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-Structure paper
Title | Structural basis of human monkeypox viral DNA replication inhibition by brincidofovir and cidofovir |
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Journal, issue, pages | To Be Published |
Publish date | May 1, 2023 (structure data deposition date) |
Authors | Xu YX / Wu YQ / Wu XY / Zhang YY / Yang YX / Li DY / Yang B / Gao K / Zhang ZY / Dong CJ |
External links | Search PubMed |
Methods | EM (single particle) |
Resolution | 2.79 - 2.98 Å |
Structure data | EMDB-36068, PDB-8j8f: EMDB-36069, PDB-8j8g: |
Chemicals | ChemComp-DCP: ChemComp-CA:
ChemComp-TXJ: |
Source |
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Keywords | VIRAL PROTEIN / Monkeypox virus / DNA replication holoenzyme / DNA replication machinery / DNA polymerase / B-family DNA polymerase / uracil-DNA glycosylase / MPXV / orthopoxvirus / poxviridae / DNA processivity factor / DNA / CDVpp / cidofovir diphosphate |