Entry | Database: PDB / ID: 2an6 |
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Title | Protein-peptide complex |
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Components | - Ubiquitin ligase SIAH1A
- peptide from Phyllopod
![](img/lk-wikipe.gif) |
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Keywords | LIGASE / protein-peptide complex |
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Function / homology | Function and homology information
Antigen processing: Ubiquitination & Proteasome degradation / beta-catenin destruction complex / ubiquitin conjugating enzyme binding / SCF ubiquitin ligase complex / male meiosis I / regulation of multicellular organism growth / canonical Wnt signaling pathway / positive regulation of intrinsic apoptotic signaling pathway / post-embryonic development / protein destabilization ...Antigen processing: Ubiquitination & Proteasome degradation / beta-catenin destruction complex / ubiquitin conjugating enzyme binding / SCF ubiquitin ligase complex / male meiosis I / regulation of multicellular organism growth / canonical Wnt signaling pathway / positive regulation of intrinsic apoptotic signaling pathway / post-embryonic development / protein destabilization / RING-type E3 ubiquitin transferase / protein catabolic process / ubiquitin-protein transferase activity / ubiquitin protein ligase activity / disordered domain specific binding / ubiquitin-dependent protein catabolic process / spermatogenesis / proteasome-mediated ubiquitin-dependent protein catabolic process / neuron apoptotic process / early endosome / cell differentiation / protein ubiquitination / positive regulation of apoptotic process / protein homodimerization activity / zinc ion binding / identical protein binding / nucleus / cytosol / cytoplasmSimilarity search - Function : / Sina, zinc finger / E3 ubiquitin-protein ligase sina/sinah, RING finger / E3 ubiquitin-protein ligase SINA-like, animal / Seven-in-absentia protein, TRAF-like domain / Sina, TRAF-like domain / Zinc finger, SIAH-type / Zinc finger SIAH-type profile. / Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A / Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A ...: / Sina, zinc finger / E3 ubiquitin-protein ligase sina/sinah, RING finger / E3 ubiquitin-protein ligase SINA-like, animal / Seven-in-absentia protein, TRAF-like domain / Sina, TRAF-like domain / Zinc finger, SIAH-type / Zinc finger SIAH-type profile. / Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A / Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A / TRAF-like / Zinc/RING finger domain, C3HC4 (zinc finger) / Herpes Virus-1 / Zinc finger RING-type profile. / Zinc finger, RING-type / Zinc finger, RING/FYVE/PHD-type / Sandwich / 2-Layer Sandwich / Mainly Beta / Alpha BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_mammal.gif) ![](data/taxo/icon/Mus_musculus_S.png) Mus musculus (house mouse) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3 Å |
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Authors | House, C.M. / Hancock, N.C. / Moller, A. / Cromer, B.A. / Fedorov, V. / Bowtell, D.D.L. / Parker, M.W. / Polekhina, G. |
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Citation | Journal: Structure / Year: 2006 Title: Elucidation of the substrate binding site of Siah ubiquitin ligase Authors: House, C.M. / Hancock, N.C. / Moller, A. / Cromer, B.A. / Fedorov, V. / Bowtell, D.D.L. / Parker, M.W. / Polekhina, G. |
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History | Deposition | Aug 11, 2005 | Deposition site: RCSB / Processing site: PDBJ |
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Revision 1.0 | May 30, 2006 | Provider: repository / Type: Initial release |
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Revision 1.1 | Apr 30, 2008 | Group: Version format compliance |
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Revision 1.2 | Jul 13, 2011 | Group: Version format compliance |
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Revision 1.3 | Mar 13, 2024 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_conn_angle / struct_conn / struct_ncs_dom_lim / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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