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Showing 1 - 50 of 56 items for (author: spahn, & c.m.t.)

PDB-8b2l:
Cryo-EM structure of the plant 80S ribosome
Method: single particle / : Smirnova J, Loerke J, Kleinau G, Schmidt A, Buerger J, Meyer EH, Mielke T, Scheerer P, Bock R, Spahn CMT, Zoschke R

PDB-8auv:
Cryo-EM structure of the plant 40S subunit
Method: single particle / : Smirnova J, Loerke J, Kleinau G, Schmidt A, Buerger J, Meyer EH, Mielke T, Scheerer P, Bock R, Spahn CMT, Zoschke R

PDB-8azw:
Cryo-EM structure of the plant 60S subunit
Method: single particle / : Smirnova J, Loerke J, Kleinau G, Schmidt A, Buerger J, Meyer EH, Mielke T, Scheerer P, Bock R, Spahn CMT, Zoschke R

PDB-8bgg:
Cryo-EM structure of SARS-CoV-2 spike (Omicron BA.1 variant) in complex with nanobody W25 (map 5, focus refinement on RBD, W25 and adjacent NTD)
Method: single particle / : Modhiran N, Lauer S, Spahn CMT, Watterson D, Schwefel D

PDB-8bev:
Cryo-EM structure of SARS-CoV-2 spike (HexaPro variant) in complex with nanobody W25 (map 3, focus refinement on RBD, W25 and adjacent NTD)
Method: single particle / : Lauer S, Spahn CMT, Schwefel D

PDB-7zn7:
Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and rat STAT2 CCD
Method: single particle / : Lauer S, Spahn CMT, Schwefel D

PDB-7znn:
Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and full-length rat STAT2
Method: single particle / : Lauer S, Spahn CMT, Schwefel D

PDB-7zjw:
Rabbit 80S ribosome as it decodes the Sec-UGA codon
Method: single particle / : Hilal T, Simonovic M, Spahn CMT

PDB-7zjx:
Rabbit 80S ribosome programmed with SECIS and SBP2
Method: single particle / : Hilal T, Simonovic M, Spahn CMT

PDB-7n1p:
Elongating 70S ribosome complex in a classical pre-translocation (PRE-C) conformation
Method: single particle / : Rundlet EJ, Holm M, Schacherl M, Natchiar SK, Altman RB, Spahn CMT, Myasnikov AG, Blanchard SC

PDB-7n2c:
Elongating 70S ribosome complex in a fusidic acid-stalled intermediate state of translocation bound to EF-G(GDP) (INT2)
Method: single particle / : Rundlet EJ, Holm M, Schacherl M, Natchiar KS, Altman RB, Spahn CMT, Myasnikov AG, Blanchard SC

PDB-7n2u:
Elongating 70S ribosome complex in a hybrid-H1 pre-translocation (PRE-H1) conformation
Method: single particle / : Rundlet EJ, Holm M, Schacherl M, Natchiar KS, Altman RB, Spahn CMT, Myasnikov AG, Blanchard SC

PDB-7n2v:
Elongating 70S ribosome complex in a spectinomycin-stalled intermediate state of translocation bound to EF-G in an active, GTP conformation (INT1)
Method: single particle / : Rundlet EJ, Holm M, Schacherl M, Natchiar KS, Altman RB, Spahn CMT, Myasnikov AG, Blanchard SC

PDB-7n30:
Elongating 70S ribosome complex in a hybrid-H2* pre-translocation (PRE-H2*) conformation
Method: single particle / : Rundlet EJ, Holm M, Schacherl M, Natchiar KS, Altman RB, Spahn CMT, Myasnikov AG, Blanchard SC

PDB-7n31:
Elongating 70S ribosome complex in a post-translocation (POST) conformation
Method: single particle / : Rundlet EJ, Holm M, Schacherl M, Natchiar KS, Altman RB, Spahn CMT, Myasnikov AG, Blanchard SC

PDB-7bl2:
pre-50S-ObgE particle state 1
Method: single particle / : Hilal T, Nikolay R, Schmidt S, Spahn CMT

PDB-7bl3:
pre-50S-ObgE particle state 2
Method: single particle / : Hilal T, Nikolay R, Spahn CMT

PDB-7bl4:
in vitro reconstituted 50S-ObgE-GMPPNP-RsfS particle
Method: single particle / : Hilal T, Nikolay R, Spahn CMT

PDB-7bl5:
pre-50S-ObgE particle
Method: single particle / : Hilal T, Nikolay R, Spahn CMT, Schmidt S

PDB-7bl6:
50S-ObgE-GMPPNP particle
Method: single particle / : Hilal T, Nikolay R, Schmidt S, Spahn CMT

PDB-6gov:
Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX
Method: single particle / : Loll B, Krupp F, Said N, Huang Y, Buerger J, Mielke T, Spahn CMT, Wahl MC

PDB-6gz3:
tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-1 (TI-POST-1)
Method: single particle / : Flis J, Holm M, Rundlet EJ, Loerke J, Hilal T, Dabrowski M, Buerger J, Mielke T, Blanchard SC, Spahn CMT, Budkevich TV

PDB-6gz4:
tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-2 (TI-POST-2)
Method: single particle / : Flis J, Holm M, Rundlet EJ, Loerke J, Hilal T, Dabrowski M, Buerger J, Mielke T, Blanchard SC, Spahn CMT, Budkevich TV

PDB-6gz5:
tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-3 (TI-POST-3)
Method: single particle / : Flis J, Holm M, Rundlet EJ, Loerke J, Hilal T, Dabrowski M, Buerger J, Mielke T, Blanchard SC, Spahn CMT, Budkevich TV

PDB-6gc4:
50S ribosomal subunit assembly intermediate state 3
Method: single particle / : Nikolay R, Hilal T, Qin B, Loerke J, Buerger J, Mielke T, Spahn CMT

PDB-6gc6:
50S ribosomal subunit assembly intermediate state 2
Method: single particle / : Nikolay R, Hilal T, Qin B, Loerke J, Buerger J, Mielke T, Spahn CMT

PDB-6gbz:
50S ribosomal subunit assembly intermediate state 5
Method: single particle / : Nikolay R, Hilal T, Qin B, Loerke J, Buerger J, Mielke T, Spahn CMT

PDB-6gc0:
50S ribosomal subunit assembly intermediate state 4
Method: single particle / : Nikolay R, Hilal T, Qin B, Loerke J, Buerger J, Mielke T, Spahn CMT

PDB-6gc7:
50S ribosomal subunit assembly intermediate state 1
Method: single particle / : Nikolay R, Hilal T, Qin B, Loerke J, Buerger J, Mielke T, Spahn CMT

PDB-6gc8:
50S ribosomal subunit assembly intermediate - 50S rec*
Method: single particle / : Nikolay R, Hilal T, Qin B, Loerke J, Buerger J, Mielke T, Spahn CMT

PDB-5m1j:
Nonstop ribosomal complex bound with Dom34 and Hbs1
Method: single particle / : Hilal T, Yamamoto H, Loerke J, Buerger J, Mielke T, Spahn CMT

PDB-3jcj:
Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association
Method: single particle / : Sprink T, Ramrath DJF, Yamamoto H, Yamamoto K, Loerke J, Ismer J, Hildebrand PW, Scheerer P, Buerger J, Mielke T, Spahn CMT

PDB-3jcn:
Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association: Initiation Complex I
Method: single particle / : Sprink T, Ramrath DJF, Yamamoto H, Yamamoto K, Loerke J, Ismer J, Hildebrand PW, Scheerer P, Buerger J, Mielke T, Spahn CMT

PDB-5flx:
Mammalian 40S HCV-IRES complex
Method: single particle / : Yamamoto H, Collier M, Loerke J, Ismer J, Schmidt A, Hilal T, Sprink T, Yamamoto K, Mielke T, Burger J, Shaikh TR, Dabrowski M, Hildebrand PW, Scheerer P, Spahn CMT

PDB-5aj0:
Cryo electron microscopy of actively translating human polysomes (POST state).
Method: single particle / : Behrmann E, Loerke J, Budkevich TV, Yamamoto K, Schmidt A, Penczek PA, Vos MR, Burger J, Mielke T, Scheerer P, Spahn CMT

PDB-4d5y:
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Method: single particle / : Muhs M, Hilal T, Mielke T, Skabkin MA, Sanbonmatsu KY, Pestova TV, Spahn CMT

PDB-4d61:
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Method: single particle / : Muhs M, Hilal T, Mielke T, Skabkin MA, Sanbonmatsu KY, Pestova TV, Spahn CMT

PDB-4d67:
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Method: single particle / : Muhs M, Hilal T, Mielke T, Skabkin MA, Sanbonmatsu KY, Pestova TV, Spahn CMT

PDB-4d5l:
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Method: single particle / : Muhs M, Hilal T, Mielke T, Skabkin MA, Sanbonmatsu KY, Pestova TV, Spahn CMT

PDB-4d5n:
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Method: single particle / : Muhs M, Hilal T, Mielke T, Skabkin MA, Sanbonmatsu KY, Pestova TV, Spahn CMT

PDB-4ujc:
mammalian 80S HCV-IRES initiation complex with eIF5B POST-like state
Method: single particle / : Yamamoto H, Unbehaun A, Loerke J, Behrmann E, Marianne C, Burger J, Mielke T, Spahn CMT

PDB-4ujd:
mammalian 80S HCV-IRES initiation complex with eIF5B PRE-like state
Method: single particle / : Yamamoto H, Unbehaun A, Loerke J, Behrmann E, Marianne C, Burger J, Mielke T, Spahn CMT

PDB-4cxg:
Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement
Method: single particle / : Budkevich TV, Giesebrecht J, Behrmann E, Loerke J, Ramrath DJF, Mielke T, Ismer J, Hildebrand P, Tung CS, Nierhaus KH, Sanbonmatsu KY, Spahn CMT

PDB-4cxh:
Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement
Method: single particle / : Budkevich TV, Giesebrecht J, Behrmann E, Loerke J, Ramrath DJF, Mielke T, Ismer J, Hildebrand P, Tung CS, Nierhaus KH, Sanbonmatsu KY, Spahn CMT

PDB-4uje:
Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement
Method: single particle / : Budkevich TV, Giesebrecht J, Behrmann E, Loerke J, Ramrath DJF, Mielke T, Ismer J, Hildebrand P, Tung CS, Nierhaus KH, Sanbonmatsu KY, Spahn CMT

PDB-4v7b:
Visualization of two tRNAs trapped in transit during EF-G-mediated translocation
Method: single particle / : Ramrath DJF, Lancaster L, Sprink T, Mielke T, Loerke J, Noller HF, Spahn CMT

PDB-4v6t:
Structure of the bacterial ribosome complexed by tmRNA-SmpB and EF-G during translocation and MLD-loading
Method: single particle / : Ramrath DJF, Yamamoto H, Rother K, Wittek D, Pech M, Mielke T, Loerke J, Scheerer P, Ivanov P, Teraoka Y, Shpanchenko O, Nierhaus KH, Spahn CMT

PDB-4v5m:
tRNA tranlocation on the 70S ribosome: the pre-translocational translocation intermediate TI(PRE)
Method: single particle / : Ratje AH, Loerke J, Mikolajka A, Bruenner M, Hildebrand PW, Starosta AL, Doenhoefer A, Connell SR, Fucini P, Mielke T, Whitford PC, Onuchic JN, Yu Y, Sanbonmatsu KY, Hartmann RK, Penczek PA, Wilson DN, Spahn CMT

PDB-4v5n:
tRNA translocation on the 70S ribosome: the post- translocational translocation intermediate TI(POST)
Method: single particle / : Ratje AH, Loerke J, Mikolajka A, Bruenner M, Hildebrand PW, Starosta AL, Doenhoefer A, Connell SR, Fucini P, Mielke T, Whitford PC, Onuchic JN, Yu Y, Sanbonmatsu KY, Hartmann RK, Penczek PA, Wilson DN, Spahn CMT

PDB-4v68:
T. thermophilus 70S ribosome in complex with mRNA, tRNAs and EF-Tu.GDP.kirromycin ternary complex, fitted to a 6.4 A Cryo-EM map.
Method: single particle / : Schuette JC, Spahn CMT

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