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- PDB-1rsy: STRUCTURE OF THE FIRST C2-DOMAIN OF SYNAPTOTAGMIN I: A NOVEL CA2+... -
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Open data
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Basic information
Entry | Database: PDB / ID: 1rsy | ||||||
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Title | STRUCTURE OF THE FIRST C2-DOMAIN OF SYNAPTOTAGMIN I: A NOVEL CA2+(SLASH)PHOSPHOLIPID BINDING FOLD | ||||||
![]() | SYNAPTOTAGMIN I![]() | ||||||
![]() | CALCIUM/PHOSPHOLIPID BINDING PROTEIN / CALCIUM-PHOSPHOLIPID BINDING PROTEIN complex | ||||||
Function / homology | ![]() synchronous neurotransmitter secretion / fast, calcium ion-dependent exocytosis of neurotransmitter / positive regulation of calcium ion-dependent exocytosis of neurotransmitter / ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Similarity search - Function | ||||||
Biological species | ![]() ![]() ![]() | ||||||
Method | ![]() | ||||||
![]() | Sutton, R.B. / Sprang, S.R. | ||||||
![]() | ![]() Title: Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold. Authors: Sutton, R.B. / Davletov, B.A. / Berghuis, A.M. / Sudhof, T.C. / Sprang, S.R. #1: ![]() Title: A Single C2 Domain from Synaptotagmin I is Sufficient for High Affinity Ca2+(Slash)Phospholipid Binding Authors: Davletov, B.A. / Sudhof, T.C. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 40.9 KB | Display | ![]() |
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PDB format | ![]() | 27.5 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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1 |
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Unit cell |
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Atom site foot note | 1: CIS PROLINE - PRO 187 |
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Components
#1: Protein | ![]() Mass: 17098.350 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() ![]() ![]() |
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#2: Chemical | ChemComp-SO4 / ![]() |
#3: Water | ChemComp-HOH / ![]() |
Nonpolymer details | HET GROUP TRIVIAL NAME: SULFATE EMPIRICAL FORMULA: SO4 NUMBER OF ATOMS IN GROUP: 5 ADDITIONAL ...HET GROUP TRIVIAL NAME: SULFATE EMPIRICAL FORMULA: SO4 NUMBER OF ATOMS IN GROUP: 5 ADDITIONAL |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.13 Å3/Da / Density % sol: 42.24 % | ||||||||||||||||||||||||
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Crystal | *PLUS Density % sol: 40 % | ||||||||||||||||||||||||
Crystal grow![]() | *PLUS Temperature: 21 ℃ / pH: 7.2 / Method: vapor diffusion, hanging drop | ||||||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Diffraction source | Wavelength: 1.5418 |
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Detector | Type: RIGAKU RAXIS IIC / Detector: IMAGE PLATE |
Radiation | Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength![]() |
Reflection | Num. obs: 11214 / % possible obs: 95 % / Observed criterion σ(I): 2 / Redundancy: 2.8 % |
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Processing
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Refinement | Resolution: 1.9→6 Å / σ(F): 2
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Displacement parameters | Biso mean: 24 Å2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 1.9→6 Å
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Refine LS restraints |
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Refinement | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Solvent computation | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints | *PLUS
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