.5189-0.4159-0.39270.51310.33460.5628-18.023814.6027-18.7583
730.8164-1.5714-0.69891.91681.27551.59770.60340.0527-0.2064-1.07270.0648-0.4191-0.2259-0.50010.24840.8521-0.27-0.51440.44410.27290.324-19.871220.2555-33.1517
74-0.0554-0.0840.19770.561-0.03530.34120.7781-0.1042-0.7549-1.4814-0.00270.44430.0323-0.4791-0.09591.4566-0.1136-0.590.19350.07580.4839-12.771711.9352-37.4498
751.2392-0.1646-0.95930.1925-0.15920.32070.7964-0.7878-1.2032-1.1676-0.365-0.19150.26710.6657-0.06431.0406-0.2456-0.47980.2240.190.6887-6.70114.0473-28.6265
76-0.08450.3875-0.08540.4497-0.28950.0573-0.02220.04970.2261-0.28340.24430.38740.3973-0.2303-0.00860.4503-0.227-0.17930.26670.11340.1914.8749-11.5679-1.8905
77-0.0562-0.14040.01640.2939-0.08190.0917-0.04160.04260.1708-0.32070.0180.10170.1858-0.1227-0.00340.3353-0.2485-0.22030.32320.17560.2017.92115.106-9.0597
780.47170.4766-0.0395-0.0003-0.64110.0138-0.23780.1760.0459-0.48010.10160.0765-0.16180.4902-0.00980.5553-0.2071-0.11590.41770.05320.214815.9326-4.0991-6.6573
790.33250.28-0.54690.78620.25320.4255-0.0989-0.0352-0.137-0.43370.12790.16420.402-0.1255-0.41360.5091-0.2777-0.19960.29270.02690.13969.5242-20.6887-5.1163
800.05770.0682-0.0651-0.0412-0.07270.01780.38810.6072-0.4703-0.2961-0.06390.75290.65770.3347-0.05980.9825-0.5077-0.36280.6593-0.00960.42541.5844-27.3047-7.6242
810.70120.1967-0.03750.07670.2625-0.2967-0.2617-0.6694-0.20250.59410.2708-0.06330.2261-0.1209-0.01210.50260.0925-0.01620.36040.09620.160420.4468-32.636795.7423
820.1182-0.0978-0.14010.1220.2112-0.1513-0.1051-0.36420.21450.04580.0764-0.20250.0177-0.0029-0.01590.2608-0.00950.0160.24710.01490.130817.2961-23.575886.4795
830.24660.32830.10910.2473-0.00120.1546-0.05280.14760.04080.0792-0.0496-0.07560.0277-0.09220.01180.2604-0.02840.03590.2242-0.00910.068714.235-29.174278.6498
840.11620.32170.00210.60980.07610.0169-0.2777-0.0017-0.5680.39870.08380.41440.1597-0.0189-0.01080.3405-0.0650.10010.4183-0.00760.19016.2513-27.279188.9241
850.07820.2165-0.330.26910.21890.1896-0.2034-0.1477-0.41440.6703-0.01140.01530.9269-0.35080.02380.5701-0.07870.14130.33470.12580.19811.0747-36.493595.5049
860.05640.06970.0516-0.0733-0.06420.0139-0.2617-0.123-0.14490.66370.3180.48450.1945-0.0931-0.00830.87710.04270.24150.68750.07840.23364.5326-29.0369106.8575
870.6079-0.38340.53331.13280.1190.3481-0.2958-0.08280.3940.89190.2064-0.10460.2285-0.3497-0.04630.5380.1070.08880.42340.08380.0678.7862-18.77698.4877
880.4536-0.20330.27280.366-0.37570.2057-0.0598-0.25440.8010.918-0.1569-0.62960.1179-0.338-0.1150.7297-0.0117-0.00120.4241-0.12690.11119.3546-15.04101.3525
890.1728-0.58140.50490.3046-0.05550.34870.12440.1975-0.08360.20690.14330.41120.01060.00460.03170.10280.04130.04930.16490.0570.2341-0.53284.920269.471
900.384-0.02570.00830.3180.2136-0.02060.06270.1008-0.31660.01210.0859-0.10390.4738-0.25210.00020.18120.02530.02970.16060.02940.21037.5369-2.652673.4156
910.60070.17550.42380.47520.00670.1980.0330.03380.00840.115-0.0362-0.0451-0.0850.07390.00820.15070.00740.01310.15460.01870.079315.9502-0.127276.1294
920.48710.0120.07530.5133-0.3237-0.04460.04870.04880.20130.25840.04980.4088-0.0214-0.0227-0.03150.14370.0470.13730.17870.04580.2256-0.90212.879174.1688
930.46980.73390.07730.65780.6584-0.0223-0.1554-0.80790.77-0.33180.16350.8066-0.5549-0.4492-0.5361-0.0022-0.06090.41360.2370.12940.1827-10.984812.256777.5655
940.5812-0.42580.29470.02960.7149-0.044-0.2753-0.3399-0.15490.64670.2246-0.00990.11450.21860.08660.46980.0755-0.02770.3080.11470.264644.3207-23.765796.626
950.15330.0887-0.00110.24270.05920.0299-0.0301-0.06790.1496-0.1912-0.0792-0.2359-0.07260.01440.040.1350.0004-0.0330.23140.08080.135645.8487-12.144388.0782
960.54910.08360.4704-0.12080.11480.36070.02720.05870.1179-0.0834-0.17390.02290.0495-0.12850.07680.1293-0.00450.01610.23080.05460.11831.3516-13.275484.2315
970.72430.6317-0.08690.5432-0.09390.08120.03110.0103-0.02960.5751-0.1317-0.03210.0721-0.3689-0.01970.26740.05540.01390.27710.06850.145235.6256-15.867794.2788
980.0375-0.03190.0054-0.08140.02530.0330.0314-0.624-0.41540.17370.0547-0.18470.22180.09640.01060.54770.084-0.08610.47930.14470.251343.0589-18.4514106.4338
990.09640.06690.12160.30310.1050.0656-0.4755-0.68010.09511.0990.2033-0.4329-0.3111-0.20980.05750.6376-0.0336-0.2210.49060.04120.355946.3516-8.3819109.5827
100-0.0203-0.06480.003-0.08220.104-0.0665-0.1757-0.26550.53330.39520.0398-0.567-0.2547-0.1947-0.01440.33670.0592-0.15830.30610.0350.26243.1273-0.92794.9629
101-0.0090.0724-0.0659-0.1223-0.00440.0053-0.2520.6715-0.1484-0.17290.376-0.79940.03430.212-0.03010.2894-0.1109-0.23030.31710.0630.58952.43470.2364100.06
1020.4233-0.38250.52660.742-0.4621-0.24520.10130.195-0.4220.2146-0.01890.2173-0.04360.0742-0.00620.1894-0.00670.00050.1670.02520.171630.217919.415370.1318
1030.1149-0.0322-0.1901-0.0246-0.04050.09430.0001-0.23220.00990.2022-0.1226-0.16580.1654-0.4175-0.0060.16710.0071-0.02840.18240.03680.152535.1839.002972.383
1040.03440.2412-0.59040.9654-0.31160.5896-0.0297-0.0803-0.05210.0852-0.1751-0.2025-0.06220.13770.14850.1121-0.012-0.04580.19010.0560.133342.654910.076567.8991
1050.40450.3074-0.27670.34020.46640.35380.0196-0.09630.20460.33640.01020.0822-0.2233-0.01910.01420.2555-0.02230.00430.1598-0.01830.101334.871326.775173.4149
1060.27440.04670.21160.15430.1334-0.1277-0.0764-0.29650.30120.47650.1112-0.0071-0.08080.1876-0.06270.4351-0.01320.01740.2926-0.05530.12631.382732.518277.9018
1070.08070.05190.0424-0.07270.05240.0131-0.12620.79970.27540.3347-0.02170.0989-1.2515-0.1694-0.00560.7719-0.2195-0.39120.60420.46520.8333-0.875466.65974.4836
1080.0333-0.2322-0.00830.50950.04010.35490.0248-0.2580.6253-0.1383-0.05220.4122-0.1383-0.6745-0.11850.37810.0517-0.14030.38370.11750.9621-6.882968.486229.2858
1090.3166-0.2397-0.00180.3229-0.00260.17510.0171-0.00520.2462-0.30490.14020.19380.0169-0.061-0.12620.2056-0.0219-0.06510.15280.14770.41584.930256.205727.3379
1100.43230.06890.1252-0.3491-0.11640.71690.22980.34280.1344-0.0860.50640.1241-0.18760.109-0.08610.32780.0042-0.18910.21920.10860.47742.614961.747224.1051
1110.3080.4622-0.1493-0.01040.11051.33820.67580.19730.5934-0.08830.47440.2045-0.49680.2324-0.07140.3025-0.0578-0.05870.24950.15410.68249.093868.553227.4182
112-0.0702-0.0799-0.17250.05760.00490.32190.7550.42790.4137-0.22970.35610.2012-0.2156-0.868-0.08220.68430.0022-0.16550.2630.14690.8090.125376.038724.9584
113-0.0401-0.0255-0.01710.121-0.0065-0.0178-0.0472-0.14570.8192-0.46350.16790.3921-0.542-0.1721-0.00630.63050.1139-0.02970.38490.06431.0284-1.472480.970934.5682
1140.11070.1013-0.310.16410.2310.221-0.239-0.44890.04930.7370.34820.6041-0.3719-0.5826-0.0880.28630.17120.05550.42870.00960.7157-6.233368.011340.152
1150.6479-0.41810.6510.3105-0.64530.8637-0.11570.3836-0.05430.0640.10480.1912-0.12520.0556-0.07210.07310.01910.02130.0820.05310.250711.137935.773256.7565
1160.30820.4762-0.05110.2985-0.32250.4356-0.06020.10660.083-0.04650.31240.6071-0.0886-0.1007-0.06330.0821-0.0325-0.03720.14070.16410.38630.843441.336741.6948
1170.45560.01230.45120.9247-0.37450.60630.0209-0.04760.07620.02370.34430.5580.0124-0.235-0.11210.05940.01880.03030.11930.08630.4409-2.032532.413949.9426
1180.23260.42970.29371.09710.4280.450.0409-0.14610.09460.3350.07130.2415-0.23910.0281-0.04920.16070.05010.08460.04260.03190.17555.890636.706964.6664
1190.4414-0.16910.58740.1554-0.05610.3315-0.3016-0.7184-0.0250.46340.05380.2038-0.3112-0.53640.10170.37440.07060.02570.152-0.08880.388410.938540.551172.4615
1200.47640.5904-0.0673-0.11460.40590.78420.03650.02010.0466-0.15760.0062-0.01620.0987-0.1020.00660.18480.02440.05180.1016-0.0250.192320.748-59.921853.0019
1210.04260.2054-0.1968-0.0712-0.03120.03380.19630.04110.1707-0.4676-0.15270.29480.1612-0.0335-0.02710.2943-0.04470.1120.10240.01810.259823.7122-48.297134.6253
1220.5741-0.5609-0.2996-0.1048-0.40520.35260.1213-0.0084-0.1513-0.0824-0.0223-0.21040.26740.06040.01230.2228-0.00660.06380.0859-0.03130.247327.3767-59.036246.7492
1230.06620.14620.22910.14560.10450.1216-0.24-0.4483-0.6744-0.00360.0551-0.50650.7697-0.39230.02880.47510.08680.07110.19440.03820.52723.5897-74.908249.871
124-0.00480.026-0.02590.0654-0.11280.1518-0.57240.54330.2164-0.14260.0428-0.0384-0.15190.08450.01440.8948-0.0837-0.20010.43270.03161.038420.6334-79.970740.4914
1250.0082-0.2641-0.12740.07740.00080.0967-0.0005-0.09220.1262-0.3055-0.2677-0.19560.999-0.66970.06910.46-0.08750.06340.3055-0.03710.403410.8573-75.477447.0263
1260.11370.18760.0130.00710.11060.049-0.1162-0.08410.2227-0.2206-0.0198-0.0415-0.2578-0.34020.03440.2590.0169-0.01460.14160.00050.29328.9301-61.579539.547
1270.0021-0.0084-0.01060.05380.02980.01140.1045-0.00440.14530.22980.32220.07410.1780.04470.00380.5262-0.1359-0.02580.36830.08580.35821.9845-72.866345.4687
1280.06180.2923-0.21970.1069-0.16180.1557-0.0728-0.1949-0.0018-0.24830.05470.01370.25580.3075-0.06750.2884-0.1497-0.09490.2350.03140.15773.5454-32.770321.6024
1290.6007-0.1873-0.20820.7665-0.73030.9151-0.19470.00020.0759-0.1590.30550.16430.1058-0.0634-0.07140.2223-0.0357-0.00540.14930.00530.16474.6417-36.227938.5369
1300.010.09360.08770.65960.36110.15350.05290.022-0.0507-0.15380.1171-0.01340.0116-0.0733-0.07020.2748-0.2457-0.1350.28410.09910.2505-10.3975-31.262524.5847
1310.18460.1212-0.25580.1610.47520.0566-0.13320.3372-0.0957-0.33920.19960.16780.1955-0.1352-0.00540.434-0.2381-0.1160.2602-0.01320.1776-0.571-35.82417.9167
1320.0236-0.0106-0.13480.09090.06550.18650.1609-0.21540.1457-0.52930.20950.27790.3387-0.1488-0.02270.7089-0.4042-0.07960.368-0.05350.3912-6.6949-38.703710.6936
133-0.0210.0120.00690.08780.0117-0.05450.7842-0.0324-0.0092-0.8331-0.370.61640.0272-0.0038-0.01540.5635-0.1774-0.1930.51690.14660.38983.300144.3054-24.5915
1341.0056-0.0103-0.25491.01260.12320.38540.08150.13460.0707-0.82910.2523-0.40270.0452-0.12130.14630.6964-0.19120.14710.3106-0.00290.084624.375728.6245-29.5466
1350.5575-0.28060.06140.08820.0432-0.0355-0.09210.0866-0.1381-0.04830.1754-0.27480.1772-0.201-0.09130.2924-0.2091-0.06220.32110.03620.074419.352322.4547-16.8801
1360.0083-0.1098-0.11921.56250.287-0.13150.0143-0.2294-0.1548-0.09340.0940.6270.108-0.3068-0.03360.32-0.1888-0.08760.47770.08610.02469.039229.0264-18.7189
1370.7135-0.00320.56040.17190.1378-0.14340.12220.23550.0149-0.876-0.00010.04160.08140.0058-0.04090.6407-0.2093-0.08010.41290.09470.130614.544523.3519-28.6321
1380.06110.01410.01070.0135-0.0316-0.12210.25730.4560.4318-0.8293-0.25960.0649-0.4492-0.3365-0.05091.38730.0239-0.11820.6940.16450.179716.118930.9621-40.5852
1390.01430.03470.1144-0.01240.04570.00310.53690.1814-0.0728-0.91610.04920.0553-0.02450.0516-0.01331.5509-0.04990.29970.9052-0.09680.383224.947122.9425-44.8284
1400.28040.7704-0.19191.8917-0.00320.802-0.00050.2310.1352-0.7414-0.0519-1.77740.42710.1657-0.04480.7279-0.18270.34390.50020.0180.372431.911623.8639-33.5386
1410.1044-0.268-0.09510.7338-0.66620.2468-0.07990.09410.1459-0.24810.09290.33520.2748-0.10320.01260.3472-0.14860.03850.1794-0.01410.084936.8033-3.7956-4.0938
1420.083-0.0942-0.11230.10550.0134-0.0533-0.2220.2254-0.1233-0.18240.14150.1024-0.1728-0.29520.00610.3865-0.1785-0.01250.33270.02370.219532.67067.2314-6.0772
143-0.03220.57160.21320.91240.45180.1692-0.14480.04860.1114-0.07470.02840.0345-0.0360.03750.05810.2416-0.1221-0.02380.23440.04050.061337.519414.7795-3.9486
144-0.062-0.0702-0.0189-0.31410.10950.56940.19670.2859-1.341-0.39510.06660.31840.36030.16030.69330.2857-0.09660.24130.1747-0.0401-0.760945.9453-4.8783-5.062
1450.04470.0389-0.04270.32250.18780.06130.1952-0.1387-0.6938-0.2395-0.0765-0.85470.26940.10520.24180.5447-0.08780.29550.2758-0.4017-2.024246.1317-12.6705-12.4519
146-0.04470.6456-0.09160.4158-0.52420.40410.50530.38620.6917-0.1372-0.10510.4572-0.36030.1250.58910.29090.3411-0.13860.77430.62310.22612.032464.3129-4.8622
1470.87370.0809-0.2429-0.10530.24950.74730.27280.02710.4742-0.246-0.005-0.0329-0.0633-0.3069-0.21650.2027-0.01470.03330.1160.1290.334224.638764.05216.5673
1480.049-0.2273-0.0612-0.0389-0.10750.89080.216-0.05620.25510.00830.1632-0.5712-0.0054-0.6896-0.05590.3145-0.057-0.01220.11670.01680.229635.827446.384217.13
1491.2724-0.2529-0.32820.45640.12841.38330.2136-0.0290.5301-0.2062-0.034-0.0144-0.163-0.5051-0.1940.26480.02690.06060.11980.22760.236428.01558.9087.3569
150-0.01640.0657-0.07810.04580.22430.09410.41030.27310.3235-0.70970.2909-0.2179-0.5544-0.4722-0.06460.77860.06870.28840.25550.32010.616131.029875.07065.1635
1510.0972-0.0772-0.09650.05910.14420.18830.2816-0.0470.5922-0.11080.2017-0.5223-0.88960.1242-0.03440.5868-0.03770.25670.12970.12880.589733.018778.084416.9771
1520.19610.0133-0.16730.03570.08310.1762-0.0665-0.3014-0.05450.24370.1015-0.63860.17750.182-0.02760.3187-0.07740.02560.09320.06490.466237.910762.016324.6923
1530.0173-0.0259-0.03980.04110.04360.02520.50290.17380.1375-0.02070.1203-0.15170.2003-0.1573-0.03190.4109-0.06580.18720.33090.08680.710230.90376.266827.6949
1540.7086-0.32530.48970.2666-0.30780.06250.1330.3933-0.0748-0.0354-0.28330.0008-0.0285-0.0408-0.00590.1372-0.021-0.03970.18780.04240.150741.684436.636441.2733
1551.3548-0.1065-0.04360.4468-0.314-0.0690.06840.0763-0.10380.00460.02610.2079-0.0390.0327-0.05030.1941-0.0214-0.04110.14480.02010.172326.729643.933436.5015
1560.36720.1522-0.01380.13680.05130.2397-0.0534-0.0520.0119-0.11370.018-0.0807-0.1152-0.12420.01930.1693-0.0327-0.02630.1741-0.02630.203236.947840.892154.4876
1570.42230.2124-0.3098-0.00170.43680.2442-0.0417-0.07530.0052-0.03020.0805-0.1445-0.03250.1793-0.00630.1321-0.0792-0.0460.19160.00240.201646.253940.409745.0745
1580.07660.02690.09570.1381-0.00120.1101-0.1292-0.15040.61070.2999-0.0876-0.4072-0.00290.21230.00050.1813-0.08-0.03620.2239-0.08820.306854.630241.27854.4174
1591.42450.7153-1.05890.3027-0.13140.35580.0922-0.0241-0.89720.6581-0.8094-1.3437-0.04590.19970.05590.49-0.1162-0.08760.17990.14620.297662.3664-47.496968.2825
1600.03330.1118-0.4593-0.04230.06620.7954-0.2628-0.0419-0.4743-0.1307-0.1578-0.3630.35640.08360.23520.20510.03580.130.09140.08380.520472.5492-38.263646.053
1610.41370.3339-0.10080.2210.12670.3176-0.1041-0.0564-0.1223-0.29550.1585-0.41150.0871-0.1051-0.02540.1303-0.00980.00110.1321-0.03250.258561.5091-29.480148.9679
162-0.0397-0.17660.43820.7570.27140.994-0.03430.0096-0.08060.0929-0.1164-0.4107-0.04520.13240.10440.1595-0.0265-0.03640.21290.06730.335167.8873-32.05957.4243
163-0.08650.0520.03640.08230.07040.0059-0.0496-0.4479-0.6508-0.1864-0.3032-0.86560.32620.4404-0.02150.22220.05340.01750.54030.36650.973283.7363-40.355755.6795
1640.53880.29030.38791.39980.78680.3182-0.28090.2312-0.7051-1.1024-0.0703-1.01760.27130.6078-0.03680.24290.160.32330.22570.08010.836381.298-43.924744.9711
165-0.00520.0219-0.00070.03240.0510.0471-0.04210.4490.1085-0.653-0.2746-0.01480.29940.35020.03250.14980.0012-0.00190.3142-0.01280.338674.2887-26.508638.4765
1660.321-0.33580.8764-0.0187-0.21870.60060.2999-0.2707-0.5632-0.9488-0.13670.10770.4192-0.50010.22470.51080.06410.4016-0.0422-0.17150.503879.5089-42.011536.2248
1670.166-0.019-0.37450.1715-0.4020.3697-0.06460.0182-0.06390.2909-0.00280.05840.12720.07580.05480.1686-0.01660.03820.16840.03070.14259.2321-7.536522.9155
1680.1280.0860.20870.16340.13960.10010.0272-0.32670.1308-0.13490.0173-0.3263-0.09390.0920.04060.1654-0.00940.04030.21520.06340.245157.1339-16.747230.3319
1690.92660.58290.50710.7269-0.3018-0.29290.05080.027-0.064-0.0930.0115-0.06480.1319-0.0634-0.00090.16160.02450.06760.1532-0.03070.134453.486-21.820223.4015
1700.35390.1411-0.0240.1053-0.0355-0.0114-0.12840.0898-0.128-0.04790.0324-0.04380.00260.20480.05230.1407-0.04560.09510.26820.00840.167164.0671-7.175515.8811
1710.20830.1197-0.15080.4832-0.34950.0291-0.06430.127-0.1212-0.3213-0.2985-0.71640.27580.2730.06020.1957-0.0480.11110.383-0.04550.272570.8251-7.185814.1901
172-0.18380.8048-0.26560.1722-0.17660.4255-0.2367-0.0974-0.3722-0.022-0.2627-0.20220.90620.65970.0750.32030.07790.1370.21890.03310.489951.5201-60.259750.6269
1730.07370.0605-0.0874-0.14150.03720.02-0.07880.3192-0.4792-0.0449-0.0431-0.27140.1984-0.01110.00790.3822-0.00820.21130.2106-0.09570.50240.3599-64.078437.6234
1740.06320.5798-0.00370.19530.14160.5131-0.13920.0055-0.1504-0.07680.0651-0.27920.0382-0.00430.00810.15180.01170.07930.1318-0.02720.308847.1513-46.721739.6644
1750.76930.240.43490.58670.29540.18390.0029-0.0084-0.1346-0.0341-0.0417-0.3190.25530.27820.00280.16380.04610.14140.1258-0.00810.335354.2109-52.547940.9161
1760.00420.0795-0.0228-0.05650.01930.0487-0.4329-0.4403-0.7307-0.07640.4123-0.11740.2558-0.0013-0.00610.3720.11560.18620.26860.02730.881557.5096-66.400642.2709
1770.57350.397-0.42140.485-0.68420.2338-0.46090.2662-0.534-0.40720.11470.0510.5051-0.01880.1210.42570.07560.19830.1145-0.14310.58653.4249-69.497532.1714
1780.4846-0.08660.12890.066-0.00421.42040.54790.2967-0.0349-0.34750.10940.27870.5012-0.45120.04540.23220.03890.18270.0877-0.06570.312748.2858-52.480323.4001
179-0.00910.03570.0551-0.10170.0209-0.0221-0.71660.1771-0.0819-0.25030.60570.09540.1052-0.67420.03060.3708-0.18550.15330.2487-0.16310.435143.2816-67.317625.5207
180-0.41430.44630.1619-0.0803-0.40940.37870.2776-0.0654-0.05790.044-0.2637-0.08120.11490.0646-0.01710.4127-0.09380.07070.1964-0.0380.184435.4813-28.321710.4718
1810.75340.2920.1980.6507-0.34060.2582-0.0652-0.0332-0.2136-0.30420.0810.02540.03120.07410.00650.2369-0.04960.06060.1075-0.04180.175629.5487-37.54923.8846
1820.4091-0.1232-0.01250.3294-0.05150.00280.1162-0.1498-0.1027-0.34120.01560.03820.0529-0.0622-0.03140.476-0.1559-0.00830.1637-0.08380.101323.3739-33.88574.2779
1830.7429-0.3313-0.22420.3478-0.23830.07880.10720.2342-0.1088-0.5539-0.0364-0.01140.13130.15770.12880.3985-0.10350.09590.173-0.10.076135.3535-30.30953.9564
1840.6608-0.1563-0.3920.20230.46311.0574-0.4832-0.2648-0.9373-0.3499-0.0736-0.22090.27810.4392-0.75090.5035-0.12430.1317-0.0791-0.3620.010937.6878-33.8611-3.6187
精密化 TLSグループ
IDRefine-IDRefine TLS-IDSelection detailsAuth asym-IDAuth seq-ID
1X-RAY DIFFRACTION1(chain 1 and resid 9:23)19 - 23
2X-RAY DIFFRACTION2(chain 1 and resid 24:45)124 - 45
3X-RAY DIFFRACTION3(chain 1 and resid 46:84)146 - 84
4X-RAY DIFFRACTION4(chain 1 and resid 85:97)185 - 97
5X-RAY DIFFRACTION5(chain 1 and resid 98:150)198 - 150
6X-RAY DIFFRACTION6(chain 1 and resid 151:165)1151 - 165
7X-RAY DIFFRACTION7(chain 1 and resid 166:206)1166 - 206
8X-RAY DIFFRACTION8(chain 1 and resid 207:234)1207 - 234
9X-RAY DIFFRACTION9(chain 2 and resid 301:354)2301 - 354
10X-RAY DIFFRACTION10(chain 2 and resid 355:388)2355 - 388
11X-RAY DIFFRACTION11(chain 2 and resid 389:462)2389 - 462
12X-RAY DIFFRACTION12(chain 2 and resid 463:502)2463 - 502
13X-RAY DIFFRACTION13(chain 2 and resid 503:522)2503 - 522
14X-RAY DIFFRACTION14(chain A and resid 9:40)A9 - 40
15X-RAY DIFFRACTION15(chain A and resid 41:51)A41 - 51
16X-RAY DIFFRACTION16(chain A and resid 52:67)A52 - 67
17X-RAY DIFFRACTION17(chain A and resid 68:81)A68 - 81
18X-RAY DIFFRACTION18(chain A and resid 82:97)A82 - 97
19X-RAY DIFFRACTION19(chain A and resid 98:109)A98 - 109
20X-RAY DIFFRACTION20(chain A and resid 110:150)A110 - 150
21X-RAY DIFFRACTION21(chain A and resid 151:234)A151 - 234
22X-RAY DIFFRACTION22(chain B and resid 9:53)B9 - 53
23X-RAY DIFFRACTION23(chain B and resid 54:65)B54 - 65
24X-RAY DIFFRACTION24(chain B and resid 66:84)B66 - 84
25X-RAY DIFFRACTION25(chain B and resid 85:95)B85 - 95
26X-RAY DIFFRACTION26(chain B and resid 96:127)B96 - 127
27X-RAY DIFFRACTION27(chain B and resid 128:140)B128 - 140
28X-RAY DIFFRACTION28(chain B and resid 141:177)B141 - 177
29X-RAY DIFFRACTION29(chain B and resid 178:190)B178 - 190
30X-RAY DIFFRACTION30(chain B and resid 203:211)B203 - 211
31X-RAY DIFFRACTION31(chain B and resid 212:234)B212 - 234
32X-RAY DIFFRACTION32(chain C and resid 301:355)C301 - 355
33X-RAY DIFFRACTION33(chain C and resid 356:422)C356 - 422
34X-RAY DIFFRACTION34(chain C and resid 423:444)C423 - 444
35X-RAY DIFFRACTION35(chain C and resid 445:513)C445 - 513
36X-RAY DIFFRACTION36(chain C and resid 514:522)C514 - 522
37X-RAY DIFFRACTION37(chain D and resid 9:41)D9 - 41
38X-RAY DIFFRACTION38(chain D and resid 42:52)D42 - 52
39X-RAY DIFFRACTION39(chain D and resid 53:84)D53 - 84
40X-RAY DIFFRACTION40(chain D and resid 85:97)D85 - 97
41X-RAY DIFFRACTION41(chain D and resid 98:150)D98 - 150
42X-RAY DIFFRACTION42(chain D and resid 151:205)D151 - 205
43X-RAY DIFFRACTION43(chain D and resid 206:219)D206 - 219
44X-RAY DIFFRACTION44(chain D and resid 220:234)D220 - 234
45X-RAY DIFFRACTION45(chain E and resid 301:357)E301 - 357
46X-RAY DIFFRACTION46(chain E and resid 358:388)E358 - 388
47X-RAY DIFFRACTION47(chain E and resid 389:450)E389 - 450
48X-RAY DIFFRACTION48(chain E and resid 451:503)E451 - 503
49X-RAY DIFFRACTION49(chain E and resid 504:523)E504 - 523
50X-RAY DIFFRACTION50(chain F and resid 9:18)F9 - 18
51X-RAY DIFFRACTION51(chain F and resid 19:79)F19 - 79
52X-RAY DIFFRACTION52(chain F and resid 80:109)F80 - 109
53X-RAY DIFFRACTION53(chain F and resid 110:150)F110 - 150
54X-RAY DIFFRACTION54(chain F and resid 151:169)F151 - 169
55X-RAY DIFFRACTION55(chain F and resid 170:212)F170 - 212
56X-RAY DIFFRACTION56(chain F and resid 213:222)F213 - 222
57X-RAY DIFFRACTION57(chain F and resid 223:234)F223 - 234
58X-RAY DIFFRACTION58(chain G and resid 301:335)G301 - 335
59X-RAY DIFFRACTION59(chain G and resid 336:387)G336 - 387
60X-RAY DIFFRACTION60(chain G and resid 388:434)G388 - 434
61X-RAY DIFFRACTION61(chain G and resid 435:503)G435 - 503
62X-RAY DIFFRACTION62(chain G and resid 504:522)G504 - 522
63X-RAY DIFFRACTION63(chain H and resid 301:335)H301 - 335
64X-RAY DIFFRACTION64(chain H and resid 336:383)H336 - 383
65X-RAY DIFFRACTION65(chain H and resid 384:436)H384 - 436
66X-RAY DIFFRACTION66(chain H and resid 437:503)H437 - 503
67X-RAY DIFFRACTION67(chain H and resid 504:523)H504 - 523
68X-RAY DIFFRACTION68(chain I and resid 9:26)I9 - 26
69X-RAY DIFFRACTION69(chain I and resid 27:54)I27 - 54
70X-RAY DIFFRACTION70(chain I and resid 55:95)I55 - 95
71X-RAY DIFFRACTION71(chain I and resid 96:126)I96 - 126
72X-RAY DIFFRACTION72(chain I and resid 127:150)I127 - 150
73X-RAY DIFFRACTION73(chain I and resid 151:172)I151 - 172
74X-RAY DIFFRACTION74(chain I and resid 173:209)I173 - 209
75X-RAY DIFFRACTION75(chain I and resid 210:234)I210 - 234
76X-RAY DIFFRACTION76(chain J and resid 301:351)J301 - 351
77X-RAY DIFFRACTION77(chain J and resid 352:388)J352 - 388
78X-RAY DIFFRACTION78(chain J and resid 389:434)J389 - 434
79X-RAY DIFFRACTION79(chain J and resid 435:503)J435 - 503
80X-RAY DIFFRACTION80(chain J and resid 504:522)J504 - 522
81X-RAY DIFFRACTION81(chain K and resid 9:53)K9 - 53
82X-RAY DIFFRACTION82(chain K and resid 54:82)K54 - 82
83X-RAY DIFFRACTION83(chain K and resid 83:117)K83 - 117
84X-RAY DIFFRACTION84(chain K and resid 118:135)K118 - 135
85X-RAY DIFFRACTION85(chain K and resid 136:167)K136 - 167
86X-RAY DIFFRACTION86(chain K and resid 168:189)K168 - 189
87X-RAY DIFFRACTION87(chain K and resid 190:219)K190 - 219
88X-RAY DIFFRACTION88(chain K and resid 220:234)K220 - 234
89X-RAY DIFFRACTION89(chain L and resid 301:335)L301 - 335
90X-RAY DIFFRACTION90(chain L and resid 336:354)L336 - 354
91X-RAY DIFFRACTION91(chain L and resid 355:434)L355 - 434
92X-RAY DIFFRACTION92(chain L and resid 435:503)L435 - 503
93X-RAY DIFFRACTION93(chain L and resid 504:522)L504 - 522
94X-RAY DIFFRACTION94(chain M and resid 9:44)M9 - 44
95X-RAY DIFFRACTION95(chain M and resid 45:79)M45 - 79
96X-RAY DIFFRACTION96(chain M and resid 80:112)M80 - 112
97X-RAY DIFFRACTION97(chain M and resid 113:150)M113 - 150
98X-RAY DIFFRACTION98(chain M and resid 151:167)M151 - 167
99X-RAY DIFFRACTION99(chain M and resid 168:205)M168 - 205
100X-RAY DIFFRACTION100(chain M and resid 206:222)M206 - 222
101X-RAY DIFFRACTION101(chain M and resid 223:234)M223 - 234
102X-RAY DIFFRACTION102(chain N and resid 301:335)N301 - 335
103X-RAY DIFFRACTION103(chain N and resid 336:354)N336 - 354
104X-RAY DIFFRACTION104(chain N and resid 355:453)N355 - 453
105X-RAY DIFFRACTION105(chain N and resid 454:503)N454 - 503
106X-RAY DIFFRACTION106(chain N and resid 504:523)N504 - 523
107X-RAY DIFFRACTION107(chain O and resid 10:21)O10 - 21
108X-RAY DIFFRACTION108(chain O and resid 22:53)O22 - 53
109X-RAY DIFFRACTION109(chain O and resid 54:112)O54 - 112
110X-RAY DIFFRACTION110(chain O and resid 113:130)O113 - 130
111X-RAY DIFFRACTION111(chain O and resid 131:150)O131 - 150
112X-RAY DIFFRACTION112(chain O and resid 151:161)O151 - 161
113X-RAY DIFFRACTION113(chain O and resid 162:187)O162 - 187
114X-RAY DIFFRACTION114(chain O and resid 188:234)O188 - 234
115X-RAY DIFFRACTION115(chain P and resid 301:335)P301 - 335
116X-RAY DIFFRACTION116(chain P and resid 336:388)P336 - 388
117X-RAY DIFFRACTION117(chain P and resid 389:444)P389 - 444
118X-RAY DIFFRACTION118(chain P and resid 445:506)P445 - 506
119X-RAY DIFFRACTION119(chain P and resid 507:522)P507 - 522
120X-RAY DIFFRACTION120(chain Q and resid 9:84)Q9 - 84
121X-RAY DIFFRACTION121(chain Q and resid 85:97)Q85 - 97
122X-RAY DIFFRACTION122(chain Q and resid 98:150)Q98 - 150
123X-RAY DIFFRACTION123(chain Q and resid 151:168)Q151 - 168
124X-RAY DIFFRACTION124(chain Q and resid 169:173)Q169 - 173
125X-RAY DIFFRACTION125(chain Q and resid 174:208)Q174 - 208
126X-RAY DIFFRACTION126(chain Q and resid 209:228)Q209 - 228
127X-RAY DIFFRACTION127(chain Q and resid 229:234)Q229 - 234
128X-RAY DIFFRACTION128(chain R and resid 301:335)R301 - 335
129X-RAY DIFFRACTION129(chain R and resid 336:431)R336 - 431
130X-RAY DIFFRACTION130(chain R and resid 432:469)R432 - 469
131X-RAY DIFFRACTION131(chain R and resid 470:505)R470 - 505
132X-RAY DIFFRACTION132(chain R and resid 506:522)R506 - 522
133X-RAY DIFFRACTION133(chain S and resid 9:21)S9 - 21
134X-RAY DIFFRACTION134(chain S and resid 22:64)S22 - 64
135X-RAY DIFFRACTION135(chain S and resid 65:96)S65 - 96
136X-RAY DIFFRACTION136(chain S and resid 97:115)S97 - 115
137X-RAY DIFFRACTION137(chain S and resid 116:150)S116 - 150
138X-RAY DIFFRACTION138(chain S and resid 151:168)S151 - 168
139X-RAY DIFFRACTION139(chain S and resid 169:186)S169 - 186
140X-RAY DIFFRACTION140(chain S and resid 187:234)S187 - 234
141X-RAY DIFFRACTION141(chain T and resid 301:335)T301 - 335
142X-RAY DIFFRACTION142(chain T and resid 336:355)T336 - 355
143X-RAY DIFFRACTION143(chain T and resid 356:434)T356 - 434
144X-RAY DIFFRACTION144(chain T and resid 435:503)T435 - 503
145X-RAY DIFFRACTION145(chain T and resid 504:523)T504 - 523
146X-RAY DIFFRACTION146(chain U and resid 9:23)U9 - 23
147X-RAY DIFFRACTION147(chain U and resid 24:84)U24 - 84
148X-RAY DIFFRACTION148(chain U and resid 85:95)U85 - 95
149X-RAY DIFFRACTION149(chain U and resid 96:148)U96 - 148
150X-RAY DIFFRACTION150(chain U and resid 149:169)U149 - 169
151X-RAY DIFFRACTION151(chain U and resid 170:212)U170 - 212
152X-RAY DIFFRACTION152(chain U and resid 213:223)U213 - 223
153X-RAY DIFFRACTION153(chain U and resid 224:234)U224 - 234
154X-RAY DIFFRACTION154(chain V and resid 301:335)V301 - 335
155X-RAY DIFFRACTION155(chain V and resid 336:431)V336 - 431
156X-RAY DIFFRACTION156(chain V and resid 432:466)V432 - 466
157X-RAY DIFFRACTION157(chain V and resid 467:508)V467 - 508
158X-RAY DIFFRACTION158(chain V and resid 509:526)V509 - 526
159X-RAY DIFFRACTION159(chain W and resid 9:27)W9 - 27
160X-RAY DIFFRACTION160(chain W and resid 28:63)W28 - 63
161X-RAY DIFFRACTION161(chain W and resid 64:96)W64 - 96
162X-RAY DIFFRACTION162(chain W and resid 97:150)W97 - 150
163X-RAY DIFFRACTION163(chain W and resid 151:177)W151 - 177
164X-RAY DIFFRACTION164(chain W and resid 178:214)W178 - 214
165X-RAY DIFFRACTION165(chain W and resid 215:222)W215 - 222
166X-RAY DIFFRACTION166(chain W and resid 223:234)W223 - 234
167X-RAY DIFFRACTION167(chain X and resid 301:335)X301 - 335
168X-RAY DIFFRACTION168(chain X and resid 336:356)X336 - 356
169X-RAY DIFFRACTION169(chain X and resid 357:457)X357 - 457
170X-RAY DIFFRACTION170(chain X and resid 458:499)X458 - 499
171X-RAY DIFFRACTION171(chain X and resid 500:524)X500 - 524
172X-RAY DIFFRACTION172(chain Y and resid 9:40)Y9 - 40
173X-RAY DIFFRACTION173(chain Y and resid 41:52)Y41 - 52
174X-RAY DIFFRACTION174(chain Y and resid 53:112)Y53 - 112
175X-RAY DIFFRACTION175(chain Y and resid 113:150)Y113 - 150
176X-RAY DIFFRACTION176(chain Y and resid 151:166)Y151 - 166
177X-RAY DIFFRACTION177(chain Y and resid 167:212)Y167 - 212
178X-RAY DIFFRACTION178(chain Y and resid 213:222)Y213 - 222
179X-RAY DIFFRACTION179(chain Y and resid 223:234)Y223 - 234
180X-RAY DIFFRACTION180(chain Z and resid 301:335)Z301 - 335
181X-RAY DIFFRACTION181(chain Z and resid 336:431)Z336 - 431
182X-RAY DIFFRACTION182(chain Z and resid 432:465)Z432 - 465
183X-RAY DIFFRACTION183(chain Z and resid 466:502)Z466 - 502
184X-RAY DIFFRACTION184(chain Z and resid 503:524)Z503 - 524

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月:コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか? / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例:em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

他の情報も見る