+Search query
-Structure paper
Title | Allosteric modulation of a human protein kinase with monobodies. |
---|---|
Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 116, Page 13937-13942, Year 2019 |
Publish date | Mar 23, 2016 (structure data deposition date) |
Authors | Zorba, A. / Nguyen, V. / Koide, A. / Hoemberger, M. / Zheng, Y. / Kutter, S. / Kim, C. / Koide, S. / Kern, D. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:31239342 |
Methods | X-ray diffraction |
Resolution | 2.06 - 2.55 Å |
Structure data | PDB-5g15: PDB-6c83: |
Chemicals | ChemComp-ACP: ChemComp-MG: ChemComp-SO4: ChemComp-HOH: |
Source |
|
Keywords | TRANSFERASE / AURORA A / MONOBODY / AMPPCP / KINASE / ACTIVATION / ALLOSTERY / CELL CYCLE / CANCER / transferase/inhibitor / transferase-inhibitor complex |