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Open data
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Basic information
Entry | Database: PDB / ID: 8u7y | ||||||
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Title | Structural Basis of Human NOX5 Activation | ||||||
![]() | NADPH oxidase 5![]() | ||||||
![]() | ![]() ![]() ![]() | ||||||
Function / homology | ![]() regulation of fusion of sperm to egg plasma membrane / superoxide-generating NADPH oxidase activity / ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Cui, C. / Jiang, M. / Sun, J. | ||||||
Funding support | ![]()
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![]() | ![]() Title: Structural Basis of Human NOX5 Activation Authors: Cui, C. / Jiang, M. / Sun, J. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 220.2 KB | Display | ![]() |
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PDB format | ![]() | 167.4 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Related structure data | ![]() 42013MC ![]() 8u85C ![]() 8u86C ![]() 8u87C M: map data used to model this data C: citing same article ( |
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Similar structure data | Similarity search - Function & homology ![]() |
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Links
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Assembly
Deposited unit | ![]()
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1 |
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Components
-Protein , 1 types, 2 molecules AB
#1: Protein | ![]() Mass: 82118.992 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() References: UniProt: Q96PH1, ![]() |
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-Non-polymers , 6 types, 13 molecules ![](data/chem/img/FAD.gif)
![](data/chem/img/D12.gif)
![](data/chem/img/D10.gif)
![](data/chem/img/NAP.gif)
![](data/chem/img/HEB.gif)
![](data/chem/img/ZN.gif)
![](data/chem/img/D12.gif)
![](data/chem/img/D10.gif)
![](data/chem/img/NAP.gif)
![](data/chem/img/HEB.gif)
![](data/chem/img/ZN.gif)
#2: Chemical | ![]() #3: Chemical | ![]() #4: Chemical | ![]() #5: Chemical | ![]() #6: Chemical | ChemComp-HEB / #7: Chemical | ChemComp-ZN / | |
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-Details
Has ligand of interest | Y |
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-Experimental details
-Experiment
Experiment | Method: ![]() |
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EM experiment | Aggregation state: PARTICLE / 3D reconstruction method: ![]() |
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Sample preparation
Component | Name: NADPH oxidase 5![]() |
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Molecular weight | Experimental value: NO |
Source (natural) | Organism: ![]() ![]() |
Source (recombinant) | Organism: ![]() ![]() |
Buffer solution | pH: 8 |
Specimen | Embedding applied: NO / Shadowing applied: NO / Staining applied![]() ![]() |
Vitrification![]() | Cryogen name: ETHANE |
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Electron microscopy imaging
Experimental equipment | ![]() Model: Titan Krios / Image courtesy: FEI Company |
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Microscopy | Model: FEI TITAN KRIOS |
Electron gun | Electron source![]() ![]() |
Electron lens | Mode: BRIGHT FIELD![]() |
Image recording | Electron dose: 60 e/Å2 / Film or detector model: GATAN K3 BIOQUANTUM (6k x 4k) |
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Processing
EM software | Name: PHENIX / Version: 1.20_4459: / Category: model refinement | ||||||||||||||||||||||||
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CTF correction![]() | Type: NONE | ||||||||||||||||||||||||
3D reconstruction![]() | Resolution: 4.06 Å / Resolution method: FSC 0.143 CUT-OFF / Num. of particles: 220000 / Symmetry type: POINT | ||||||||||||||||||||||||
Refine LS restraints |
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