- EMDB-14245: elongated Cascade complex from type I-A CRISPR-Cas system -
+
Open data
ID or keywords:
Loading...
-
Basic information
Entry
Database: EMDB / ID: EMD-14245
Title
elongated Cascade complex from type I-A CRISPR-Cas system
Map data
partial
Sample
Complex: elongated Cascade complex from Pyrococcus furiosus type I-A CRISPR/Cas system
Protein or peptide: CRISPR-associated helicase Cas3
Protein or peptide: Cas11a
DNA: DNA (5'-D(P*TP*AP*CP*AP*AP*GP*GP*GP*A)-3')
Protein or peptide: Cas7a
Protein or peptide: CRISPR-associated endonuclease Cas3-HD
Protein or peptide: Type I-A CRISPR-associated protein Cas5
RNA: crRNA (57-MER)
DNA: DNA (5'-D(P*TP*CP*CP*C)-3')
Protein or peptide: Cas8Roberval (Air Saguenay) Water Aerodrome
Ligand: NICKEL (II) ION
Keywords
elongated Cascade complex / cascade / type I-A / genome editing / ANTIVIRAL PROTEIN
Function / homology
Function and homology information
exonuclease activity / helicase activity / endonuclease activity / defense response to virus / nucleic acid binding / Hydrolases; Acting on ester bonds / hydrolase activity / ATP binding / metal ion binding Similarity search - Function
CRISPR-associated protein, MJ0385 / CRISPR-associated protein (Cas_Csa4) / CRISPR-associated protein, Cas5a type / CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern / CRISPR-associated protein Cas7/Cst2/DevR / CRISPR-associated negative auto-regulator DevR/Csa2 / Helicase Cas3, CRISPR-associated, core / CRISPR-associated Cas3-type HD domain / CRISPR-associated Cas3-type HD domain superfamily / Cas3, HD domain ...CRISPR-associated protein, MJ0385 / CRISPR-associated protein (Cas_Csa4) / CRISPR-associated protein, Cas5a type / CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern / CRISPR-associated protein Cas7/Cst2/DevR / CRISPR-associated negative auto-regulator DevR/Csa2 / Helicase Cas3, CRISPR-associated, core / CRISPR-associated Cas3-type HD domain / CRISPR-associated Cas3-type HD domain superfamily / Cas3, HD domain / HD Cas3-type domain profile. / CRISPR-associated protein Cas5, N-terminal / DEAD/DEAH box helicase / DEAD/DEAH box helicase domain / Helicase conserved C-terminal domain / helicase superfamily c-terminal domain / Superfamilies 1 and 2 helicase C-terminal domain profile. / Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. / DEAD-like helicases superfamily / Helicase, C-terminal / Helicase superfamily 1/2, ATP-binding domain / P-loop containing nucleoside triphosphate hydrolase Similarity search - Domain/homology
CRISPR-associated helicase Cas3 / Type I-A CRISPR-associated protein Cas5 / Uncharacterized protein / Type I-A CRISPR-associated protein Cas7/Csa2 / CRISPR-associated endonuclease Cas3-HD / Type I-A CRISPR-associated protein Cas8a2/Csa4 Similarity search - Component
Biological species
Pyrococcus furiosus DSM 3638 (archaea) / Escherichia coli (E. coli)
Method
single particle reconstruction / cryo EM / Resolution: 3.3 Å
In the structure databanks used in Yorodumi, some data are registered as the other names, "COVID-19 virus" and "2019-nCoV". Here are the details of the virus and the list of structure data.
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)
EMDB accession codes are about to change! (news from PDBe EMDB page)
The allocation of 4 digits for EMDB accession codes will soon come to an end. Whilst these codes will remain in use, new EMDB accession codes will include an additional digit and will expand incrementally as the available range of codes is exhausted. The current 4-digit format prefixed with “EMD-” (i.e. EMD-XXXX) will advance to a 5-digit format (i.e. EMD-XXXXX), and so on. It is currently estimated that the 4-digit codes will be depleted around Spring 2019, at which point the 5-digit format will come into force.
The EM Navigator/Yorodumi systems omit the EMD- prefix.
Related info.:Q: What is EMD? / ID/Accession-code notation in Yorodumi/EM Navigator
Yorodumi is a browser for structure data from EMDB, PDB, SASBDB, etc.
This page is also the successor to EM Navigator detail page, and also detail information page/front-end page for Omokage search.
The word "yorodu" (or yorozu) is an old Japanese word meaning "ten thousand". "mi" (miru) is to see.
Related info.:EMDB / PDB / SASBDB / Comparison of 3 databanks / Yorodumi Search / Aug 31, 2016. New EM Navigator & Yorodumi / Yorodumi Papers / Jmol/JSmol / Function and homology information / Changes in new EM Navigator and Yorodumi