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-Structure paper
Title | Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site |
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Journal, issue, pages | Science, Vol. 323, Page 1610-1614, Year 2009 |
Publish date | Nov 15, 2007 (structure data deposition date) |
Authors | Bostrom, J. / Yu, S.F. / Kan, D. / Appleton, B.A. / Lee, C.V. / Billeci, K. / Man, W. / Peale, F. / Ross, S. / Wiesmann, C. / Fuh, G. |
External links | Science / PubMed:19299620 |
Methods | X-ray diffraction |
Resolution | 2.6 - 2.9 Å |
Structure data | PDB-3bdy: PDB-3be1: |
Chemicals | ChemComp-GOL: ChemComp-HOH: ChemComp-NAG: ChemComp-MES: |
Source |
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Keywords | HORMONE / Fab Complex / Angiogenesis / Developmental protein / Differentiation / Glycoprotein / Growth factor / Heparin-binding / Mitogen / Secreted / TRANSFERASE / ATP-binding / Kinase / Membrane / Nucleotide-binding / Phosphorylation / Receptor / Transmembrane / Tyrosine-protein kinase |