登録情報 | データベース: PDB / ID: 3erb |
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タイトル | The Crystal Structure of C2b, a Fragment of Complement Component C2 produced during C3-convertase Formation |
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要素 | Complement C2 Complement component 2 |
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キーワード | HYDROLASE (加水分解酵素) / Complement component C2b / C3/C5 convertase / complement control protein (CCP) / short consensus repeat(SCR) / Sushi domain / human complement system (補体) / complement second component C2 / Complement pathway / Disease mutation / Glycoprotein (糖タンパク質) / Immune response (免疫応答) / Innate immunity (自然免疫系) / Polymorphism / Protease (プロテアーゼ) / Secreted (分泌) / Serine protease (セリンプロテアーゼ) / Sushi (寿司) |
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機能・相同性 | 機能・相同性情報
classical-complement-pathway C3/C5 convertase / classical-complement-pathway C3/C5 convertase complex / positive regulation of apoptotic cell clearance / response to thyroid hormone / Activation of C3 and C5 / 補体 / Initial triggering of complement / response to nutrient / complement activation, classical pathway / Regulation of Complement cascade ... classical-complement-pathway C3/C5 convertase / classical-complement-pathway C3/C5 convertase complex / positive regulation of apoptotic cell clearance / response to thyroid hormone / Activation of C3 and C5 / 補体 / Initial triggering of complement / response to nutrient / complement activation, classical pathway / Regulation of Complement cascade / response to bacterium / response to lipopolysaccharide / serine-type endopeptidase activity / 自然免疫系 / タンパク質分解 / extracellular space / extracellular exosome / extracellular region / metal ion binding類似検索 - 分子機能Complement B/C2 / Complement Module, domain 1 / Complement Module; domain 1 / Sushi repeat (SCR repeat) / Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR) / Sushi/SCR/CCP domain / Sushi/CCP/SCR domain profile. / Sushi/SCR/CCP superfamily / von Willebrand factor type A domain / von Willebrand factor (vWF) type A domain ...Complement B/C2 / Complement Module, domain 1 / Complement Module; domain 1 / Sushi repeat (SCR repeat) / Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR) / Sushi/SCR/CCP domain / Sushi/CCP/SCR domain profile. / Sushi/SCR/CCP superfamily / von Willebrand factor type A domain / von Willebrand factor (vWF) type A domain / VWFA domain profile. / von Willebrand factor, type A / von Willebrand factor A-like domain superfamily / リボン / Serine proteases, trypsin family, histidine active site / Serine proteases, trypsin family, serine active site / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin family, histidine active site. / Serine proteases, trypsin domain profile. / Serine proteases, trypsin family, serine active site. / Trypsin-like serine protease / Serine proteases, trypsin domain / トリプシン / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_human.gif) Homo sapiens (ヒト) |
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手法 | X線回折 / 分子置換 / 解像度: 1.8 Å |
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データ登録者 | Narayan, S.V.L. / Krishnan, V. |
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引用 | ジャーナル: Acta Crystallogr.,Sect.D / 年: 2009 タイトル: The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation 著者: Krishnan, V. / Xu, Y. / Macon, K. / Volanakis, J.E. / Narayana, S.V. |
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履歴 | 登録 | 2008年10月1日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2009年3月10日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2023年11月1日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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