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-Structure paper
Title | Crystal Structure of Glucocerebrosidase Containing the N370S mutation: Implication on Chaperon Therapy |
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Journal, issue, pages | To be Published |
Publish date | Oct 26, 2009 (structure data deposition date) |
Authors | Wei, R.R. / Boucher, S. / Hughes, H. / Guziewica, N. / Vanpatten, S. / Pan, C.Q. / Edmunds, T. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | PDB-3keh: |
Chemicals | ChemComp-NDG: ChemComp-SO4: ChemComp-GOL: ChemComp-NAG: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / Glucocerebrosidase / Acid-beta-Glucosidase / N370S / Glucosyceremidase / TIM Barrel / Alternative initiation / Disease mutation / Disulfide bond / Gaucher disease / Glycoprotein / Glycosidase / Ichthyosis / Lipid metabolism / Lysosome / Membrane / Sphingolipid metabolism |