Entry Database : PDB / ID : 2vd7 Structure visualization Downloads & linksTitle Crystal Structure of JMJD2A complexed with inhibitor Pyridine-2,4- dicarboxylic acid ComponentsJMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3A Details Keywords OXIDOREDUCTASE / PHOSPHORYLATION / CHROMATIN REGULATOR / IRON / NUCLEUS / ZINC-FINGER / DIOXYGENASE / HOST-VIRUS INTERACTION / TRANSCRIPTION REGULATION / TRANSCRIPTION / METAL-BINDING / HISTONE DEMETHYLATION INHIBITOR JMJC DOMAINFunction / homology Function and homology informationBiological species HOMO SAPIENS (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.25 Å DetailsAuthors Ng, S.S. / von Delft, F. / Pilka, E.S. / Kavanagh, K.L. / McDonough, M.A. / Savitsky, P. / Arrowsmith, C.H. / Weigelt, J. / Edwards, A. / Sundstrom, M. ...Ng, S.S. / von Delft, F. / Pilka, E.S. / Kavanagh, K.L. / McDonough, M.A. / Savitsky, P. / Arrowsmith, C.H. / Weigelt, J. / Edwards, A. / Sundstrom, M. / Schofield, C.J. / Oppermann, U. CitationJournal : J. Med. Chem. / Year : 2008Title : Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.Authors : Rose, N.R. / Ng, S.S. / Mecinovic, J. / Lienard, B.M. / Bello, S.H. / Sun, Z. / McDonough, M.A. / Oppermann, U. / Schofield, C.J. History Deposition Oct 1, 2007 Deposition site : PDBE / Processing site : PDBERevision 1.0 Nov 27, 2007 Provider : repository / Type : Initial releaseRevision 1.1 Jul 13, 2011 Group : Advisory / Version format complianceRevision 1.2 Dec 11, 2013 Group : Database references / Derived calculationsRevision 1.3 Jan 24, 2018 Group : Source and taxonomy / Category : entity_src_genItem : _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id / _entity_src_gen.pdbx_host_org_scientific_name / _entity_src_gen.pdbx_host_org_strainRevision 1.4 Mar 28, 2018 Group : Database references / Source and taxonomy / Category : citation / citation_author / entity_src_genItem : _citation.journal_abbrev / _citation.journal_id_ISSN ... _citation.journal_abbrev / _citation.journal_id_ISSN / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.title / _citation_author.name / _entity_src_gen.pdbx_host_org_vector Revision 1.5 May 8, 2024 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_struct_conn_angle / struct_conn / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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