+Open data
-Basic information
Entry | Database: SASBDB / ID: SASDBA9 |
---|---|
Sample | E. coli CcdB2-CcdA2-CcdB2 toxin/antitoxin heterohexamer complex
|
Function / homology | Function and homology information DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity / toxin sequestering activity / negative regulation of DNA-templated DNA replication / protein-containing complex disassembly / toxin-antitoxin complex / plasmid maintenance / transcription repressor complex / negative regulation of DNA-templated transcription / DNA binding Similarity search - Function |
Biological species | Escherichia coli (strain K12) (bacteria) |
Citation | Date: 2017 Apr 7 Title: Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon Authors: Vandervelde A / Drobnak I / Hadži S / Sterckx Y / Welte T / De Greve H / Charlier D / Efremov R / Loris R |
Contact author |
|
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
---|
-Downloads & links
-Models
Model #908 | Type: atomic / Software: Crysol / Radius of dummy atoms: 1.90 A / Chi-square value: 2.480 Search similar-shape structures of this assembly by Omokage search (details) |
---|
-Sample
Sample | Name: E. coli CcdB2-CcdA2-CcdB2 toxin/antitoxin heterohexamer complex Entity id: 507 / 508 / 509 |
---|---|
Buffer | Name: 10 mM Tris 50 mM NaCl / pH: 7.3 |
Entity #507 | Type: protein / Description: Toxin CcdB / Formula weight: 11.706 / Num. of mol.: 2 / Source: Escherichia coli (strain K12) / References: UniProt: P62554 Sequence: MQFKVYTYKR ESRYRLFVDV QSDIIDTPGR RMVIPLASAR LLSDKVSREL YPVVHIGDES WRMMTTDMAS VPVSVIGEEV ADLSHRENDI KNAINLMFWG I |
Entity #508 | Type: protein / Description: Antitoxin CcdA / Formula weight: 8.372 / Num. of mol.: 2 / Source: Escherichia coli (strain K12) / References: UniProt: P62552 Sequence: MKQRITVTVD SDSYQLLKAY DVNISGLVST TMQNEARRLR AERWKAENQE GMAEVARFIE MNGSFADENR DW |
Entity #509 | Type: protein / Description: Toxin CcdB / Formula weight: 11.706 / Num. of mol.: 2 / Source: Escherichia coli (strain K12) / References: UniProt: P62554 Sequence: MQFKVYTYKR ESRYRLFVDV QSDIIDTPGR RMVIPLASAR LLSDKVSREL YPVVHIGDES WRMMTTDMAS VPVSVIGEEV ADLSHRENDI KNAINLMFWG I |
-Experimental information
Beam | Instrument name: SOLEIL SWING / City: Saint-Aubin / 国: France / Type of source: X-ray synchrotronSynchrotron / Wavelength: 0.103 Å / Dist. spec. to detc.: 1.8 mm | ||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Detector | Name: AVIEX / Type: CCD | ||||||||||||||||||||||||||||||||||||
Scan | Title: CcdB2-CcdA2-CcdB2 heterohexamer / Measurement date: Jul 24, 2013 / Storage temperature: 10 °C / Cell temperature: 15 °C / Exposure time: 0.75 sec. / Number of frames: 13 / Unit: 1/A /
| ||||||||||||||||||||||||||||||||||||
Distance distribution function P(R) | Sofotware P(R): GNOM 5.0 / Number of points: 476 /
| ||||||||||||||||||||||||||||||||||||
Result | Type of curve: merged
|