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- PDB-3hfa: Crystal Structure of Mycobacterium Tuberculosis Proteasome open-g... -

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Open data

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Basic information

Entry

Database: PDB / ID: 3hfa

Title

Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant

Components

Proteasome (Alpha subunit) PrcA
Proteasome (Beta subunit) PrcB

Keywords

HYDROLASE /

Mycobacterium tuberculosis / Proteasome Endopeptidase / open gate /

mutant /

Proteasome

Function / homology

Function and homology information

symbiont-mediated perturbation of host defenses /

cell wall /

proteasome endopeptidase complex / proteasome core complex, beta-subunit complex / proteasome core complex, alpha-subunit complex / threonine-type endopeptidase activity / proteolysis involved in protein catabolic process / peptidoglycan-based cell wall / proteasomal protein catabolic process / modification-dependent protein catabolic process ...
Similarity search - Function

Biological species

Mycobacterium tuberculosis (bacteria)

Method

X-RAY DIFFRACTION /

SYNCHROTRON /

MOLECULAR REPLACEMENT / Resolution: 2.504 Å

Authors

Li, D. / Li, H.

Citation

Journal: Nature / Year: 2009
Title: Inhibitors selective for mycobacterial versus human proteasomes.
Authors: Lin, G. / Li, D. / de Carvalho, L.P. / Deng, H. / Tao, H. / Vogt, G. / Wu, K. / Schneider, J. / Chidawanyika, T. / Warren, J.D. / Li, H. / Nathan, C.

History

Deposition	May 11, 2009	Deposition site: RCSB / Processing site: RCSB
Revision 1.0	Sep 15, 2009	Provider: repository / Type: Initial release
Revision 1.1	Jul 13, 2011	Group: Version format compliance
Revision 1.2	Jul 24, 2019	Group: Data collection / Refinement description / Category: software Item: _software.classification / _software.name / _software.version
Revision 1.3	Sep 6, 2023	Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
Revision 1.4	Nov 29, 2023	Group: Database references / Category: pdbx_database_related / Item: _pdbx_database_related.db_name

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Structure visualization

Structure viewer	Molecule: MolmilJmol/JSmol

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Downloads & links

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Download

PDBx/mmCIF format	3hfa.cif.gz	1.2 MB	Display	PDBx/mmCIF format
PDB format	pdb3hfa.ent.gz	996.2 KB	Display	PDB format
PDBx/mmJSON format	3hfa.json.gz		Tree view	PDBx/mmJSON format
Others	Other downloads

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Validation report

Arichive directory	https://data.pdbj.org/pub/pdb/validation_reports/hf/3hfa ftp://data.pdbj.org/pub/pdb/validation_reports/hf/3hfa	HTTPS FTP

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Related structure data

Related structure data	3h6fC 3h6iC 3hf9C 2fhgS 2fhh C: citing same article (ref.) S: Starting model for refinement
Similar structure data	5trr-d 6ocz-d 3mi0-d 2fhh-d 3krd-d 6ode-d 3h6f-d 5trs-d 6ocw-d 3hf9-1 5ts0-d 3h6i-d 3mfe-d 5try-d 3hf9-2 Search similar-shape structures by Omokage search (details) Similarity search - Function & homologyF&H Search Similarity search - FunctionF&H Search Similarity search - HomologyF&H Search

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Links

PDB pages	PDBj / wwPDB / NCBI
Related items in Molecule of the Month	#166 - Oct 2013 Proteasome similarity (9) #80 - Aug 2006 AAA+ Proteases similarity (5) #60 - Dec 2004 Ubiquitin similarity (8) #176 - Aug 2014 Dynein similarity (5)

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Assembly

Deposited unit

H: Proteasome (Beta subunit) PrcB

C: Proteasome (Beta subunit) PrcB

E: Proteasome (Beta subunit) PrcB

G: Proteasome (Beta subunit) PrcB

J: Proteasome (Beta subunit) PrcB

L: Proteasome (Beta subunit) PrcB

N: Proteasome (Beta subunit) PrcB

P: Proteasome (Beta subunit) PrcB

R: Proteasome (Beta subunit) PrcB

T: Proteasome (Beta subunit) PrcB

V: Proteasome (Beta subunit) PrcB

X: Proteasome (Beta subunit) PrcB

Z: Proteasome (Beta subunit) PrcB

2: Proteasome (Beta subunit) PrcB

D: Proteasome (Alpha subunit) PrcA

A: Proteasome (Alpha subunit) PrcA

B: Proteasome (Alpha subunit) PrcA

F: Proteasome (Alpha subunit) PrcA

I: Proteasome (Alpha subunit) PrcA

K: Proteasome (Alpha subunit) PrcA

M: Proteasome (Alpha subunit) PrcA

O: Proteasome (Alpha subunit) PrcA

Q: Proteasome (Alpha subunit) PrcA

S: Proteasome (Alpha subunit) PrcA

U: Proteasome (Alpha subunit) PrcA

W: Proteasome (Alpha subunit) PrcA

Y: Proteasome (Alpha subunit) PrcA

1: Proteasome (Alpha subunit) PrcA

hetero molecules

722 kDa, 28 polymers
Search similar-shape structures of this assembly by Omokage search (details)

Idetical with deposited unit
defined by author

Unit cell

Length a, b, c (Å)	119.158, 221.437, 137.120
Angle α, β, γ (deg.)	90.00, 104.89, 90.00
Int Tables number	4
Space group name H-M	P12₁1

Noncrystallographic symmetry (NCS)

NCS domain:
NCS domain segments:

Dom-ID	Component-ID	Ens-ID	Beg auth comp-ID	Beg label comp-ID	End auth comp-ID	End label comp-ID	Selection details	Auth asym-ID	Label asym-ID	Auth seq-ID	Label seq-ID
1	1	1	THR	THR	SER	SER	chain H and (resseq 301:522 )	H	A	301 - 522	1 - 222
2	1	1	THR	THR	SER	SER	chain C and (resseq 301:522 )	C	B	301 - 522	1 - 222
3	1	1	THR	THR	SER	SER	chain E and (resseq 301:522 )	E	C	301 - 522	1 - 222
4	1	1	THR	THR	SER	SER	chain G and (resseq 301:522 )	G	D	301 - 522	1 - 222
5	1	1	THR	THR	SER	SER	chain J and (resseq 301:522 )	J	E	301 - 522	1 - 222
6	1	1	THR	THR	SER	SER	chain L and (resseq 301:522 )	L	F	301 - 522	1 - 222
7	1	1	THR	THR	SER	SER	chain N and (resseq 301:522 )	N	G	301 - 522	1 - 222
8	1	1	THR	THR	SER	SER	chain P and (resseq 301:522 )	P	H	301 - 522	1 - 222
9	1	1	THR	THR	SER	SER	chain R and (resseq 301:522 )	R	I	301 - 522	1 - 222
10	1	1	THR	THR	SER	SER	chain T and (resseq 301:522 )	T	J	301 - 522	1 - 222
11	1	1	THR	THR	SER	SER	chain V and (resseq 301:522 )	V	K	301 - 522	1 - 222
12	1	1	THR	THR	SER	SER	chain X and (resseq 301:522 )	X	L	301 - 522	1 - 222
13	1	1	THR	THR	SER	SER	chain Z and (resseq 301:522 )	Z	M	301 - 522	1 - 222
14	1	1	THR	THR	SER	SER	chain 2 and (resseq 301:522 )	2	N	301 - 522	1 - 222
1	1	2	MET	MET	ALA	ALA	chain D and (resseq 9:190 or resseq 204:230 )	D	O	9 - 190	1 - 182
1	2	2	GLY	GLY	LEU	LEU	chain D and (resseq 9:190 or resseq 204:230 )	D	O	204 - 230	196 - 222
2	1	2	MET	MET	ALA	ALA	chain A and (resseq 9:190 or resseq 204:230 )	A	P	9 - 190	1 - 182
2	2	2	GLY	GLY	LEU	LEU	chain A and (resseq 9:190 or resseq 204:230 )	A	P	204 - 230	196 - 222
3	1	2	MET	MET	ALA	ALA	chain F and (resseq 9:190 or resseq 204:230 )	F	R	9 - 190	1 - 182
3	2	2	GLY	GLY	LEU	LEU	chain F and (resseq 9:190 or resseq 204:230 )	F	R	204 - 230	196 - 222
4	1	2	MET	MET	ALA	ALA	chain I and (resseq 9:190 or resseq 204:230 )	I	S	9 - 190	1 - 182
4	2	2	GLY	GLY	LEU	LEU	chain I and (resseq 9:190 or resseq 204:230 )	I	S	204 - 230	196 - 222
5	1	2	MET	MET	ALA	ALA	chain K and (resseq 9:190 or resseq 204:230 )	K	T	9 - 190	1 - 182
5	2	2	GLY	GLY	LEU	LEU	chain K and (resseq 9:190 or resseq 204:230 )	K	T	204 - 230	196 - 222
6	1	2	MET	MET	ALA	ALA	chain M and (resseq 9:190 or resseq 204:230 )	M	U	9 - 190	1 - 182
6	2	2	GLY	GLY	LEU	LEU	chain M and (resseq 9:190 or resseq 204:230 )	M	U	204 - 230	196 - 222
7	1	2	MET	MET	ALA	ALA	chain O and (resseq 9:190 or resseq 204:230 )	O	V	9 - 190	1 - 182
7	2	2	GLY	GLY	LEU	LEU	chain O and (resseq 9:190 or resseq 204:230 )	O	V	204 - 230	196 - 222
8	1	2	MET	MET	ALA	ALA	chain Q and (resseq 9:190 or resseq 204:230 )	Q	W	9 - 190	1 - 182
8	2	2	GLY	GLY	LEU	LEU	chain Q and (resseq 9:190 or resseq 204:230 )	Q	W	204 - 230	196 - 222
9	1	2	MET	MET	ALA	ALA	chain S and (resseq 9:190 or resseq 204:230 )	S	X	9 - 190	1 - 182
9	2	2	GLY	GLY	LEU	LEU	chain S and (resseq 9:190 or resseq 204:230 )	S	X	204 - 230	196 - 222
10	1	2	MET	MET	ALA	ALA	chain U and (resseq 9:190 or resseq 204:230 )	U	Y	9 - 190	1 - 182
10	2	2	GLY	GLY	LEU	LEU	chain U and (resseq 9:190 or resseq 204:230 )	U	Y	204 - 230	196 - 222
11	1	2	MET	MET	ALA	ALA	chain W and (resseq 9:190 or resseq 204:230 )	W	Z	9 - 190	1 - 182
11	2	2	GLY	GLY	LEU	LEU	chain W and (resseq 9:190 or resseq 204:230 )	W	Z	204 - 230	196 - 222
12	1	2	MET	MET	ALA	ALA	chain Y and (resseq 9:190 or resseq 204:230 )	Y	AA	9 - 190	1 - 182
12	2	2	GLY	GLY	LEU	LEU	chain Y and (resseq 9:190 or resseq 204:230 )	Y	AA	204 - 230	196 - 222
13	1	2	MET	MET	ALA	ALA	chain 1 and (resseq 9:190 or resseq 204:230 )	1	BA	9 - 190	1 - 182
13	2	2	GLY	GLY	LEU	LEU	chain 1 and (resseq 9:190 or resseq 204:230 )	1	BA	204 - 230	196 - 222

NCS ensembles :

ID
1
2

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Components

#1: Protein	Proteasome (Beta subunit) PrcB / Proteasome / beta subunit Mass: 25274.264 Da / Num. of mol.: 14 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Mycobacterium tuberculosis (bacteria) / Gene: MT2170, prcB, Rv2110c / Plasmid: pACYCDuet / Production host: Escherichia coli (E. coli) / Strain (production host): bl21(de3) References: UniProt: O33245, UniProt: P9WHU1*PLUS, proteasome endopeptidase complex
#2: Protein	Proteasome (Alpha subunit) PrcA Mass: 25971.975 Da / Num. of mol.: 14 Source method: isolated from a genetically manipulated source Details: prcA-prcB-His6 / Source: (gene. exp.) Mycobacterium tuberculosis (bacteria) / Gene: prcA, Rv2109c / Plasmid: pACYCDuet / Production host: Escherichia coli (E. coli) / Strain (production host): bl21(de3) References: UniProt: O33244, UniProt: P9WHU1*PLUS, proteasome endopeptidase complex
#3: Chemical	... ChemComp-DMF / DIMETHYLFORMAMIDE / Dimethylformamide Mass: 73.094 Da / Num. of mol.: 58 / Source method: obtained synthetically / Formula: C₃H₇NO
#4: Water	ChemComp-HOH / water / Water Mass: 18.015 Da / Num. of mol.: 2109 / Source method: isolated from a natural source / Formula: H₂O

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Experimental details

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Experiment

Experiment	Method: X-RAY DIFFRACTION / Number of used crystals: 1

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Sample preparation

Crystal	Density Matthews: 2.44 Å³/Da / Density % sol: 49.52 %
Crystal grow	Temperature: 277 K / Method: vapor diffusion, sitting drop / pH: 5.8 Details: 13.5% PEG 6000, 60 mM sodium citrate, pH 5.8, 0.1M NaCl, VAPOR DIFFUSION, SITTING DROP, temperature 277K

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Data collection

Diffraction	Mean temperature: 100 K
Diffraction source	Source: SYNCHROTRON / Site: NSLS / Beamline: X29A / Wavelength: 1.0809 Å
Detector	Type: ADSC QUANTUM 315 / Detector: CCD / Date: Apr 2, 2008 / Details: mirrors
Radiation	Monochromator: Si 111 CHANNEL / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelength	Wavelength: 1.0809 Å / Relative weight: 1
Reflection	Resolution: 2.5→30 Å / Num. all: 235072 / Num. obs: 229825 / % possible obs: 97.8 % / Observed criterion σ(F): 2 / Observed criterion σ(I): 2 / Redundancy: 5.6 % / B_iso Wilson estimate: 46.69 Å² / R_merge(I) obs: 0.104 / Net I/σ(I): 9.8
Reflection shell	Resolution: 2.5→2.59 Å / R_merge(I) obs: 0.296 / Mean I/σ(I) obs: 1.92 / % possible all: 78.8

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Processing

Software

Name	Version	Classification
PHENIX	(phenix.refine)	refinement
CNS		refinement
CBASS		data collection
HKL-2000		data reduction
HKL-2000		data scaling
CNS		phasing

Refinement

Method to determine structure:

MOLECULAR REPLACEMENT
Starting model: PDB ENTRY 2FHG

2fhg

Resolution: 2.504→29.864 Å / Occupancy max: 1 / Occupancy min: 1 / SU ML: 2.59 / Cross valid method: THROUGHOUT / σ(F): 1 / Phase error: 20.71 / Stereochemistry target values: ML

	R_factor	Num. reflection	% reflection	Selection details
R_free	0.214	11454	4.98 %	RANDOM
R_work	0.173	218332	-	-
obs	0.175	229786	97.77 %	-

Solvent computation

Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL / B_sol: 47.955 Å² / k_sol: 0.337 e/Å³

Displacement parameters

B_iso max: 196.58 Å² / B_iso mean: 47.737 Å² / B_iso min: 6 Å²

	B_aniso -1	B_aniso -2	B_aniso -3
1-	-1.631 Å²	-0 Å²	-0.501 Å²
2-	-	-2.39 Å²	0 Å²
3-	-	-	3.317 Å²

Refinement step

Cycle: LAST / Resolution: 2.504→29.864 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	46124	0	290	2109	48523

Refine LS restraints

Refine-ID	Type	Dev ideal	Number
X-RAY DIFFRACTION	f_bond_d	0.006	47045
X-RAY DIFFRACTION	f_angle_d	0.988	63603
X-RAY DIFFRACTION	f_chiral_restr	0.094	7213
X-RAY DIFFRACTION	f_plane_restr	0.003	8424
X-RAY DIFFRACTION	f_dihedral_angle_d	16.145	16891

Refine LS restraints NCS

Ens-ID	Dom-ID	Auth asym-ID	Number	Refine-ID	Type	Rms dev position (Å)
1	1	H	1638	X-RAY DIFFRACTION	POSITIONAL	0.054
1	2	C	1638	X-RAY DIFFRACTION	POSITIONAL	0.054
1	3	E	1638	X-RAY DIFFRACTION	POSITIONAL	0.056
1	4	G	1638	X-RAY DIFFRACTION	POSITIONAL	0.055
1	5	J	1638	X-RAY DIFFRACTION	POSITIONAL	0.052
1	6	L	1638	X-RAY DIFFRACTION	POSITIONAL	0.052
1	7	N	1638	X-RAY DIFFRACTION	POSITIONAL	0.058
1	8	P	1638	X-RAY DIFFRACTION	POSITIONAL	0.05
1	9	R	1638	X-RAY DIFFRACTION	POSITIONAL	0.051
1	10	T	1638	X-RAY DIFFRACTION	POSITIONAL	0.057
1	11	V	1638	X-RAY DIFFRACTION	POSITIONAL	0.056
1	12	X	1638	X-RAY DIFFRACTION	POSITIONAL	0.05
1	13	Z	1638	X-RAY DIFFRACTION	POSITIONAL	0.049
1	14	2	1638	X-RAY DIFFRACTION	POSITIONAL	0.052
2	1	D	1614	X-RAY DIFFRACTION	POSITIONAL	0.049
2	2	A	1614	X-RAY DIFFRACTION	POSITIONAL	0.049
2	3	F	1614	X-RAY DIFFRACTION	POSITIONAL	0.043
2	4	I	1614	X-RAY DIFFRACTION	POSITIONAL	0.065
2	5	K	1614	X-RAY DIFFRACTION	POSITIONAL	0.037
2	6	M	1614	X-RAY DIFFRACTION	POSITIONAL	0.046
2	7	O	1607	X-RAY DIFFRACTION	POSITIONAL	0.06
2	8	Q	1614	X-RAY DIFFRACTION	POSITIONAL	0.042
2	9	S	1614	X-RAY DIFFRACTION	POSITIONAL	0.056
2	10	U	1614	X-RAY DIFFRACTION	POSITIONAL	0.056
2	11	W	1614	X-RAY DIFFRACTION	POSITIONAL	0.058
2	12	Y	1614	X-RAY DIFFRACTION	POSITIONAL	0.049
2	13	1	1614	X-RAY DIFFRACTION	POSITIONAL	0.042

LS refinement shell

Refine-ID: X-RAY DIFFRACTION / Total num. of bins used: 30

Resolution (Å)	R_factor R_free	Num. reflection R_free	R_factor R_work	Num. reflection R_work	Num. reflection all	% reflection obs (%)
2.504-2.533	0.342	303	0.272	5489	5792	74
2.533-2.562	0.306	322	0.256	6613	6935	89
2.562-2.594	0.319	365	0.247	6977	7342	93
2.594-2.626	0.283	377	0.235	7032	7409	95
2.626-2.661	0.293	395	0.227	7195	7590	97
2.661-2.697	0.274	385	0.222	7268	7653	98
2.697-2.736	0.285	365	0.213	7224	7589	97
2.736-2.777	0.266	386	0.21	7280	7666	98
2.777-2.82	0.274	404	0.199	7316	7720	99
2.82-2.866	0.255	430	0.19	7317	7747	99
2.866-2.916	0.26	387	0.191	7377	7764	99
2.916-2.969	0.25	355	0.191	7368	7723	99
2.969-3.026	0.256	377	0.189	7363	7740	99
3.026-3.087	0.233	369	0.183	7427	7796	100
3.087-3.154	0.231	419	0.181	7406	7825	100
3.154-3.228	0.232	378	0.178	7434	7812	100
3.228-3.308	0.226	370	0.174	7417	7787	100
3.308-3.398	0.221	374	0.173	7441	7815	100
3.398-3.497	0.203	350	0.156	7449	7799	100
3.497-3.61	0.198	388	0.153	7434	7822	100
3.61-3.739	0.2	387	0.162	7401	7788	100
3.739-3.888	0.193	382	0.15	7413	7795	100
3.888-4.065	0.177	408	0.143	7447	7855	100
4.065-4.279	0.163	384	0.14	7449	7833	100
4.279-4.546	0.168	374	0.132	7437	7811	100
4.546-4.895	0.158	398	0.13	7461	7859	100
4.895-5.385	0.165	436	0.142	7420	7856	100
5.385-6.159	0.197	380	0.154	7480	7860	100
6.159-7.737	0.169	423	0.146	7436	7859	100
7.737-29.866	0.15	383	0.15	7561	7944	100

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°²)	L12 (°²)	L13 (°²)	L22 (°²)	L23 (°²)	L33 (°²)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å²)	T12 (Å²)	T13 (Å²)	T22 (Å²)	T23 (Å²)	T33 (Å²)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	-0.0676	-0.0274	0.0231	0.016	-0.0158	-0.0393	0.5795	0.8333	0.0652	-0.3249	-0.2198	0.4226	-0.1076	-0.2817	0.0135	0.4201	0.0584	-0.107	0.8337	0.1715	0.3536	14.852	54.8913	-17.9442
2	0.1734	-0.0484	-0.1316	0.4418	0.1389	0.0208	0.2287	0.2675	0.8353	0.2989	-0.0135	-0.5874	-0.305	-0.0644	-0.0651	0.2949	-0.0192	0.0961	0.3608	0.1893	0.3299	40.201	54.3839	-13.6902
3	0.2762	0.3518	-0.48	0.1809	-0.131	0.7802	-0.0136	-0.3027	0.5506	0.3028	0.2592	-0.3394	0.08	-0.1465	1.0512	0.1987	-0.1157	0.0507	0.1967	0.2478	-0.235	34.7127	47.0124	-3.7147
4	0.1601	-0.1862	-0.226	0.4738	0.4695	0.2559	-0.0604	0.086	-0.1342	0.3846	0.0756	-0.2591	0.6084	0.0169	0.0337	0.2719	-0.141	0.0336	0.2283	0.0309	0.1634	37.3436	29.4981	-6.6782
5	1.5795	0.5334	-0.2467	0.3471	0.4793	0.6151	-0.1196	0.6529	-0.124	-0.206	0.0624	0.0281	0.1047	-0.3694	-0.1658	0.208	-0.1091	0.0072	0.4516	0.1157	0.0246	31.3233	42.9617	-14.3092
6	0.3534	0.137	0.0428	0.0494	-0.0902	0.1017	-0.0524	0.1722	0.6003	-0.8002	0.3297	0.0011	-0.1236	-0.9053	0.0035	0.5906	0.1193	0.1848	0.6708	0.3926	0.4448	37.1442	55.3992	-22.1169
7	0.2704	-0.1121	0.0611	0.2381	0.0139	0.0983	0.0512	0.4058	0.4888	-0.088	-0.1739	-0.6773	0	0.1951	0.0294	0.3392	-0.0779	0.0694	0.5308	0.2933	0.3886	47.9793	57.049	-19.5239
8	0.2156	0.0546	-0.4286	0.1563	-0.03	0.1417	0.0205	-0.2416	0.0499	0.2734	0.2664	-0.3253	0.0112	-0.1439	-0.0505	0.2588	-0.109	0.0142	0.2347	0.0659	0.2888	49.78	49.9646	-6.4347
9	0.4967	-0.5365	-0.3507	0.3799	-0.1277	0.3717	-0.038	0.1334	-0.0465	-0.2463	-0.0436	0.1268	-0.2029	0.0357	-0.0103	0.2857	-0.0919	-0.0508	0.1938	0.0458	0.1073	50.6825	21.7722	13.5657
10	0.0607	-0.0993	-0.3384	0.9599	-0.2264	0.4155	-0.0754	0.0424	-0.0152	-0.0309	0.0042	-0.23	-0.2675	-0.163	-0.2119	0.328	-0.0581	-0.065	0.1466	0.0776	0.051	39.5872	36.7283	11.1933
11	0.2406	-0.3605	-0.1845	0.4299	0.3012	1.0331	-0.2012	-0.0201	-0.0053	-0.2531	0.1703	-0.0186	-0.3007	0.1655	0.0143	0.2325	-0.1492	-0.0268	0.198	0.0348	0.1018	51.1401	29.6097	23.0631
12	0.6437	0.5062	-0.7247	0.8068	0.3868	0.1504	-0.0089	0.1566	-0.1666	-0.1141	0.0976	-0.3682	-0.0944	0.4241	0.7372	0.1688	-0.1381	0.0631	0.2799	0.0366	0.0872	60.4367	19.631	15.5864
13	-0.0291	-0.1095	-0.0422	0.1576	0.1082	0.0202	-0.1918	0.1605	0.3259	-0.2446	-0.1019	-0.4144	-0.5736	0.5135	-0.0171	0.4136	-0.2637	0.0604	0.3446	0.0759	0.2123	67.746	19.7696	12.9846
14	0.3994	0.0161	0.3053	-0.1004	0.4191	0.5615	-0.3946	0.0238	-0.4668	-0.1785	-0.1976	0.5108	-1.4399	-0.4503	0.037	0.7022	0.112	-0.3068	0.5351	0.3759	1.064	-23.9755	55.8364	12.1957
15	-0.0405	-0.0234	0.1293	-0.0248	0.1093	-0.0465	-0.5913	0.0858	-0.2927	0.0179	0.2874	0.1505	-0.5314	-0.2397	0.0275	0.576	0.1732	-0.4706	0.9375	0.2867	1.4221	-34.9862	42.2607	16.4738
16	0.1383	0.3046	0.0166	-0.0237	-0.0183	0.1635	-0.0925	-0.2893	0.2724	-0.3121	0.079	-0.3694	0.1406	-0.3916	0.0046	0.2511	0.0373	-0.1951	0.497	0.3869	0.8785	-24.8844	43.6792	24.0025
17	0.0764	-0.1327	-0.2228	-0.0228	-0.0706	0.0953	0.3548	-0.1101	-0.6356	-0.2809	0.4085	0.7058	0.5746	-0.4653	-0.0166	0.3102	-0.1358	-0.3359	0.4021	0.4406	1.066	-19.7252	40.7893	16.9917
18	0.0642	-0.2072	-0.0012	-0.0695	-0.0725	0.0323	-0.18	-0.2011	0.181	-0.253	-0.0694	0.162	0.2448	-0.103	0.0867	0.1897	-0.0177	-0.2179	0.3549	0.106	0.8545	-12.9645	40.9714	33.4194
19	0.055	0.0278	-0.0208	0.1209	-0.0333	0.1402	0.3949	-0.1082	0.1504	-0.1624	0.0209	0.2573	-0.0236	0.2178	-0.0458	0.2989	-0.0745	-0.0269	0.3427	0.3016	0.6857	-12.943	49.5133	21.0232
20	0.8054	-0.0369	0.3694	0.5684	0.5466	0.1549	0.1483	0.0934	-0.0239	-0.176	0.0854	0.2623	-1.0168	-0.6045	-0.0015	0.4832	0.0721	-0.0675	0.4291	0.2965	0.9383	-20.1935	52.2536	22.8749
21	0.3694	0.3535	-0.1154	0.3263	0.7607	1.0253	0.0251	-0.0021	0.2711	-0.3061	0.0981	0.1329	-0.2916	-1.315	-0.1012	0.3561	0.3246	-0.1892	0.9677	0.418	1.2093	-36.9611	50.9135	25.9996
22	0.5075	-0.5255	-0.0212	0.1432	-0.5837	1.1351	-0.0559	0.1376	-0.0527	-0.2215	0.9317	0.2602	0.1127	-1.6428	-0.2816	0.2953	-0.3409	-0.1832	1.3519	0.6908	0.6232	-28.0495	33.7673	-8.1761
23	-0.0736	-0.0484	-0.0218	-0.0519	0.1986	0.0464	0.0172	-0.2663	-0.1524	-0.3739	0.4176	0.5558	0.3897	-0.6019	0.0182	0.2413	-0.3995	-0.2899	1.1883	0.6762	0.7746	-28.0271	22.4986	3.607
24	0.3582	-0.0447	-0.1497	0.1471	-0.1529	-0.128	-0.0386	-0.268	-0.1287	-0.2528	0.4869	0.1858	0.6255	-0.7174	-0.0671	0.269	-0.2089	-0.1401	0.6697	0.3815	0.3807	-18.9065	25.67	-0.9369
25	-0.0067	0.0756	-0.0771	0.1272	0.1051	-0.0407	-0	-0.5856	0.2336	-0.1919	0.0069	-0.2352	-0.1355	-0.5279	0.0176	0.3564	-0.2086	-0.2335	1.0484	0.4255	0.5331	-22.5364	21.5973	16.52
26	0.0172	-0.2472	-0.2833	0.173	0.1464	0.3052	-0.224	0.0683	0.3143	-0.2753	0.8608	0.1679	0.0297	-1.2993	-0.3754	0.1542	-0.1543	-0.109	0.8898	0.3026	0.4343	-21.6891	34.9157	1.94
27	0.1268	0.0451	0.0069	0.3116	0.0669	0.1805	0.4854	-0.0729	0.1983	-0.0298	-0.4598	0.1538	0.5904	-0.4372	0.0305	0.4269	-0.3214	-0.1345	1.6196	0.6718	0.6809	-37.629	26.3837	10.963
28	0.0752	-0.1668	0.1437	0.1947	0.0855	-0.0505	-0.6582	-0.1958	0.0713	-0.4315	0.7982	0.2062	-0.5228	-1.2078	0.0102	0.1801	-0.0536	-0.1295	1.6159	0.7809	0.7162	-38.8856	35.2662	-2.2373
29	-0.0271	-0.0172	-0.0217	0.0677	0.0893	0.0597	0.4419	-0.1101	-0.0982	-0.3778	-0.3284	0.5772	-0.0492	-0.1405	-0.0286	0.6091	-0.6296	-0.6522	1.6792	0.9145	1.2669	-45.0961	26.4976	-9.6184
30	0.8913	-0.4448	-0.0106	0.7846	0.2236	0.0224	-0.1727	-0.3762	-0.2386	0.1712	-0.0885	-0.5222	0.2983	0.0664	0.0574	0.6377	-0.8517	-0.4029	1.5195	0.8951	0.623	-35.6278	19.8321	-13.1867
31	-0.1501	0.1294	0.0381	0.1229	0.0441	0.0485	-0.0861	-0.5074	-0.8593	-0.208	0.4283	0.6098	0.2969	0.191	0.0323	0.7281	-0.7806	-0.5322	1.5143	0.8176	0.8795	-37.315	14.9387	-1.0698
32	-0.1968	0.9907	0.2498	0.6872	-0.2643	0.5153	-0.2537	0.313	0.4141	-0.1634	0.5641	0.7743	-0.0836	-0.0527	-0.0781	0.1938	-0.1348	-0.2083	0.4819	0.3663	0.5684	-17.6919	-2.1587	20.3501
33	0.5923	-0.7176	-0.4632	0.2746	0.2916	0.5244	0.1094	-0.014	0.029	-0.4016	0.0974	0.207	-0.0008	0.0402	0.0679	0.409	-0.3433	-0.341	0.5577	0.3936	0.4052	-13.6294	3.5854	6.8365
34	0.0224	-0.1016	-0.0312	0.226	-0.1313	-0.098	-0.4623	0.2502	0.1491	-0.4983	0.4432	0.2136	0.0188	0.0348	0.0259	0.3603	-0.2721	-0.2585	0.5588	0.2197	0.3929	-8.6961	-8.7121	11.4025
35	0.4845	0.5653	0.8597	0.3855	0.3491	0.4201	-0.1867	0.1592	0.1493	-0.0395	0.7656	0.8929	-0.5788	-0.9665	1.1299	-0.2196	-0.364	-0.2701	0.4409	0.3312	0.5022	-23.554	-12.8363	19.9265
36	0.0361	-0.021	0.1074	0.1147	-0.0186	0.1332	-0.0172	0.3865	0.136	-0.3248	0.421	0.3134	0.0951	0.4226	0.013	0.1302	-0.1595	-0.2059	0.444	0.1388	0.4698	-28.2273	-20.9839	27.8541
37	0.4668	0.1382	0.025	-0.4476	0.272	0.2425	0.0744	-0.9176	-1.1466	0.1207	0.0905	-0.0095	0.3186	-0.2833	0.0726	0.3174	-0.002	0.0952	0.2981	0.1711	0.4497	13.1242	-55.1748	76.6806
38	0.0264	-0.0098	-0.0475	0.0747	-0.0456	0.036	-0.5232	-0.4319	-0.3252	0.0643	0.0097	0.0649	0.3887	0.1018	0.031	0.3327	-0.0064	0.0696	0.534	0.0388	0.2494	1.6017	-43.6247	83.024
39	0.3808	-0.2159	0.0192	-0.0486	-0.0004	0.0782	-0.0852	-0.0608	0.2032	-0.1439	0.0287	-0.0259	-0.0313	-0.2029	0.0088	0.2385	0.04	0.0555	0.1513	-0.0098	0.2144	6.9703	-41.7772	69.3578
40	0.3804	-0.0139	0.0728	-0.0143	0.0272	0.2915	-0.4104	0.6575	-0.5417	-0.6176	0.2741	-0.029	0.4057	-0.3497	0.0533	0.3152	-0.0706	0.1285	0.2004	-0.0561	0.1693	3.759	-41.3281	54.0741
41	0.5699	0.0322	-0.4273	0.3968	-0.5229	0.7182	-0.2605	0.0268	-0.7144	-0.2445	0.1512	-0.1721	0.3268	-0.0626	0.1143	0.2618	-0.0369	0.1219	0.1154	-0.0133	0.2957	9.6172	-51.2365	66.0445
42	0.0078	0.0935	-0.1259	0.173	-0.2373	0.1602	-0.0244	-0.5444	-0.878	0.1949	-0.0353	0.1753	0.8493	-0.4981	0.0379	0.6257	-0.1728	0.1344	0.3945	0.1827	0.7439	-3.4136	-60.1673	77.5664
43	0.0897	0.0864	0.0798	0.1621	0.0564	0.0503	-0.62	-0.1876	0.217	0.0103	0.2275	0.3478	-0.0953	0.4751	0.0418	0.2906	0.0258	0.0238	0.4571	0.0949	0.3356	-7.5472	-45.2379	71.2099
44	0.0405	0.0597	0.1024	0.0743	0.0019	0.0259	-0.4979	-0.7407	-0.073	-0.0499	0.5456	0.0593	-0.2875	-0.3971	-0.0242	0.324	0.2355	0.1184	0.6471	0.0158	0.2992	-10.1476	-44.4709	77.1223
45	0.202	-0.285	0.3054	-0.0263	-0.6477	0.7593	0.0669	0.1133	-0.037	0.0102	0.2112	0.3493	0.2986	0.0203	-0.1779	0.1564	-0.0007	-0.0596	0.1266	0.0477	0.2915	-8.7726	-20.2797	50.1843
46	-0.0171	-0.2393	0.3682	0.2541	0.1697	0.1154	-0.0931	0.1134	-0.0907	0.1763	0.1474	-0.0761	0.067	0.1747	-0.0377	0.1897	0.0535	0.0119	0.1619	-0.0217	0.155	1.8061	-24.8936	65.3467
47	-0.0584	0.2879	0.0281	0.7925	-0.2539	0.7974	0.0106	0.0522	0.2123	0.1525	0.1252	0.2623	-0.0877	0.066	-0.0528	0.1254	-0.0036	0.0642	0.1285	0.0364	0.2115	-6.656	-12.359	59.3788
48	0.8671	0.062	-0.5906	1.1287	0.2293	0.2674	0.0642	0.0787	-0.013	-0.118	0.1045	0.5685	0.0143	-0.2566	-0.0356	0.0527	-0.0433	-0.0304	0.143	0.1183	0.4084	-20.5532	-15.9834	51.2357
49	0.1225	0.1073	-0.0346	0.3002	0.2434	1.1896	0.1115	-0.0965	0.1399	0.3025	-0.2092	0.1586	-0.0237	-0.4071	-0.1409	0.1524	-0.1666	-0.0174	0.28	0.2463	0.5007	-27.17	-19.4433	47.1986
50	0.01	-0.0526	0.0057	0.0673	0.0155	0.0466	0.3264	-0.2997	-0.3438	0.5666	-0.1289	-0.1669	0.1861	0.036	0.0297	0.6919	0.141	0.0245	0.4322	0.1499	0.3688	54.0005	-38.2349	85.1507
51	-0.0244	0.1868	0.0222	0.9529	0.5262	0.2542	-0.1808	-0.0367	0.1396	0.0119	0.132	-0.7937	0.0073	0.0422	0.0621	0.159	0.0729	-0.0493	0.1781	0.0078	0.3018	68.4734	-20.5525	72.9742
52	0.4867	-0.2203	0.2142	0.1057	-0.0261	0.5771	0.0655	-0.1215	0.1606	-0.185	0.0301	-0.2008	0.2844	-0.0713	-0.0941	0.1739	0.0694	-0.0161	0.3776	0.0349	0.1981	53.8231	-10.6931	72.8394
53	1.0517	-0.5365	-0.3399	0.0472	0.1394	0.88	-0.0075	-0.5354	0.0002	0.1972	-0.2392	-0.4805	0.111	0.0104	0.1091	0.2369	0.0466	-0.1001	0.3099	0.0003	0.2162	61.1702	-17.2119	80.0045
54	0.0812	-0.0844	0.0413	-0.0322	0.0141	-0.1459	-0.2963	-0.4345	0.3526	0.6468	-0.1404	-0.4877	0.7968	-0.4038	0.0583	0.6298	0.197	-0.3042	0.4854	-0.0189	0.6472	74.2741	-20.8377	87.8359
55	0.0038	0.0673	-0.1342	0.6896	-0.313	0.1953	-0.1354	-0.1122	0.4296	0.2392	-0.3195	-1.6205	-0.0173	0.5757	0.1523	0.1996	0.0951	-0.2204	0.4413	0.1594	0.8309	81.2236	-14.9904	80.0366
56	0.0463	0.0552	0.0141	-0.0183	-0.0419	0.0515	-0.5055	0.2782	0.2572	-0.432	-0.224	-0.2929	-0.0704	0.3215	0.0713	0.2464	0.0133	-0.0963	0.3132	-0.0646	0.489	70.1798	-2.8414	70.2834
57	0.0762	-0.0318	0.1044	-0.0531	-0.0854	0.2018	-0.6297	0.4263	0.0186	-0.6479	-0.1215	-0.8914	1.2874	0.2117	0.0311	0.2602	0.1859	0.1955	0.8804	0.3524	1.0906	83.0692	-11.9499	69.5718
58	-0.0705	-0.0325	-0.0676	0.7345	-0.1441	-0.1456	-0.355	0.0937	-0.0942	0.2896	0.1107	0.0679	0.012	0.0321	0.0457	0.1296	0.0206	-0.012	0.1729	0.0059	0.174	56.3759	13.7363	49.5534
59	-0.0331	-0.0133	-0.2303	0.2751	-0.1903	0.2307	0.0575	0.0313	0.1018	0.0173	-0.0803	0.086	0.0284	0.039	-0.0097	0.1623	0.0554	0.0068	0.1862	0.0342	0.1158	58.9303	-4.7054	53.6615
60	0.0374	-0.6859	-0.1469	0.8346	0.4732	0.2809	0.0196	0.1404	-0.0896	-0.1186	0.0258	0.0724	0.1736	0.0055	-0.0227	0.0433	0.0172	-0.0131	0.1971	-0.0044	0.1733	59.6152	-1.4064	43.0427
61	-0.0351	0.3435	-0.667	0.8867	0.3293	0.002	0.02	-0.0139	0.0473	0.1098	0.0188	-0.0675	-0.1193	-0.0475	0.0172	0.1263	-0.0288	-0.0554	0.24	0.0035	0.1769	63.3476	16.3604	44.0574
62	0.3753	-0.7059	0.1887	0.5781	0.1411	0.1123	0.2401	0.0435	0.3583	0.0801	-0.023	-0.9327	-0.4845	0.3022	0.5219	-0.0824	-0.0424	-0.272	0.2818	-0.0934	0.187	67.2225	24.2293	50.0922
63	0.1826	0.0403	0.6287	0.199	0.0299	0.2998	-0.3872	0.4237	0.7232	-0.057	0.0925	0.2839	-0.3329	0.3184	-0.0042	0.0831	-0.0344	-0.0849	0.1703	0.1075	0.4542	-15.5298	16.8259	48.3256
64	0.338	0.4207	-0.138	0.0636	0.0929	0.2556	-0.3754	0.2061	0.6468	-0.2988	0.1619	0.4223	-0.0512	0.1132	0.0563	0.2241	-0.1092	-0.2904	0.2476	0.2815	0.7035	-18.864	24.5366	31.1581
65	0.4114	0.226	0.3773	0.8351	0.5343	1.0935	-0.1762	0.1265	0.1781	-0.1655	0.2054	0.5298	-0.0011	0.2027	-0.16	0.0588	-0.0875	-0.1146	0.2568	0.1899	0.4641	-18.4965	13.1198	32.3227
66	0.5121	0.0788	-0.0792	0.2302	0.653	0.0236	-0.0689	-0.0715	0.1196	0.1126	0.0028	0.2718	-0.0736	-0.0348	-0.1354	0.0482	0.0434	0.0371	0.1228	0.1009	0.448	-22.3139	11.0511	50.2888
67	0.1161	-0.1809	0.125	0.2594	0.1608	1.0935	-0.3311	-0.0616	0.3351	0.3089	0.1201	0.1968	-0.0373	-0.6419	-0.129	0.0329	0.1226	0.0301	0.2213	0.055	0.6404	-26.3196	15.1365	59.0289
68	-0.0727	0.0334	-0.1087	0.3216	0.1165	0.1794	-0.124	-0.2718	-0.1546	-1.0087	0.7464	0.3555	-0.0783	0.2314	-0.0535	0.4255	-0.1635	-0.1237	0.3703	0.1504	0.1849	-10.567	39.6421	-22.5386
69	1.467	-1.3762	-0.5698	1.4168	0.7177	1.3085	0.6571	-0.7797	0.085	-1.3005	0.1197	-0.2331	0.1302	-0.0605	0.1512	0.7532	-0.3008	-0.3832	0.1817	0.2014	0.2573	-6.9228	15.2379	-30.1128
70	0.2751	0.1584	-0.2551	0.9786	0.1982	0.5756	0.0204	-0.2985	-0.2488	-0.4501	0.4782	0.0853	0.5454	-0.4277	0.3679	0.3573	-0.3442	-0.2978	0.4882	0.3184	0.2719	-5.3057	14.4231	-13.5884
71	0.465	-0.39	-0.0211	0.3267	-0.138	0.1947	0.0108	-0.3738	-0.0537	-0.3147	0.2624	0.1908	0.2217	-0.202	-0.0458	0.3088	-0.3016	-0.1902	0.4634	0.2435	0.1997	-9.6141	25.7825	-14.8443
72	0.2931	-0.221	0.125	0.0048	0.0434	0.2148	0.3675	-0.0293	-0.4291	0.2968	-0.1928	-0.3657	0.3757	-0.4783	-0.0641	0.5189	-0.4159	-0.3927	0.5131	0.3346	0.5628	-18.0238	14.6027	-18.7583
73	0.8164	-1.5714	-0.6989	1.9168	1.2755	1.5977	0.6034	0.0527	-0.2064	-1.0727	0.0648	-0.4191	-0.2259	-0.5001	0.2484	0.8521	-0.27	-0.5144	0.4441	0.2729	0.324	-19.8712	20.2555	-33.1517
74	-0.0554	-0.084	0.1977	0.561	-0.0353	0.3412	0.7781	-0.1042	-0.7549	-1.4814	-0.0027	0.4443	0.0323	-0.4791	-0.0959	1.4566	-0.1136	-0.59	0.1935	0.0758	0.4839	-12.7717	11.9352	-37.4498
75	1.2392	-0.1646	-0.9593	0.1925	-0.1592	0.3207	0.7964	-0.7878	-1.2032	-1.1676	-0.365	-0.1915	0.2671	0.6657	-0.0643	1.0406	-0.2456	-0.4798	0.224	0.19	0.6887	-6.7011	4.0473	-28.6265
76	-0.0845	0.3875	-0.0854	0.4497	-0.2895	0.0573	-0.0222	0.0497	0.2261	-0.2834	0.2443	0.3874	0.3973	-0.2303	-0.0086	0.4503	-0.227	-0.1793	0.2667	0.1134	0.191	4.8749	-11.5679	-1.8905
77	-0.0562	-0.1404	0.0164	0.2939	-0.0819	0.0917	-0.0416	0.0426	0.1708	-0.3207	0.018	0.1017	0.1858	-0.1227	-0.0034	0.3353	-0.2485	-0.2203	0.3232	0.1756	0.201	7.9211	5.106	-9.0597
78	0.4717	0.4766	-0.0395	-0.0003	-0.6411	0.0138	-0.2378	0.176	0.0459	-0.4801	0.1016	0.0765	-0.1618	0.4902	-0.0098	0.5553	-0.2071	-0.1159	0.4177	0.0532	0.2148	15.9326	-4.0991	-6.6573
79	0.3325	0.28	-0.5469	0.7862	0.2532	0.4255	-0.0989	-0.0352	-0.137	-0.4337	0.1279	0.1642	0.402	-0.1255	-0.4136	0.5091	-0.2777	-0.1996	0.2927	0.0269	0.1396	9.5242	-20.6887	-5.1163
80	0.0577	0.0682	-0.0651	-0.0412	-0.0727	0.0178	0.3881	0.6072	-0.4703	-0.2961	-0.0639	0.7529	0.6577	0.3347	-0.0598	0.9825	-0.5077	-0.3628	0.6593	-0.0096	0.4254	1.5844	-27.3047	-7.6242
81	0.7012	0.1967	-0.0375	0.0767	0.2625	-0.2967	-0.2617	-0.6694	-0.2025	0.5941	0.2708	-0.0633	0.2261	-0.1209	-0.0121	0.5026	0.0925	-0.0162	0.3604	0.0962	0.1604	20.4468	-32.6367	95.7423
82	0.1182	-0.0978	-0.1401	0.122	0.2112	-0.1513	-0.1051	-0.3642	0.2145	0.0458	0.0764	-0.2025	0.0177	-0.0029	-0.0159	0.2608	-0.0095	0.016	0.2471	0.0149	0.1308	17.2961	-23.5758	86.4795
83	0.2466	0.3283	0.1091	0.2473	-0.0012	0.1546	-0.0528	0.1476	0.0408	0.0792	-0.0496	-0.0756	0.0277	-0.0922	0.0118	0.2604	-0.0284	0.0359	0.2242	-0.0091	0.0687	14.235	-29.1742	78.6498
84	0.1162	0.3217	0.0021	0.6098	0.0761	0.0169	-0.2777	-0.0017	-0.568	0.3987	0.0838	0.4144	0.1597	-0.0189	-0.0108	0.3405	-0.065	0.1001	0.4183	-0.0076	0.1901	6.2513	-27.2791	88.9241
85	0.0782	0.2165	-0.33	0.2691	0.2189	0.1896	-0.2034	-0.1477	-0.4144	0.6703	-0.0114	0.0153	0.9269	-0.3508	0.0238	0.5701	-0.0787	0.1413	0.3347	0.1258	0.198	11.0747	-36.4935	95.5049
86	0.0564	0.0697	0.0516	-0.0733	-0.0642	0.0139	-0.2617	-0.123	-0.1449	0.6637	0.318	0.4845	0.1945	-0.0931	-0.0083	0.8771	0.0427	0.2415	0.6875	0.0784	0.2336	4.5326	-29.0369	106.8575
87	0.6079	-0.3834	0.5333	1.1328	0.119	0.3481	-0.2958	-0.0828	0.394	0.8919	0.2064	-0.1046	0.2285	-0.3497	-0.0463	0.538	0.107	0.0888	0.4234	0.0838	0.067	8.7862	-18.776	98.4877
88	0.4536	-0.2033	0.2728	0.366	-0.3757	0.2057	-0.0598	-0.2544	0.801	0.918	-0.1569	-0.6296	0.1179	-0.338	-0.115	0.7297	-0.0117	-0.0012	0.4241	-0.1269	0.1111	9.3546	-15.04	101.3525
89	0.1728	-0.5814	0.5049	0.3046	-0.0555	0.3487	0.1244	0.1975	-0.0836	0.2069	0.1433	0.4112	0.0106	0.0046	0.0317	0.1028	0.0413	0.0493	0.1649	0.057	0.2341	-0.5328	4.9202	69.471
90	0.384	-0.0257	0.0083	0.318	0.2136	-0.0206	0.0627	0.1008	-0.3166	0.0121	0.0859	-0.1039	0.4738	-0.2521	0.0002	0.1812	0.0253	0.0297	0.1606	0.0294	0.2103	7.5369	-2.6526	73.4156
91	0.6007	0.1755	0.4238	0.4752	0.0067	0.198	0.033	0.0338	0.0084	0.115	-0.0362	-0.0451	-0.085	0.0739	0.0082	0.1507	0.0074	0.0131	0.1546	0.0187	0.0793	15.9502	-0.1272	76.1294
92	0.4871	0.012	0.0753	0.5133	-0.3237	-0.0446	0.0487	0.0488	0.2013	0.2584	0.0498	0.4088	-0.0214	-0.0227	-0.0315	0.1437	0.047	0.1373	0.1787	0.0458	0.2256	-0.902	12.8791	74.1688
93	0.4698	0.7339	0.0773	0.6578	0.6584	-0.0223	-0.1554	-0.8079	0.77	-0.3318	0.1635	0.8066	-0.5549	-0.4492	-0.5361	-0.0022	-0.0609	0.4136	0.237	0.1294	0.1827	-10.9848	12.2567	77.5655
94	0.5812	-0.4258	0.2947	0.0296	0.7149	-0.044	-0.2753	-0.3399	-0.1549	0.6467	0.2246	-0.0099	0.1145	0.2186	0.0866	0.4698	0.0755	-0.0277	0.308	0.1147	0.2646	44.3207	-23.7657	96.626
95	0.1533	0.0887	-0.0011	0.2427	0.0592	0.0299	-0.0301	-0.0679	0.1496	-0.1912	-0.0792	-0.2359	-0.0726	0.0144	0.04	0.135	0.0004	-0.033	0.2314	0.0808	0.1356	45.8487	-12.1443	88.0782
96	0.5491	0.0836	0.4704	-0.1208	0.1148	0.3607	0.0272	0.0587	0.1179	-0.0834	-0.1739	0.0229	0.0495	-0.1285	0.0768	0.1293	-0.0045	0.0161	0.2308	0.0546	0.118	31.3516	-13.2754	84.2315
97	0.7243	0.6317	-0.0869	0.5432	-0.0939	0.0812	0.0311	0.0103	-0.0296	0.5751	-0.1317	-0.0321	0.0721	-0.3689	-0.0197	0.2674	0.0554	0.0139	0.2771	0.0685	0.1452	35.6256	-15.8677	94.2788
98	0.0375	-0.0319	0.0054	-0.0814	0.0253	0.033	0.0314	-0.624	-0.4154	0.1737	0.0547	-0.1847	0.2218	0.0964	0.0106	0.5477	0.084	-0.0861	0.4793	0.1447	0.2513	43.0589	-18.4514	106.4338
99	0.0964	0.0669	0.1216	0.3031	0.105	0.0656	-0.4755	-0.6801	0.0951	1.099	0.2033	-0.4329	-0.3111	-0.2098	0.0575	0.6376	-0.0336	-0.221	0.4906	0.0412	0.3559	46.3516	-8.3819	109.5827
100	-0.0203	-0.0648	0.003	-0.0822	0.104	-0.0665	-0.1757	-0.2655	0.5333	0.3952	0.0398	-0.567	-0.2547	-0.1947	-0.0144	0.3367	0.0592	-0.1583	0.3061	0.035	0.262	43.1273	-0.927	94.9629
101	-0.009	0.0724	-0.0659	-0.1223	-0.0044	0.0053	-0.252	0.6715	-0.1484	-0.1729	0.376	-0.7994	0.0343	0.212	-0.0301	0.2894	-0.1109	-0.2303	0.3171	0.063	0.589	52.4347	0.2364	100.06
102	0.4233	-0.3825	0.5266	0.742	-0.4621	-0.2452	0.1013	0.195	-0.422	0.2146	-0.0189	0.2173	-0.0436	0.0742	-0.0062	0.1894	-0.0067	0.0005	0.167	0.0252	0.1716	30.2179	19.4153	70.1318
103	0.1149	-0.0322	-0.1901	-0.0246	-0.0405	0.0943	0.0001	-0.2322	0.0099	0.2022	-0.1226	-0.1658	0.1654	-0.4175	-0.006	0.1671	0.0071	-0.0284	0.1824	0.0368	0.1525	35.183	9.0029	72.383
104	0.0344	0.2412	-0.5904	0.9654	-0.3116	0.5896	-0.0297	-0.0803	-0.0521	0.0852	-0.1751	-0.2025	-0.0622	0.1377	0.1485	0.1121	-0.012	-0.0458	0.1901	0.056	0.1333	42.6549	10.0765	67.8991
105	0.4045	0.3074	-0.2767	0.3402	0.4664	0.3538	0.0196	-0.0963	0.2046	0.3364	0.0102	0.0822	-0.2233	-0.0191	0.0142	0.2555	-0.0223	0.0043	0.1598	-0.0183	0.1013	34.8713	26.7751	73.4149
106	0.2744	0.0467	0.2116	0.1543	0.1334	-0.1277	-0.0764	-0.2965	0.3012	0.4765	0.1112	-0.0071	-0.0808	0.1876	-0.0627	0.4351	-0.0132	0.0174	0.2926	-0.0553	0.126	31.3827	32.5182	77.9018
107	0.0807	0.0519	0.0424	-0.0727	0.0524	0.0131	-0.1262	0.7997	0.2754	0.3347	-0.0217	0.0989	-1.2515	-0.1694	-0.0056	0.7719	-0.2195	-0.3912	0.6042	0.4652	0.8333	-0.8754	66.6597	4.4836
108	0.0333	-0.2322	-0.0083	0.5095	0.0401	0.3549	0.0248	-0.258	0.6253	-0.1383	-0.0522	0.4122	-0.1383	-0.6745	-0.1185	0.3781	0.0517	-0.1403	0.3837	0.1175	0.9621	-6.8829	68.4862	29.2858
109	0.3166	-0.2397	-0.0018	0.3229	-0.0026	0.1751	0.0171	-0.0052	0.2462	-0.3049	0.1402	0.1938	0.0169	-0.061	-0.1262	0.2056	-0.0219	-0.0651	0.1528	0.1477	0.4158	4.9302	56.2057	27.3379
110	0.4323	0.0689	0.1252	-0.3491	-0.1164	0.7169	0.2298	0.3428	0.1344	-0.086	0.5064	0.1241	-0.1876	0.109	-0.0861	0.3278	0.0042	-0.1891	0.2192	0.1086	0.4774	2.6149	61.7472	24.1051
111	0.308	0.4622	-0.1493	-0.0104	0.1105	1.3382	0.6758	0.1973	0.5934	-0.0883	0.4744	0.2045	-0.4968	0.2324	-0.0714	0.3025	-0.0578	-0.0587	0.2495	0.1541	0.6824	9.0938	68.5532	27.4182
112	-0.0702	-0.0799	-0.1725	0.0576	0.0049	0.3219	0.755	0.4279	0.4137	-0.2297	0.3561	0.2012	-0.2156	-0.868	-0.0822	0.6843	0.0022	-0.1655	0.263	0.1469	0.809	0.1253	76.0387	24.9584
113	-0.0401	-0.0255	-0.0171	0.121	-0.0065	-0.0178	-0.0472	-0.1457	0.8192	-0.4635	0.1679	0.3921	-0.542	-0.1721	-0.0063	0.6305	0.1139	-0.0297	0.3849	0.0643	1.0284	-1.4724	80.9709	34.5682
114	0.1107	0.1013	-0.31	0.1641	0.231	0.221	-0.239	-0.4489	0.0493	0.737	0.3482	0.6041	-0.3719	-0.5826	-0.088	0.2863	0.1712	0.0555	0.4287	0.0096	0.7157	-6.2333	68.0113	40.152
115	0.6479	-0.4181	0.651	0.3105	-0.6453	0.8637	-0.1157	0.3836	-0.0543	0.064	0.1048	0.1912	-0.1252	0.0556	-0.0721	0.0731	0.0191	0.0213	0.082	0.0531	0.2507	11.1379	35.7732	56.7565
116	0.3082	0.4762	-0.0511	0.2985	-0.3225	0.4356	-0.0602	0.1066	0.083	-0.0465	0.3124	0.6071	-0.0886	-0.1007	-0.0633	0.0821	-0.0325	-0.0372	0.1407	0.1641	0.3863	0.8434	41.3367	41.6948
117	0.4556	0.0123	0.4512	0.9247	-0.3745	0.6063	0.0209	-0.0476	0.0762	0.0237	0.3443	0.558	0.0124	-0.235	-0.1121	0.0594	0.0188	0.0303	0.1193	0.0863	0.4409	-2.0325	32.4139	49.9426
118	0.2326	0.4297	0.2937	1.0971	0.428	0.45	0.0409	-0.1461	0.0946	0.335	0.0713	0.2415	-0.2391	0.0281	-0.0492	0.1607	0.0501	0.0846	0.0426	0.0319	0.1755	5.8906	36.7069	64.6664
119	0.4414	-0.1691	0.5874	0.1554	-0.0561	0.3315	-0.3016	-0.7184	-0.025	0.4634	0.0538	0.2038	-0.3112	-0.5364	0.1017	0.3744	0.0706	0.0257	0.152	-0.0888	0.3884	10.9385	40.5511	72.4615
120	0.4764	0.5904	-0.0673	-0.1146	0.4059	0.7842	0.0365	0.0201	0.0466	-0.1576	0.0062	-0.0162	0.0987	-0.102	0.0066	0.1848	0.0244	0.0518	0.1016	-0.025	0.1923	20.748	-59.9218	53.0019
121	0.0426	0.2054	-0.1968	-0.0712	-0.0312	0.0338	0.1963	0.0411	0.1707	-0.4676	-0.1527	0.2948	0.1612	-0.0335	-0.0271	0.2943	-0.0447	0.112	0.1024	0.0181	0.2598	23.7122	-48.2971	34.6253
122	0.5741	-0.5609	-0.2996	-0.1048	-0.4052	0.3526	0.1213	-0.0084	-0.1513	-0.0824	-0.0223	-0.2104	0.2674	0.0604	0.0123	0.2228	-0.0066	0.0638	0.0859	-0.0313	0.2473	27.3767	-59.0362	46.7492
123	0.0662	0.1462	0.2291	0.1456	0.1045	0.1216	-0.24	-0.4483	-0.6744	-0.0036	0.0551	-0.5065	0.7697	-0.3923	0.0288	0.4751	0.0868	0.0711	0.1944	0.0382	0.527	23.5897	-74.9082	49.871
124	-0.0048	0.026	-0.0259	0.0654	-0.1128	0.1518	-0.5724	0.5433	0.2164	-0.1426	0.0428	-0.0384	-0.1519	0.0845	0.0144	0.8948	-0.0837	-0.2001	0.4327	0.0316	1.0384	20.6334	-79.9707	40.4914
125	0.0082	-0.2641	-0.1274	0.0774	0.0008	0.0967	-0.0005	-0.0922	0.1262	-0.3055	-0.2677	-0.1956	0.999	-0.6697	0.0691	0.46	-0.0875	0.0634	0.3055	-0.0371	0.4034	10.8573	-75.4774	47.0263
126	0.1137	0.1876	0.013	0.0071	0.1106	0.049	-0.1162	-0.0841	0.2227	-0.2206	-0.0198	-0.0415	-0.2578	-0.3402	0.0344	0.259	0.0169	-0.0146	0.1416	0.0005	0.2932	8.9301	-61.5795	39.547
127	0.0021	-0.0084	-0.0106	0.0538	0.0298	0.0114	0.1045	-0.0044	0.1453	0.2298	0.3222	0.0741	0.178	0.0447	0.0038	0.5262	-0.1359	-0.0258	0.3683	0.0858	0.3582	1.9845	-72.8663	45.4687
128	0.0618	0.2923	-0.2197	0.1069	-0.1618	0.1557	-0.0728	-0.1949	-0.0018	-0.2483	0.0547	0.0137	0.2558	0.3075	-0.0675	0.2884	-0.1497	-0.0949	0.235	0.0314	0.1577	3.5454	-32.7703	21.6024
129	0.6007	-0.1873	-0.2082	0.7665	-0.7303	0.9151	-0.1947	0.0002	0.0759	-0.159	0.3055	0.1643	0.1058	-0.0634	-0.0714	0.2223	-0.0357	-0.0054	0.1493	0.0053	0.1647	4.6417	-36.2279	38.5369
130	0.01	0.0936	0.0877	0.6596	0.3611	0.1535	0.0529	0.022	-0.0507	-0.1538	0.1171	-0.0134	0.0116	-0.0733	-0.0702	0.2748	-0.2457	-0.135	0.2841	0.0991	0.2505	-10.3975	-31.2625	24.5847
131	0.1846	0.1212	-0.2558	0.161	0.4752	0.0566	-0.1332	0.3372	-0.0957	-0.3392	0.1996	0.1678	0.1955	-0.1352	-0.0054	0.434	-0.2381	-0.116	0.2602	-0.0132	0.1776	-0.571	-35.824	17.9167
132	0.0236	-0.0106	-0.1348	0.0909	0.0655	0.1865	0.1609	-0.2154	0.1457	-0.5293	0.2095	0.2779	0.3387	-0.1488	-0.0227	0.7089	-0.4042	-0.0796	0.368	-0.0535	0.3912	-6.6949	-38.7037	10.6936
133	-0.021	0.012	0.0069	0.0878	0.0117	-0.0545	0.7842	-0.0324	-0.0092	-0.8331	-0.37	0.6164	0.0272	-0.0038	-0.0154	0.5635	-0.1774	-0.193	0.5169	0.1466	0.3898	3.3001	44.3054	-24.5915
134	1.0056	-0.0103	-0.2549	1.0126	0.1232	0.3854	0.0815	0.1346	0.0707	-0.8291	0.2523	-0.4027	0.0452	-0.1213	0.1463	0.6964	-0.1912	0.1471	0.3106	-0.0029	0.0846	24.3757	28.6245	-29.5466
135	0.5575	-0.2806	0.0614	0.0882	0.0432	-0.0355	-0.0921	0.0866	-0.1381	-0.0483	0.1754	-0.2748	0.1772	-0.201	-0.0913	0.2924	-0.2091	-0.0622	0.3211	0.0362	0.0744	19.3523	22.4547	-16.8801
136	0.0083	-0.1098	-0.1192	1.5625	0.287	-0.1315	0.0143	-0.2294	-0.1548	-0.0934	0.094	0.627	0.108	-0.3068	-0.0336	0.32	-0.1888	-0.0876	0.4777	0.0861	0.0246	9.0392	29.0264	-18.7189
137	0.7135	-0.0032	0.5604	0.1719	0.1378	-0.1434	0.1222	0.2355	0.0149	-0.876	-0.0001	0.0416	0.0814	0.0058	-0.0409	0.6407	-0.2093	-0.0801	0.4129	0.0947	0.1306	14.5445	23.3519	-28.6321
138	0.0611	0.0141	0.0107	0.0135	-0.0316	-0.1221	0.2573	0.456	0.4318	-0.8293	-0.2596	0.0649	-0.4492	-0.3365	-0.0509	1.3873	0.0239	-0.1182	0.694	0.1645	0.1797	16.1189	30.9621	-40.5852
139	0.0143	0.0347	0.1144	-0.0124	0.0457	0.0031	0.5369	0.1814	-0.0728	-0.9161	0.0492	0.0553	-0.0245	0.0516	-0.0133	1.5509	-0.0499	0.2997	0.9052	-0.0968	0.3832	24.9471	22.9425	-44.8284
140	0.2804	0.7704	-0.1919	1.8917	-0.0032	0.802	-0.0005	0.231	0.1352	-0.7414	-0.0519	-1.7774	0.4271	0.1657	-0.0448	0.7279	-0.1827	0.3439	0.5002	0.018	0.3724	31.9116	23.8639	-33.5386
141	0.1044	-0.268	-0.0951	0.7338	-0.6662	0.2468	-0.0799	0.0941	0.1459	-0.2481	0.0929	0.3352	0.2748	-0.1032	0.0126	0.3472	-0.1486	0.0385	0.1794	-0.0141	0.0849	36.8033	-3.7956	-4.0938
142	0.083	-0.0942	-0.1123	0.1055	0.0134	-0.0533	-0.222	0.2254	-0.1233	-0.1824	0.1415	0.1024	-0.1728	-0.2952	0.0061	0.3865	-0.1785	-0.0125	0.3327	0.0237	0.2195	32.6706	7.2314	-6.0772
143	-0.0322	0.5716	0.2132	0.9124	0.4518	0.1692	-0.1448	0.0486	0.1114	-0.0747	0.0284	0.0345	-0.036	0.0375	0.0581	0.2416	-0.1221	-0.0238	0.2344	0.0405	0.0613	37.5194	14.7795	-3.9486
144	-0.062	-0.0702	-0.0189	-0.3141	0.1095	0.5694	0.1967	0.2859	-1.341	-0.3951	0.0666	0.3184	0.3603	0.1603	0.6933	0.2857	-0.0966	0.2413	0.1747	-0.0401	-0.7609	45.9453	-4.8783	-5.062
145	0.0447	0.0389	-0.0427	0.3225	0.1878	0.0613	0.1952	-0.1387	-0.6938	-0.2395	-0.0765	-0.8547	0.2694	0.1052	0.2418	0.5447	-0.0878	0.2955	0.2758	-0.4017	-2.0242	46.1317	-12.6705	-12.4519
146	-0.0447	0.6456	-0.0916	0.4158	-0.5242	0.4041	0.5053	0.3862	0.6917	-0.1372	-0.1051	0.4572	-0.3603	0.125	0.5891	0.2909	0.3411	-0.1386	0.7743	0.6231	0.226	12.0324	64.3129	-4.8622
147	0.8737	0.0809	-0.2429	-0.1053	0.2495	0.7473	0.2728	0.0271	0.4742	-0.246	-0.005	-0.0329	-0.0633	-0.3069	-0.2165	0.2027	-0.0147	0.0333	0.116	0.129	0.3342	24.6387	64.052	16.5673
148	0.049	-0.2273	-0.0612	-0.0389	-0.1075	0.8908	0.216	-0.0562	0.2551	0.0083	0.1632	-0.5712	-0.0054	-0.6896	-0.0559	0.3145	-0.057	-0.0122	0.1167	0.0168	0.2296	35.8274	46.3842	17.13
149	1.2724	-0.2529	-0.3282	0.4564	0.1284	1.3833	0.2136	-0.029	0.5301	-0.2062	-0.034	-0.0144	-0.163	-0.5051	-0.194	0.2648	0.0269	0.0606	0.1198	0.2276	0.2364	28.015	58.908	7.3569
150	-0.0164	0.0657	-0.0781	0.0458	0.2243	0.0941	0.4103	0.2731	0.3235	-0.7097	0.2909	-0.2179	-0.5544	-0.4722	-0.0646	0.7786	0.0687	0.2884	0.2555	0.3201	0.6161	31.0298	75.0706	5.1635
151	0.0972	-0.0772	-0.0965	0.0591	0.1442	0.1883	0.2816	-0.047	0.5922	-0.1108	0.2017	-0.5223	-0.8896	0.1242	-0.0344	0.5868	-0.0377	0.2567	0.1297	0.1288	0.5897	33.0187	78.0844	16.9771
152	0.1961	0.0133	-0.1673	0.0357	0.0831	0.1762	-0.0665	-0.3014	-0.0545	0.2437	0.1015	-0.6386	0.1775	0.182	-0.0276	0.3187	-0.0774	0.0256	0.0932	0.0649	0.4662	37.9107	62.0163	24.6923
153	0.0173	-0.0259	-0.0398	0.0411	0.0436	0.0252	0.5029	0.1738	0.1375	-0.0207	0.1203	-0.1517	0.2003	-0.1573	-0.0319	0.4109	-0.0658	0.1872	0.3309	0.0868	0.7102	30.903	76.2668	27.6949
154	0.7086	-0.3253	0.4897	0.2666	-0.3078	0.0625	0.133	0.3933	-0.0748	-0.0354	-0.2833	0.0008	-0.0285	-0.0408	-0.0059	0.1372	-0.021	-0.0397	0.1878	0.0424	0.1507	41.6844	36.6364	41.2733
155	1.3548	-0.1065	-0.0436	0.4468	-0.314	-0.069	0.0684	0.0763	-0.1038	0.0046	0.0261	0.2079	-0.039	0.0327	-0.0503	0.1941	-0.0214	-0.0411	0.1448	0.0201	0.1723	26.7296	43.9334	36.5015
156	0.3672	0.1522	-0.0138	0.1368	0.0513	0.2397	-0.0534	-0.052	0.0119	-0.1137	0.018	-0.0807	-0.1152	-0.1242	0.0193	0.1693	-0.0327	-0.0263	0.1741	-0.0263	0.2032	36.9478	40.8921	54.4876
157	0.4223	0.2124	-0.3098	-0.0017	0.4368	0.2442	-0.0417	-0.0753	0.0052	-0.0302	0.0805	-0.1445	-0.0325	0.1793	-0.0063	0.1321	-0.0792	-0.046	0.1916	0.0024	0.2016	46.2539	40.4097	45.0745
158	0.0766	0.0269	0.0957	0.1381	-0.0012	0.1101	-0.1292	-0.1504	0.6107	0.2999	-0.0876	-0.4072	-0.0029	0.2123	0.0005	0.1813	-0.08	-0.0362	0.2239	-0.0882	0.3068	54.6302	41.278	54.4174
159	1.4245	0.7153	-1.0589	0.3027	-0.1314	0.3558	0.0922	-0.0241	-0.8972	0.6581	-0.8094	-1.3437	-0.0459	0.1997	0.0559	0.49	-0.1162	-0.0876	0.1799	0.1462	0.2976	62.3664	-47.4969	68.2825
160	0.0333	0.1118	-0.4593	-0.0423	0.0662	0.7954	-0.2628	-0.0419	-0.4743	-0.1307	-0.1578	-0.363	0.3564	0.0836	0.2352	0.2051	0.0358	0.13	0.0914	0.0838	0.5204	72.5492	-38.2636	46.053
161	0.4137	0.3339	-0.1008	0.221	0.1267	0.3176	-0.1041	-0.0564	-0.1223	-0.2955	0.1585	-0.4115	0.0871	-0.1051	-0.0254	0.1303	-0.0098	0.0011	0.1321	-0.0325	0.2585	61.5091	-29.4801	48.9679
162	-0.0397	-0.1766	0.4382	0.757	0.2714	0.994	-0.0343	0.0096	-0.0806	0.0929	-0.1164	-0.4107	-0.0452	0.1324	0.1044	0.1595	-0.0265	-0.0364	0.2129	0.0673	0.3351	67.8873	-32.059	57.4243
163	-0.0865	0.052	0.0364	0.0823	0.0704	0.0059	-0.0496	-0.4479	-0.6508	-0.1864	-0.3032	-0.8656	0.3262	0.4404	-0.0215	0.2222	0.0534	0.0175	0.5403	0.3665	0.9732	83.7363	-40.3557	55.6795
164	0.5388	0.2903	0.3879	1.3998	0.7868	0.3182	-0.2809	0.2312	-0.7051	-1.1024	-0.0703	-1.0176	0.2713	0.6078	-0.0368	0.2429	0.16	0.3233	0.2257	0.0801	0.8363	81.298	-43.9247	44.9711
165	-0.0052	0.0219	-0.0007	0.0324	0.051	0.0471	-0.0421	0.449	0.1085	-0.653	-0.2746	-0.0148	0.2994	0.3502	0.0325	0.1498	0.0012	-0.0019	0.3142	-0.0128	0.3386	74.2887	-26.5086	38.4765
166	0.321	-0.3358	0.8764	-0.0187	-0.2187	0.6006	0.2999	-0.2707	-0.5632	-0.9488	-0.1367	0.1077	0.4192	-0.5001	0.2247	0.5108	0.0641	0.4016	-0.0422	-0.1715	0.5038	79.5089	-42.0115	36.2248
167	0.166	-0.019	-0.3745	0.1715	-0.402	0.3697	-0.0646	0.0182	-0.0639	0.2909	-0.0028	0.0584	0.1272	0.0758	0.0548	0.1686	-0.0166	0.0382	0.1684	0.0307	0.142	59.2321	-7.5365	22.9155
168	0.128	0.086	0.2087	0.1634	0.1396	0.1001	0.0272	-0.3267	0.1308	-0.1349	0.0173	-0.3263	-0.0939	0.092	0.0406	0.1654	-0.0094	0.0403	0.2152	0.0634	0.2451	57.1339	-16.7472	30.3319
169	0.9266	0.5829	0.5071	0.7269	-0.3018	-0.2929	0.0508	0.027	-0.064	-0.093	0.0115	-0.0648	0.1319	-0.0634	-0.0009	0.1616	0.0245	0.0676	0.1532	-0.0307	0.1344	53.486	-21.8202	23.4015
170	0.3539	0.1411	-0.024	0.1053	-0.0355	-0.0114	-0.1284	0.0898	-0.128	-0.0479	0.0324	-0.0438	0.0026	0.2048	0.0523	0.1407	-0.0456	0.0951	0.2682	0.0084	0.1671	64.0671	-7.1755	15.8811
171	0.2083	0.1197	-0.1508	0.4832	-0.3495	0.0291	-0.0643	0.127	-0.1212	-0.3213	-0.2985	-0.7164	0.2758	0.273	0.0602	0.1957	-0.048	0.1111	0.383	-0.0455	0.2725	70.8251	-7.1858	14.1901
172	-0.1838	0.8048	-0.2656	0.1722	-0.1766	0.4255	-0.2367	-0.0974	-0.3722	-0.022	-0.2627	-0.2022	0.9062	0.6597	0.075	0.3203	0.0779	0.137	0.2189	0.0331	0.4899	51.5201	-60.2597	50.6269
173	0.0737	0.0605	-0.0874	-0.1415	0.0372	0.02	-0.0788	0.3192	-0.4792	-0.0449	-0.0431	-0.2714	0.1984	-0.0111	0.0079	0.3822	-0.0082	0.2113	0.2106	-0.0957	0.502	40.3599	-64.0784	37.6234
174	0.0632	0.5798	-0.0037	0.1953	0.1416	0.5131	-0.1392	0.0055	-0.1504	-0.0768	0.0651	-0.2792	0.0382	-0.0043	0.0081	0.1518	0.0117	0.0793	0.1318	-0.0272	0.3088	47.1513	-46.7217	39.6644
175	0.7693	0.24	0.4349	0.5867	0.2954	0.1839	0.0029	-0.0084	-0.1346	-0.0341	-0.0417	-0.319	0.2553	0.2782	0.0028	0.1638	0.0461	0.1414	0.1258	-0.0081	0.3353	54.2109	-52.5479	40.9161
176	0.0042	0.0795	-0.0228	-0.0565	0.0193	0.0487	-0.4329	-0.4403	-0.7307	-0.0764	0.4123	-0.1174	0.2558	-0.0013	-0.0061	0.372	0.1156	0.1862	0.2686	0.0273	0.8815	57.5096	-66.4006	42.2709
177	0.5735	0.397	-0.4214	0.485	-0.6842	0.2338	-0.4609	0.2662	-0.534	-0.4072	0.1147	0.051	0.5051	-0.0188	0.121	0.4257	0.0756	0.1983	0.1145	-0.1431	0.586	53.4249	-69.4975	32.1714
178	0.4846	-0.0866	0.1289	0.066	-0.0042	1.4204	0.5479	0.2967	-0.0349	-0.3475	0.1094	0.2787	0.5012	-0.4512	0.0454	0.2322	0.0389	0.1827	0.0877	-0.0657	0.3127	48.2858	-52.4803	23.4001
179	-0.0091	0.0357	0.0551	-0.1017	0.0209	-0.0221	-0.7166	0.1771	-0.0819	-0.2503	0.6057	0.0954	0.1052	-0.6742	0.0306	0.3708	-0.1855	0.1533	0.2487	-0.1631	0.4351	43.2816	-67.3176	25.5207
180	-0.4143	0.4463	0.1619	-0.0803	-0.4094	0.3787	0.2776	-0.0654	-0.0579	0.044	-0.2637	-0.0812	0.1149	0.0646	-0.0171	0.4127	-0.0938	0.0707	0.1964	-0.038	0.1844	35.4813	-28.3217	10.4718
181	0.7534	0.292	0.198	0.6507	-0.3406	0.2582	-0.0652	-0.0332	-0.2136	-0.3042	0.081	0.0254	0.0312	0.0741	0.0065	0.2369	-0.0496	0.0606	0.1075	-0.0418	0.1756	29.5487	-37.549	23.8846
182	0.4091	-0.1232	-0.0125	0.3294	-0.0515	0.0028	0.1162	-0.1498	-0.1027	-0.3412	0.0156	0.0382	0.0529	-0.0622	-0.0314	0.476	-0.1559	-0.0083	0.1637	-0.0838	0.1013	23.3739	-33.8857	4.2779
183	0.7429	-0.3313	-0.2242	0.3478	-0.2383	0.0788	0.1072	0.2342	-0.1088	-0.5539	-0.0364	-0.0114	0.1313	0.1577	0.1288	0.3985	-0.1035	0.0959	0.173	-0.1	0.0761	35.3535	-30.3095	3.9564
184	0.6608	-0.1563	-0.392	0.2023	0.4631	1.0574	-0.4832	-0.2648	-0.9373	-0.3499	-0.0736	-0.2209	0.2781	0.4392	-0.7509	0.5035	-0.1243	0.1317	-0.0791	-0.362	0.0109	37.6878	-33.8611	-3.6187

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Selection details	Auth asym-ID	Auth seq-ID
1	X-RAY DIFFRACTION	1	(chain 1 and resid 9:23)	1	9 - 23
2	X-RAY DIFFRACTION	2	(chain 1 and resid 24:45)	1	24 - 45
3	X-RAY DIFFRACTION	3	(chain 1 and resid 46:84)	1	46 - 84
4	X-RAY DIFFRACTION	4	(chain 1 and resid 85:97)	1	85 - 97
5	X-RAY DIFFRACTION	5	(chain 1 and resid 98:150)	1	98 - 150
6	X-RAY DIFFRACTION	6	(chain 1 and resid 151:165)	1	151 - 165
7	X-RAY DIFFRACTION	7	(chain 1 and resid 166:206)	1	166 - 206
8	X-RAY DIFFRACTION	8	(chain 1 and resid 207:234)	1	207 - 234
9	X-RAY DIFFRACTION	9	(chain 2 and resid 301:354)	2	301 - 354
10	X-RAY DIFFRACTION	10	(chain 2 and resid 355:388)	2	355 - 388
11	X-RAY DIFFRACTION	11	(chain 2 and resid 389:462)	2	389 - 462
12	X-RAY DIFFRACTION	12	(chain 2 and resid 463:502)	2	463 - 502
13	X-RAY DIFFRACTION	13	(chain 2 and resid 503:522)	2	503 - 522
14	X-RAY DIFFRACTION	14	(chain A and resid 9:40)	A	9 - 40
15	X-RAY DIFFRACTION	15	(chain A and resid 41:51)	A	41 - 51
16	X-RAY DIFFRACTION	16	(chain A and resid 52:67)	A	52 - 67
17	X-RAY DIFFRACTION	17	(chain A and resid 68:81)	A	68 - 81
18	X-RAY DIFFRACTION	18	(chain A and resid 82:97)	A	82 - 97
19	X-RAY DIFFRACTION	19	(chain A and resid 98:109)	A	98 - 109
20	X-RAY DIFFRACTION	20	(chain A and resid 110:150)	A	110 - 150
21	X-RAY DIFFRACTION	21	(chain A and resid 151:234)	A	151 - 234
22	X-RAY DIFFRACTION	22	(chain B and resid 9:53)	B	9 - 53
23	X-RAY DIFFRACTION	23	(chain B and resid 54:65)	B	54 - 65
24	X-RAY DIFFRACTION	24	(chain B and resid 66:84)	B	66 - 84
25	X-RAY DIFFRACTION	25	(chain B and resid 85:95)	B	85 - 95
26	X-RAY DIFFRACTION	26	(chain B and resid 96:127)	B	96 - 127
27	X-RAY DIFFRACTION	27	(chain B and resid 128:140)	B	128 - 140
28	X-RAY DIFFRACTION	28	(chain B and resid 141:177)	B	141 - 177
29	X-RAY DIFFRACTION	29	(chain B and resid 178:190)	B	178 - 190
30	X-RAY DIFFRACTION	30	(chain B and resid 203:211)	B	203 - 211
31	X-RAY DIFFRACTION	31	(chain B and resid 212:234)	B	212 - 234
32	X-RAY DIFFRACTION	32	(chain C and resid 301:355)	C	301 - 355
33	X-RAY DIFFRACTION	33	(chain C and resid 356:422)	C	356 - 422
34	X-RAY DIFFRACTION	34	(chain C and resid 423:444)	C	423 - 444
35	X-RAY DIFFRACTION	35	(chain C and resid 445:513)	C	445 - 513
36	X-RAY DIFFRACTION	36	(chain C and resid 514:522)	C	514 - 522
37	X-RAY DIFFRACTION	37	(chain D and resid 9:41)	D	9 - 41
38	X-RAY DIFFRACTION	38	(chain D and resid 42:52)	D	42 - 52
39	X-RAY DIFFRACTION	39	(chain D and resid 53:84)	D	53 - 84
40	X-RAY DIFFRACTION	40	(chain D and resid 85:97)	D	85 - 97
41	X-RAY DIFFRACTION	41	(chain D and resid 98:150)	D	98 - 150
42	X-RAY DIFFRACTION	42	(chain D and resid 151:205)	D	151 - 205
43	X-RAY DIFFRACTION	43	(chain D and resid 206:219)	D	206 - 219
44	X-RAY DIFFRACTION	44	(chain D and resid 220:234)	D	220 - 234
45	X-RAY DIFFRACTION	45	(chain E and resid 301:357)	E	301 - 357
46	X-RAY DIFFRACTION	46	(chain E and resid 358:388)	E	358 - 388
47	X-RAY DIFFRACTION	47	(chain E and resid 389:450)	E	389 - 450
48	X-RAY DIFFRACTION	48	(chain E and resid 451:503)	E	451 - 503
49	X-RAY DIFFRACTION	49	(chain E and resid 504:523)	E	504 - 523
50	X-RAY DIFFRACTION	50	(chain F and resid 9:18)	F	9 - 18
51	X-RAY DIFFRACTION	51	(chain F and resid 19:79)	F	19 - 79
52	X-RAY DIFFRACTION	52	(chain F and resid 80:109)	F	80 - 109
53	X-RAY DIFFRACTION	53	(chain F and resid 110:150)	F	110 - 150
54	X-RAY DIFFRACTION	54	(chain F and resid 151:169)	F	151 - 169
55	X-RAY DIFFRACTION	55	(chain F and resid 170:212)	F	170 - 212
56	X-RAY DIFFRACTION	56	(chain F and resid 213:222)	F	213 - 222
57	X-RAY DIFFRACTION	57	(chain F and resid 223:234)	F	223 - 234
58	X-RAY DIFFRACTION	58	(chain G and resid 301:335)	G	301 - 335
59	X-RAY DIFFRACTION	59	(chain G and resid 336:387)	G	336 - 387
60	X-RAY DIFFRACTION	60	(chain G and resid 388:434)	G	388 - 434
61	X-RAY DIFFRACTION	61	(chain G and resid 435:503)	G	435 - 503
62	X-RAY DIFFRACTION	62	(chain G and resid 504:522)	G	504 - 522
63	X-RAY DIFFRACTION	63	(chain H and resid 301:335)	H	301 - 335
64	X-RAY DIFFRACTION	64	(chain H and resid 336:383)	H	336 - 383
65	X-RAY DIFFRACTION	65	(chain H and resid 384:436)	H	384 - 436
66	X-RAY DIFFRACTION	66	(chain H and resid 437:503)	H	437 - 503
67	X-RAY DIFFRACTION	67	(chain H and resid 504:523)	H	504 - 523
68	X-RAY DIFFRACTION	68	(chain I and resid 9:26)	I	9 - 26
69	X-RAY DIFFRACTION	69	(chain I and resid 27:54)	I	27 - 54
70	X-RAY DIFFRACTION	70	(chain I and resid 55:95)	I	55 - 95
71	X-RAY DIFFRACTION	71	(chain I and resid 96:126)	I	96 - 126
72	X-RAY DIFFRACTION	72	(chain I and resid 127:150)	I	127 - 150
73	X-RAY DIFFRACTION	73	(chain I and resid 151:172)	I	151 - 172
74	X-RAY DIFFRACTION	74	(chain I and resid 173:209)	I	173 - 209
75	X-RAY DIFFRACTION	75	(chain I and resid 210:234)	I	210 - 234
76	X-RAY DIFFRACTION	76	(chain J and resid 301:351)	J	301 - 351
77	X-RAY DIFFRACTION	77	(chain J and resid 352:388)	J	352 - 388
78	X-RAY DIFFRACTION	78	(chain J and resid 389:434)	J	389 - 434
79	X-RAY DIFFRACTION	79	(chain J and resid 435:503)	J	435 - 503
80	X-RAY DIFFRACTION	80	(chain J and resid 504:522)	J	504 - 522
81	X-RAY DIFFRACTION	81	(chain K and resid 9:53)	K	9 - 53
82	X-RAY DIFFRACTION	82	(chain K and resid 54:82)	K	54 - 82
83	X-RAY DIFFRACTION	83	(chain K and resid 83:117)	K	83 - 117
84	X-RAY DIFFRACTION	84	(chain K and resid 118:135)	K	118 - 135
85	X-RAY DIFFRACTION	85	(chain K and resid 136:167)	K	136 - 167
86	X-RAY DIFFRACTION	86	(chain K and resid 168:189)	K	168 - 189
87	X-RAY DIFFRACTION	87	(chain K and resid 190:219)	K	190 - 219
88	X-RAY DIFFRACTION	88	(chain K and resid 220:234)	K	220 - 234
89	X-RAY DIFFRACTION	89	(chain L and resid 301:335)	L	301 - 335
90	X-RAY DIFFRACTION	90	(chain L and resid 336:354)	L	336 - 354
91	X-RAY DIFFRACTION	91	(chain L and resid 355:434)	L	355 - 434
92	X-RAY DIFFRACTION	92	(chain L and resid 435:503)	L	435 - 503
93	X-RAY DIFFRACTION	93	(chain L and resid 504:522)	L	504 - 522
94	X-RAY DIFFRACTION	94	(chain M and resid 9:44)	M	9 - 44
95	X-RAY DIFFRACTION	95	(chain M and resid 45:79)	M	45 - 79
96	X-RAY DIFFRACTION	96	(chain M and resid 80:112)	M	80 - 112
97	X-RAY DIFFRACTION	97	(chain M and resid 113:150)	M	113 - 150
98	X-RAY DIFFRACTION	98	(chain M and resid 151:167)	M	151 - 167
99	X-RAY DIFFRACTION	99	(chain M and resid 168:205)	M	168 - 205
100	X-RAY DIFFRACTION	100	(chain M and resid 206:222)	M	206 - 222
101	X-RAY DIFFRACTION	101	(chain M and resid 223:234)	M	223 - 234
102	X-RAY DIFFRACTION	102	(chain N and resid 301:335)	N	301 - 335
103	X-RAY DIFFRACTION	103	(chain N and resid 336:354)	N	336 - 354
104	X-RAY DIFFRACTION	104	(chain N and resid 355:453)	N	355 - 453
105	X-RAY DIFFRACTION	105	(chain N and resid 454:503)	N	454 - 503
106	X-RAY DIFFRACTION	106	(chain N and resid 504:523)	N	504 - 523
107	X-RAY DIFFRACTION	107	(chain O and resid 10:21)	O	10 - 21
108	X-RAY DIFFRACTION	108	(chain O and resid 22:53)	O	22 - 53
109	X-RAY DIFFRACTION	109	(chain O and resid 54:112)	O	54 - 112
110	X-RAY DIFFRACTION	110	(chain O and resid 113:130)	O	113 - 130
111	X-RAY DIFFRACTION	111	(chain O and resid 131:150)	O	131 - 150
112	X-RAY DIFFRACTION	112	(chain O and resid 151:161)	O	151 - 161
113	X-RAY DIFFRACTION	113	(chain O and resid 162:187)	O	162 - 187
114	X-RAY DIFFRACTION	114	(chain O and resid 188:234)	O	188 - 234
115	X-RAY DIFFRACTION	115	(chain P and resid 301:335)	P	301 - 335
116	X-RAY DIFFRACTION	116	(chain P and resid 336:388)	P	336 - 388
117	X-RAY DIFFRACTION	117	(chain P and resid 389:444)	P	389 - 444
118	X-RAY DIFFRACTION	118	(chain P and resid 445:506)	P	445 - 506
119	X-RAY DIFFRACTION	119	(chain P and resid 507:522)	P	507 - 522
120	X-RAY DIFFRACTION	120	(chain Q and resid 9:84)	Q	9 - 84
121	X-RAY DIFFRACTION	121	(chain Q and resid 85:97)	Q	85 - 97
122	X-RAY DIFFRACTION	122	(chain Q and resid 98:150)	Q	98 - 150
123	X-RAY DIFFRACTION	123	(chain Q and resid 151:168)	Q	151 - 168
124	X-RAY DIFFRACTION	124	(chain Q and resid 169:173)	Q	169 - 173
125	X-RAY DIFFRACTION	125	(chain Q and resid 174:208)	Q	174 - 208
126	X-RAY DIFFRACTION	126	(chain Q and resid 209:228)	Q	209 - 228
127	X-RAY DIFFRACTION	127	(chain Q and resid 229:234)	Q	229 - 234
128	X-RAY DIFFRACTION	128	(chain R and resid 301:335)	R	301 - 335
129	X-RAY DIFFRACTION	129	(chain R and resid 336:431)	R	336 - 431
130	X-RAY DIFFRACTION	130	(chain R and resid 432:469)	R	432 - 469
131	X-RAY DIFFRACTION	131	(chain R and resid 470:505)	R	470 - 505
132	X-RAY DIFFRACTION	132	(chain R and resid 506:522)	R	506 - 522
133	X-RAY DIFFRACTION	133	(chain S and resid 9:21)	S	9 - 21
134	X-RAY DIFFRACTION	134	(chain S and resid 22:64)	S	22 - 64
135	X-RAY DIFFRACTION	135	(chain S and resid 65:96)	S	65 - 96
136	X-RAY DIFFRACTION	136	(chain S and resid 97:115)	S	97 - 115
137	X-RAY DIFFRACTION	137	(chain S and resid 116:150)	S	116 - 150
138	X-RAY DIFFRACTION	138	(chain S and resid 151:168)	S	151 - 168
139	X-RAY DIFFRACTION	139	(chain S and resid 169:186)	S	169 - 186
140	X-RAY DIFFRACTION	140	(chain S and resid 187:234)	S	187 - 234
141	X-RAY DIFFRACTION	141	(chain T and resid 301:335)	T	301 - 335
142	X-RAY DIFFRACTION	142	(chain T and resid 336:355)	T	336 - 355
143	X-RAY DIFFRACTION	143	(chain T and resid 356:434)	T	356 - 434
144	X-RAY DIFFRACTION	144	(chain T and resid 435:503)	T	435 - 503
145	X-RAY DIFFRACTION	145	(chain T and resid 504:523)	T	504 - 523
146	X-RAY DIFFRACTION	146	(chain U and resid 9:23)	U	9 - 23
147	X-RAY DIFFRACTION	147	(chain U and resid 24:84)	U	24 - 84
148	X-RAY DIFFRACTION	148	(chain U and resid 85:95)	U	85 - 95
149	X-RAY DIFFRACTION	149	(chain U and resid 96:148)	U	96 - 148
150	X-RAY DIFFRACTION	150	(chain U and resid 149:169)	U	149 - 169
151	X-RAY DIFFRACTION	151	(chain U and resid 170:212)	U	170 - 212
152	X-RAY DIFFRACTION	152	(chain U and resid 213:223)	U	213 - 223
153	X-RAY DIFFRACTION	153	(chain U and resid 224:234)	U	224 - 234
154	X-RAY DIFFRACTION	154	(chain V and resid 301:335)	V	301 - 335
155	X-RAY DIFFRACTION	155	(chain V and resid 336:431)	V	336 - 431
156	X-RAY DIFFRACTION	156	(chain V and resid 432:466)	V	432 - 466
157	X-RAY DIFFRACTION	157	(chain V and resid 467:508)	V	467 - 508
158	X-RAY DIFFRACTION	158	(chain V and resid 509:526)	V	509 - 526
159	X-RAY DIFFRACTION	159	(chain W and resid 9:27)	W	9 - 27
160	X-RAY DIFFRACTION	160	(chain W and resid 28:63)	W	28 - 63
161	X-RAY DIFFRACTION	161	(chain W and resid 64:96)	W	64 - 96
162	X-RAY DIFFRACTION	162	(chain W and resid 97:150)	W	97 - 150
163	X-RAY DIFFRACTION	163	(chain W and resid 151:177)	W	151 - 177
164	X-RAY DIFFRACTION	164	(chain W and resid 178:214)	W	178 - 214
165	X-RAY DIFFRACTION	165	(chain W and resid 215:222)	W	215 - 222
166	X-RAY DIFFRACTION	166	(chain W and resid 223:234)	W	223 - 234
167	X-RAY DIFFRACTION	167	(chain X and resid 301:335)	X	301 - 335
168	X-RAY DIFFRACTION	168	(chain X and resid 336:356)	X	336 - 356
169	X-RAY DIFFRACTION	169	(chain X and resid 357:457)	X	357 - 457
170	X-RAY DIFFRACTION	170	(chain X and resid 458:499)	X	458 - 499
171	X-RAY DIFFRACTION	171	(chain X and resid 500:524)	X	500 - 524
172	X-RAY DIFFRACTION	172	(chain Y and resid 9:40)	Y	9 - 40
173	X-RAY DIFFRACTION	173	(chain Y and resid 41:52)	Y	41 - 52
174	X-RAY DIFFRACTION	174	(chain Y and resid 53:112)	Y	53 - 112
175	X-RAY DIFFRACTION	175	(chain Y and resid 113:150)	Y	113 - 150
176	X-RAY DIFFRACTION	176	(chain Y and resid 151:166)	Y	151 - 166
177	X-RAY DIFFRACTION	177	(chain Y and resid 167:212)	Y	167 - 212
178	X-RAY DIFFRACTION	178	(chain Y and resid 213:222)	Y	213 - 222
179	X-RAY DIFFRACTION	179	(chain Y and resid 223:234)	Y	223 - 234
180	X-RAY DIFFRACTION	180	(chain Z and resid 301:335)	Z	301 - 335
181	X-RAY DIFFRACTION	181	(chain Z and resid 336:431)	Z	336 - 431
182	X-RAY DIFFRACTION	182	(chain Z and resid 432:465)	Z	432 - 465
183	X-RAY DIFFRACTION	183	(chain Z and resid 466:502)	Z	466 - 502
184	X-RAY DIFFRACTION	184	(chain Z and resid 503:524)	Z	503 - 524

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