登録情報 | データベース: PDB / ID: 1awj |
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タイトル | INTRAMOLECULAR ITK-PROLINE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE |
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要素 | ITK |
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キーワード | TRANSFERASE (転移酵素) / REGULATORY INTRAMOLECULAR COMPLEX / KINASE (キナーゼ) |
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機能・相同性 | 機能・相同性情報
Generation of second messenger molecules / FCERI mediated Ca+2 mobilization / gamma-delta T cell activation / NK T cell differentiation / : / positive regulation of cytokine production / B cell receptor signaling pathway / non-specific protein-tyrosine kinase / non-membrane spanning protein tyrosine kinase activity / cell-cell junction ...Generation of second messenger molecules / FCERI mediated Ca+2 mobilization / gamma-delta T cell activation / NK T cell differentiation / : / positive regulation of cytokine production / B cell receptor signaling pathway / non-specific protein-tyrosine kinase / non-membrane spanning protein tyrosine kinase activity / cell-cell junction / T cell receptor signaling pathway / 獲得免疫系 / intracellular signal transduction / protein phosphorylation / ATP binding / metal ion binding / 細胞核 / 細胞膜 / 細胞質基質類似検索 - 分子機能 Tyrosine-protein kinase ITK, SH3 domain / Tyrosine-protein kinase ITK/TSK, catalytic domain / Zinc finger, Btk motif / BTK motif / Zinc finger Btk-type profile. / Bruton's tyrosine kinase Cys-rich motif / SH3 Domains / PH domain / PH domain profile. / Pleckstrin homology domain. ...Tyrosine-protein kinase ITK, SH3 domain / Tyrosine-protein kinase ITK/TSK, catalytic domain / Zinc finger, Btk motif / BTK motif / Zinc finger Btk-type profile. / Bruton's tyrosine kinase Cys-rich motif / SH3 Domains / PH domain / PH domain profile. / Pleckstrin homology domain. / Pleckstrin homology domain / SH3ドメイン / SH2ドメイン / Src homology 2 (SH2) domain profile. / Src homology 2 domains / SH2ドメイン / SH3 type barrels. / Src homology 3 domains / SH2 domain superfamily / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3ドメイン / Tyrosine-protein kinase, catalytic domain / Tyrosine kinase, catalytic domain / Tyrosine protein kinases specific active-site signature. / PH-like domain superfamily / Tyrosine-protein kinase, active site / Protein tyrosine and serine/threonine kinase / Serine-threonine/tyrosine-protein kinase, catalytic domain / Roll / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_mammal.gif) ![](data/taxo/icon/Mus_musculus_S.png) Mus musculus (ハツカネズミ) |
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手法 | 溶液NMR / simulated annealing |
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データ登録者 | Andreotti, A.H. / Bunnell, S.C. / Feng, S. / Berg, L.J. / Schreiber, S.L. |
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引用 | ジャーナル: Nature / 年: 1997 タイトル: Regulatory intramolecular association in a tyrosine kinase of the Tec family. 著者: Andreotti, A.H. / Bunnell, S.C. / Feng, S. / Berg, L.J. / Schreiber, S.L. |
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履歴 | 登録 | 1997年10月2日 | 処理サイト: BNL |
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改定 1.0 | 1998年1月14日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年3月24日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2022年2月16日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other カテゴリ: database_2 / pdbx_database_status ...database_2 / pdbx_database_status / pdbx_nmr_software / pdbx_struct_assembly / pdbx_struct_oper_list Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.process_site / _pdbx_nmr_software.name |
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改定 1.4 | 2024年5月22日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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