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3NHK
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BU of 3nhk by Molmil
X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2
Descriptor: 6,7,8-trimethoxy-1,4-dimethylquinolin-2(1H)-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ...
Authors:Sturdy, M.
Deposit date:2010-06-14
Release date:2012-01-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2
To be Published
1VEQ
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BU of 1veq by Molmil
Mycobacterium smegmatis Dps Hexagonal form
Descriptor: FE (III) ION, starvation-induced DNA protecting protein
Authors:Roy, S, Gupta, S, Das, S, Sekar, K, Chatterji, D, Vijayan, M.
Deposit date:2004-04-03
Release date:2004-06-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.98 Å)
Cite:X-ray analysis of Mycobacterium smegmatis Dps and a comparative study involving other Dps and Dps-like molecules
J.Mol.Biol., 339, 2004
4A6P
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BU of 4a6p by Molmil
RadA C-terminal ATPase domain from Pyrococcus furiosus
Descriptor: DNA REPAIR AND RECOMBINATION PROTEIN RADA, PHOSPHATE ION
Authors:Marsh, M.E, Ehebauer, M.T, Scott, D, Abell, C, Blundell, T.L, Hyvonen, M.
Deposit date:2011-11-08
Release date:2012-11-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.498 Å)
Cite:ATP Half-Sites in Rada and Rad51 Recombinases Bind Nucleotides
FEBS Open Bio, 6, 2016
8BW8
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BU of 8bw8 by Molmil
Crystal structure of the dCNK-SAM-CRIC-PDZ/dHYP-SAM complex
Descriptor: Connector enhancer of KSR protein CNK, GLYCEROL, Protein aveugle
Authors:Maisonneuve, P, Kurinov, I, Sicheri, F.
Deposit date:2022-12-06
Release date:2024-02-21
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction.
Nat.Struct.Mol.Biol., 31, 2024
8BW9
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BU of 8bw9 by Molmil
Cryo-EM structure of the RAF activating complex KSR-MEK-CNK-HYP
Descriptor: Connector enhancer of KSR protein CNK, Dual specificity mitogen-activated protein kinase kinase dSOR1, KSR, ...
Authors:Maisonneuve, P, Fronzes, R, Sicheri, F.
Deposit date:2022-12-06
Release date:2024-02-21
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction.
Nat.Struct.Mol.Biol., 31, 2024
1VJZ
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BU of 1vjz by Molmil
Crystal structure of Endoglucanase (TM1752) from Thermotoga maritima at 2.05 A resolution
Descriptor: endoglucanase
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2004-04-08
Release date:2004-04-13
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of Endoglucanase (TM1752) from Thermotoga maritima at 2.05 A resolution
To be published
4GZT
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BU of 4gzt by Molmil
N2 neuraminidase D151G mutant of A/Tanzania/205/2010 H3N2 in complex with oseltamivir carboxylate
Descriptor: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2012-09-06
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors.
J.Virol., 86, 2012
1VKN
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BU of 1vkn by Molmil
Crystal structure of N-acetyl-gamma-glutamyl-phosphate reductase (TM1782) from Thermotoga maritima at 1.80 A resolution
Descriptor: N-acetyl-gamma-glutamyl-phosphate reductase
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2004-06-11
Release date:2004-06-22
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of N-acetyl-gamma-glutamyl-phosphate reductase (TM1782) from Thermotoga maritima at 1.80 A resolution
To be published
4HGF
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BU of 4hgf by Molmil
Crystal structure of P450 BM3 5F5K heme domain variant complexed with styrene
Descriptor: Bifunctional P-450/NADPH-P450 reductase, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Shehzad, A, Panneerselvam, S, Bocola, M, Mueller-Dieckmann, J, Wilmanns, M, Schwaneberg, U.
Deposit date:2012-10-08
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation.
Chem.Commun.(Camb.), 49, 2013
1H1N
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BU of 1h1n by Molmil
Atomic resolution structure of the major endoglucanase from Thermoascus aurantiacus
Descriptor: ENDO TYPE CELLULASE ENGI
Authors:Van Petegem, F, Vandenberghe, I, Bhat, M.K, Van Beeumen, J.
Deposit date:2002-07-19
Release date:2002-08-12
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Atomic Resolution Structure of the Major Endoglucanase from Thermoascus Aurantiacus
Biochem.Biophys.Res.Commun., 296, 2002
4HGP
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BU of 4hgp by Molmil
Crystal Structure of 2-keto-3-deoxyoctulosonate 8-phosphate phosphohydrolase from Haemophilus influenzae in complex with transition state mimic
Descriptor: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, MAGNESIUM ION, ...
Authors:Daughtry, K.D, Allen, K.N.
Deposit date:2012-10-08
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis.
Biochemistry, 52, 2013
6EXC
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BU of 6exc by Molmil
Crystal structure of DotM cytoplasmic domain (residues 153-380),R314E/R315E
Descriptor: IcmP (DotM)
Authors:Meir, A, Waksman, G.
Deposit date:2017-11-07
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system.
Nat Commun, 9, 2018
3NKD
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BU of 3nkd by Molmil
Structure of CRISP-associated protein Cas1 from Escherichia coli str. K-12
Descriptor: CRISPR-associated protein Cas1
Authors:Nocek, B, Skarina, T, Beloglazova, N, Savchenko, A, Joachimiak, A, Yakunin, A.
Deposit date:2010-06-18
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair.
Mol.Microbiol., 79, 2011
1ADG
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BU of 1adg by Molmil
CRYSTALLOGRAPHIC STUDIES OF TWO ALCOHOL DEHYDROGENASE-BOUND ANALOGS OF THIAZOLE-4-CARBOXAMIDE ADENINE DINUCLEOTIDE (TAD), THE ACTIVE ANABOLITE OF THE ANTITUMOR AGENT TIAZOFURIN
Descriptor: ALCOHOL DEHYDROGENASE, BETA-METHYLENE-SELENAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, ZINC ION
Authors:Li, H, Hallows, W.A, Punzi, J.S, Marquez, V.E, Carrell, H.L, Pankiewicz, K.W, Watanabe, K.A, Goldstein, B.M.
Deposit date:1993-10-18
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin.
Biochemistry, 33, 1994
3MZS
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BU of 3mzs by Molmil
Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol
Descriptor: (3alpha,8alpha,22R)-cholest-5-ene-3,22-diol, Cholesterol side-chain cleavage enzyme, ISOPROPYL ALCOHOL, ...
Authors:Stout, C.D, Annalora, A, Mast, N, Pikuleva, I.
Deposit date:2010-05-12
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1.
J.Biol.Chem., 286, 2011
1H4P
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BU of 1h4p by Molmil
Crystal structure of exo-1,3-beta glucanse from Saccharomyces cerevisiae
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUCAN 1,3-BETA-GLUCOSIDASE I/II, GLYCEROL, ...
Authors:Ferguson, A.D.
Deposit date:2001-05-11
Release date:2003-10-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Er Protein Folding Sensor Udp-Glucose Glycoprotein:Glucosyltransferase Modifies Substrates Distant to Local Changes in Glycoprotein Conformation.
Nat.Struct.Mol.Biol., 11, 2004
1A4Z
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BU of 1a4z by Molmil
ALDEHYDE DEHYDROGENASE FROM BOVINE MITOCHONDRIA COMPLEX WITH NAD (REDUCED) AND SAMARIUM (III)
Descriptor: ALDEHYDE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SAMARIUM (III) ION
Authors:Steinmetz, C.G, Hurley, T.D.
Deposit date:1998-02-10
Release date:1998-04-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion.
Structure, 5, 1997
3ATO
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BU of 3ato by Molmil
Glycine ethyl ester shielding on the aromatic surfaces of lysozyme: Implication for suppression of protein aggregation
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION, ...
Authors:Ito, L, Shiraki, K, Hasegawa, K, Kumasaka, T.
Deposit date:2011-01-06
Release date:2012-03-07
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Glycine ethyl ester shielding on the aromatic surfaces of lysozyme: Implication for suppression of protein aggregation
To be Published
4H34
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BU of 4h34 by Molmil
Crystal structure of the tyrosine phosphatase SHP-2 with Q506P mutation
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 11
Authors:Qiu, W, Lin, A, Hutchinson, A, Romanov, V, Ruzanov, M, Thompson, C, Lam, K, Kisselman, G, Battaile, K, Chirgadze, N.Y.
Deposit date:2012-09-13
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the tyrosine phosphatase SHP-2 with Q506P mutation
To be Published
1GZ3
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BU of 1gz3 by Molmil
Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, FUMARIC ACID, MANGANESE (II) ION, ...
Authors:Yang, Z, Lanks, C.W, Tong, L.
Deposit date:2002-05-14
Release date:2003-05-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Mechanism for the Regulation of Human Mitochondrial Nad(P)+-Dependent Malic Enzyme by ATP and Fumarate
Structure, 10, 2002
7XGW
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BU of 7xgw by Molmil
Apo structure of LW domain from Trypanosoma brucei
Descriptor: Transcription elongation factor s-II
Authors:Liao, S, Gao, J, Chen, M, Tu, X.
Deposit date:2022-04-06
Release date:2023-05-31
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023
4ACZ
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BU of 4acz by Molmil
Structure of the GH99 endo-alpha-mannosidase from Bacteroides thetaiotaomicron
Descriptor: ENDO-ALPHA-MANNOSIDASE, GLYCEROL
Authors:Thompson, A.J, Williams, R.J, Hakki, Z, Alonzi, D.S, Wennekes, T, Gloster, T.M, Songsrirote, K, Thomas-Oates, J.E, Wrodnigg, T.M, Spreitz, J, Stuetz, A.E, Butters, T.D, Williams, S.J, Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
1VQ9
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BU of 1vq9 by Molmil
The structure of CCA-PHE-CAP-BIO and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*AP*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VM6
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BU of 1vm6 by Molmil
Crystal structure of Dihydrodipicolinate reductase (TM1520) from Thermotoga maritima at 2.27 A resolution
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Dihydrodipicolinate reductase, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2004-09-03
Release date:2004-09-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of Dihydrodipicolinate reductase (TM1520) from Thermotoga maritima at 2.27 A resolution
To be published
1H4H
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BU of 1h4h by Molmil
Oligosaccharide-binding to family 11 xylanases: both covalent intermediate and mutant-product complexes display 2,5B conformations at the active-centre
Descriptor: XYLANASE, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-xylopyranose
Authors:Sabini, E, Wilson, K.S, Danielsen, S, Schulein, M, Davies, G.J.
Deposit date:2001-05-11
Release date:2002-05-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Catalysis and Specificity in Enzymatic Glycoside Hydrolysis: A 2,5B Conformation for the Glycosyl-Enzyme Intermediate Revealed by the Structure of the Bacillus Agaradhaerens Family 11 Xylanase.
Chem.Biol., 6, 1999

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