登録情報 | データベース: PDB / ID: 1r58 |
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タイトル | Crystal Structure of MetAP2 complexed with A357300 |
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要素 | Methionine aminopeptidase 2メチオニルアミノペプチダーゼ |
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キーワード | HYDROLASE (加水分解酵素) |
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機能・相同性 | 機能・相同性情報
N-terminal protein amino acid modification / peptidyl-methionine modification / initiator methionyl aminopeptidase activity / メチオニルアミノペプチダーゼ / metalloexopeptidase activity / metalloaminopeptidase activity / aminopeptidase activity / protein processing / Inactivation, recovery and regulation of the phototransduction cascade / RNA binding ...N-terminal protein amino acid modification / peptidyl-methionine modification / initiator methionyl aminopeptidase activity / メチオニルアミノペプチダーゼ / metalloexopeptidase activity / metalloaminopeptidase activity / aminopeptidase activity / protein processing / Inactivation, recovery and regulation of the phototransduction cascade / RNA binding / metal ion binding / 細胞膜 / 細胞質基質 / 細胞質類似検索 - 分子機能 Peptidase M24A, methionine aminopeptidase, subfamily 2 / Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site / Methionine aminopeptidase subfamily 2 signature. / Peptidase M24, methionine aminopeptidase / クレアチナーゼ / Creatinase/methionine aminopeptidase superfamily / Peptidase M24 / Metallopeptidase family M24 / Creatinase/aminopeptidase-like / Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain ...Peptidase M24A, methionine aminopeptidase, subfamily 2 / Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site / Methionine aminopeptidase subfamily 2 signature. / Peptidase M24, methionine aminopeptidase / クレアチナーゼ / Creatinase/methionine aminopeptidase superfamily / Peptidase M24 / Metallopeptidase family M24 / Creatinase/aminopeptidase-like / Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain / Arc Repressor Mutant, subunit A / Winged helix DNA-binding domain superfamily / Winged helix-like DNA-binding domain superfamily / Alpha-Beta Complex / Orthogonal Bundle / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / 分子置換 / 解像度: 1.9 Å |
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データ登録者 | Sheppard, G.S. / Wang, J. / Kawai, M. / BaMaung, N.Y. / Craig, R.A. / Ericken, S.A. / Lynch, L. / Patel, J. / Yang, F. / Searle, X.B. ...Sheppard, G.S. / Wang, J. / Kawai, M. / BaMaung, N.Y. / Craig, R.A. / Ericken, S.A. / Lynch, L. / Patel, J. / Yang, F. / Searle, X.B. / Lou, P. / Park, C. / Kim, K.H. / Henkin, J. / Lesniewski, R. |
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引用 | ジャーナル: Bioorg.Med.Chem.Lett. / 年: 2004 タイトル: 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2. 著者: Sheppard, G.S. / Wang, J. / Kawai, M. / BaMaung, N.Y. / Craig, R.A. / Erickson, S.A. / Lynch, L. / Patel, J. / Yang, F. / Searle, X.B. / Lou, P. / Park, C. / Kim, K.H. / Henkin, J. / Lesniewski, R. |
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履歴 | 登録 | 2003年10月9日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2004年10月12日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月29日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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